Topic 54 -- Abstracts with Biological Entities (English) - 75 Topics

cite ad title authors publish year publish time dataset abstract mentions covid pmcid pubmed id doi cord uid topic weight Similarity scispacy Similarity specter
1 Desai_2013 Synthesis, antimicrobial and cytotoxic activities of some novel thiazole clubbed 1,3,4-oxadiazoles Desai, N.C.; Bhatt, Nayan; Somani, Hardik; Trivedi, Amit 2013 2013-09-30 PMC N PMC7127452 23835482.0 10.1016/j.ejmech.2013.06.029 mqcwk2ow 0.966055 Mohammat_2009, Rajić_2010, Zhang_2018, Kuo_R_2009 Sahoo_2016, Zhong_2017, Grazioso_2012, Cihan-Üstündağ_2019
2 Bosc_2010 Synthesis and in vitro cytostatic activity of new β-d-arabino furan[1′,2′:4,5]oxazolo- and arabino-pyrimidinone derivatives Bosc, Jean-Jacques; Latxague, Laurent; Léger, Jean-Michel; Balzarini, Jan; Forfar, Isabelle; Jarry, Christian; Guillon, Jean 2010 2010-02-28 PMC N PMC7115621 19910080.0 10.1016/j.ejmech.2009.10.032 5mtmkpfv 0.962570 Desai_2013, Zhang_2018, Karki_2012, Zhang_2007 Mehellou_2010, Grazioso_2012, Gazivoda_2008, Tsoukala_2010
3 Głowacka_2015 Phosphonylated Acyclic Guanosine Analogues with the 1,2,3-Triazole Linker Głowacka, Iwona E.; Andrei, Graciela; Schols, Dominique; Snoeck, Robert; Piotrowska, Dorota G. 2015 2015-10-16 COMM-USE N PMC6332235 26501246.0 10.3390/molecules201018789 ptrw5uhw 0.955076 Zhang_2007, Oosterhoff_2015, Brake_2008, Yamaguchi_1991, Hansen_2018 Pomeisl_2019, Głowacka_2016, Carbone_2013, Tsoukala_2010
4 Ikejiri_2007 Synthesis and biological evaluation of nucleoside analogues having 6-chloropurine as anti-SARS-CoV agents Ikejiri, Masahiro; Saijo, Masayuki; Morikawa, Shigeru; Fukushi, Shuetsu; Mizutani, Tetsuya; Kurane, Ichiro; Maruyama, Tokumi 2007 2007-05-01 PMC N PMC7126875 17336519.0 10.1016/j.bmcl.2007.02.026 nltbvlzq 0.940386 Naito_2007, Novikov_2011, Shin_2018, Pastuch-Gawołek_2019 Pérez-Faginas_2011, Cho_A_2012, Ramajayam_2010
5 Karki_2012 Synthesis and biological evaluation of 2-(5-substituted-1-((diethylamino)methyl)-2-oxoindolin-3-ylidene)-N-substituted-hydrazinecarbothioamides Karki, Subhas S.; Kulkarni, Amol A.; Kumar, Sujeet; Veliyath, Suresh Kumar; De Clercq, Erik; Balzarini, Jan 2012 2012-08-26 PMC N PMC7079969 10.1007/s00044-012-0184-x d65ttxkl 0.939992 Largo_2016, David_2013, Abou-Hamdan_2018, Choudhury_2011 Tsoukala_2010, Pomeisl_2019, Głowacka_2015, Manta_2009
6 Kokosza_2013 Design, synthesis, antiviral and cytostatic evaluation of novel isoxazolidine nucleotide analogues with a carbamoyl linker Kokosza, Kamil; Balzarini, Jan; Piotrowska, Dorota G. 2013 2013-03-01 PMC N PMC7127400 23380474.0 10.1016/j.bmc.2013.01.007 gxm0q0uw 0.935079 Brake_2008, Zhang_2007, Berkhout_2006, Naito_2007, Stork_2011 Głowacka_2015, Kokosza_2015, Grazioso_2012, Pérez-Faginas_2011
7 Yang_2009 Design and synthesis of novel chloramphenicol amine derivatives as potent aminopeptidase N (APN/CD13) inhibitors Yang, Kanghui; Wang, Qiang; Su, Li; Fang, Hao; Wang, Xuejian; Gong, Jianzhi; Wang, Binghe; Xu, Wenfang 2009 2009-06-01 PMC N 19423354.0 10.1016/j.bmc.2009.04.038 010lano6 0.930434 Huixiong_Chen_1999, Ramajayam_2010, Torres_2012, Desai_2013
8 Gangarapu_2013 Synthesis of thiocarbohydrazide and carbohydrazide derivatives as possible biologically active agents Gangarapu, Kiran; Manda, Sarangapani; Jallapally, Anvesh; Thota, Sreekanth; Karki, Subhas S.; Balzarini, Jan; De Clercq, Erik; Tokuda, Harukuni 2013 2013-08-23 PMC N PMC7080202 10.1007/s00044-013-0684-3 85xcc71l 0.924274 Choudhury_2011, David_2013, Abou-Hamdan_2018, Largo_2016, Mohammat_2009 Grazioso_2012, Sahoo_2016, Chopade_2016, Carbone_2013
9 Piotrowska_2019 Novel Isoxazolidine and γ-Lactam Analogues of Homonucleosides Piotrowska, Dorota G.; Głowacka, Iwona E.; Schols, Dominique; Snoeck, Robert; Andrei, Graciela; Gotkowska, Joanna 2019 2019-11-06 COMM-USE N PMC6891762 31698778.0 10.3390/molecules24224014 46nyje11 0.916603 Zhang_2007, Kubo_2012, Meng_2008, Brake_2008, Mohammat_2009 Kokosza_2015, Piotrowska_2016, Głowacka_2015, Carbone_2013
10 Piotrowska_2016 New Isoxazolidine-Conjugates of Quinazolinones—Synthesis, Antiviral and Cytostatic Activity Piotrowska, Dorota G.; Andrei, Graciela; Schols, Dominique; Snoeck, Robert; Grabkowska-Drużyc, Magdalena 2016 2016-07-22 COMM-USE N PMC6273226 27455228.0 10.3390/molecules21070959 b68y9hxw 0.915576 Choudhury_2011, Abou-Hamdan_2018, Largo_2016, David_2013, Rajić_2010 Kokosza_2015, Piotrowska_2019, Głowacka_2015, Carbone_2013
11 Kumar_2012 N′-[4-[(Substituted imino)methyl]benzylidene]-substituted benzohydrazides: synthesis, antimicrobial, antiviral, and anticancer evaluation, and QSAR studies Kumar, Pradeep; Narasimhan, Balasubramanian; Ramasamy, Kalavathy; Mani, Vasudevan; Mishra, Rakesh Kumar; Majeed, Abu Bakar Abdul; De Clercq, Erik 2012 2012-12-01 PMC N PMC7087754 10.1007/s00706-012-0877-3 wf36hx8o 0.908118 David_2013, Abou-Hamdan_2018, Largo_2016, Choudhury_2011, Naito_2007 Grazioso_2012, Sahoo_2016, Kumar_2014, Pomeisl_2019
12 El-Faham_2015 Synthesis, Characterization, and Anti-Cancer Activity of Some New N′-(2-Oxoindolin-3-ylidene)-2-propylpentane hydrazide-hydrazones Derivatives El-Faham, Ayman; Farooq, Muhammad; Khattab, Sherine N.; Abutaha, Nael; Wadaan, Mohammad A.; Ghabbour, Hazem A.; Fun, Hoong-Kun 2015 2015-08-13 COMM-USE N PMC6332339 26287132.0 10.3390/molecules200814638 0dddrh4e 0.895535 Zhang_2007, Abou-Hamdan_2018, Choudhury_2011, Largo_2016, David_2013 Carbone_2013, Tsoukala_2010, Głowacka_2015, Grazioso_2012
13 Zhang_2008 Synthesis and in vitro cytotoxicity evaluation of 4-aminoquinoline derivatives Zhang, Haiwen; Solomon, V. Raja; Hu, Changkun; Ulibarri, Gerardo; Lee, Hoyun 2008 2008-02-29 PMC N PMC7125724 17555912.0 10.1016/j.biopha.2007.04.007 s1xrwe4h 0.891446 Naito_2007, Zhang_2007, Berkhout_2006, Bie_C_2016 Sahoo_2016, Carbone_2013, Zhang_2018
14 Kiritsis_2011 Branched-chain C-cyano pyranonucleosides: Synthesis of 3′-C-cyano & 3′-C-cyano-3′-deoxy pyrimidine pyranonucleosides as novel cytotoxic agents Kiritsis, Christos; Manta, Stella; Parmenopoulou, Vanessa; Balzarini, Jan; Komiotis, Dimitri 2011 2011-11-30 PMC N PMC7115479 21917363.0 10.1016/j.ejmech.2011.08.033 y9adr86i 0.889727 David_2013, Choudhury_2011, Abou-Hamdan_2018, Largo_2016, Yang_2010 Tsoukala_2010, Manta_2009, Pomeisl_2019
15 Głowacka_2016 Acyclic nucleoside phosphonates containing the amide bond Głowacka, Iwona E.; Piotrowska, Dorota G.; Andrei, Graciela; Schols, Dominique; Snoeck, Robert; Wróblewski, Andrzej E. 2016 2016-10-26 COMM-USE N PMC5101293 27881885.0 10.1007/s00706-016-1848-x co3bvm5e 0.889534 Largo_2016, Abou-Hamdan_2018, Choudhury_2011, David_2013, Jendrach_2014 Głowacka_2019, Pomeisl_2019, Głowacka_2015, Hocková_2011
16 Kim_M_2011 2,6-Bis-arylmethyloxy-5-hydroxychromones with antiviral activity against both hepatitis C virus (HCV) and SARS-associated coronavirus (SCV) Kim, Mi Kyoung; Yu, Mi-Sun; Park, Hye Ri; Kim, Kyung Bo; Lee, Chaewoon; Cho, Suh Young; Kang, Jihoon; Yoon, Hyunjun; Kim, Dong-Eun; Choo, Hyunah; Jeong, Yong-Joo; Chong, Youhoon 2011 2011-11-30 PMC N PMC7115508 21925774.0 10.1016/j.ejmech.2011.09.005 garchpin 0.877464 Yang_2010, Naito_2007, Vaughan_2012, Kang_2009, Volmer_2010 Grazioso_2012, Mehellou_2010, Ikejiri_2007, Tsoukala_2010
17 Tsoukala_2010 Synthesis of 3-fluoro-6-S-(2-S-pyridyl) nucleosides as potential lead cytostatic agents Tsoukala, Evangelia; Tzioumaki, Niki; Manta, Stella; Riga, Alexandra; Balzarini, Jan; Komiotis, Dimitri 2010 2010-12-31 PMC N PMC7112006 20817215.0 10.1016/j.bioorg.2010.08.001 qcp3r6jb 0.874359 Mohammat_2009, Bouton_2017, MacDonald_2012, Yoshizawa_2020 Manta_2009, Pomeisl_2019, Głowacka_2015
18 Głowacka_2019 Acyclic nucleoside phosphonates containing the amide bond: hydroxy derivatives Głowacka, Iwona E.; Piotrowska, Dorota G.; Andrei, Graciela; Schols, Dominique; Snoeck, Robert; Wróblewski, Andrzej E. 2019 2019-03-01 COMM-USE N PMC7087949 10.1007/s00706-019-2351-y jnz0y54z 0.873403 Largo_2016, David_2013, Choudhury_2011, Abou-Hamdan_2018, Abraham_1990 Głowacka_2016, Pomeisl_2019, Głowacka_2015, Pahonțu_2015
19 Mou_J_2009 Design, synthesis and primary activity evaluation of l-arginine derivatives as amino-peptidase N/CD13 inhibitors Mou, Jiajia; Fang, Hao; Jing, Fanbo; Wang, Qiang; Liu, Yingzi; Zhu, Huawei; Shang, Luqing; Wang, Xuejian; Xu, Wenfang 2009 2009-07-01 PMC N 19454370.0 10.1016/j.bmc.2009.04.056 s49954br 0.864190 Ramajayam_2010, Huixiong_Chen_1999, Naito_2007, Torres_2012 Dude_2008, Grazioso_2012, Konno_2016, Ramajayam_2010
20 Pavić_2016 Design, Synthesis and Biological Evaluation of Novel Primaquine-Cinnamic Acid Conjugates of the Amide and Acylsemicarbazide Type Pavić, Kristina; Perković, Ivana; Gilja, Petra; Kozlina, Filip; Ester, Katja; Kralj, Marijeta; Schols, Dominique; Hadjipavlou-Litina, Dimitra; Pontiki, Eleni; Zorc, Branka 2016 2016-11-28 None N PMC6273687 27916811.0 10.3390/molecules21121629 jmj7se6c 0.847648 Largo_2016, Abou-Hamdan_2018, David_2013, Choudhury_2011, Rajić_2010 Sahoo_2016, Grazioso_2012, Parmenopoulou_2016, Tsoukala_2010
21 Kokosza_2015 Design, antiviral and cytostatic properties of isoxazolidine-containing amonafide analogues Kokosza, Kamil; Andrei, Graciela; Schols, Dominique; Snoeck, Robert; Piotrowska, Dorota G. 2015 2015-07-01 PMC N PMC7126999 26001344.0 10.1016/j.bmc.2015.04.079 wr755jo9 0.846101 Tallmadge_2008, Stork_2011, Ryu_W_2017, Naito_2007, Rice_1992 Piotrowska_2019, Piotrowska_2016, Piotrowska_2012, Głowacka_2015
22 Parmenopoulou_2016 Synthesis of novel N-acyl-β-d-glucopyranosylamines and ureas as potential lead cytostatic agents Parmenopoulou, Vanessa; Manta, Stella; Dimopoulou, Athina; Kollatos, Nikolaos; Schols, Dominique; Komiotis, Dimitri 2016 2016-02-29 PMC N PMC7079967 10.1007/s00044-016-1539-5 e0cxrma6 0.842739 Yang_2010, Shen_2005, Keng_2011, Stork_2011, Zhang_2007 Tsoukala_2010, Grazioso_2012, Mehellou_2010, Rauvolfova_2008
23 Stipković_Babić_2015 Novel halogenated 3-deazapurine, 7-deazapurine and alkylated 9-deazapurine derivatives of l-ascorbic or imino-l-ascorbic acid: Synthesis, antitumour and antiviral activity evaluations Stipković Babić, Maja; Makuc, Damjan; Plavec, Janez; Martinović, Tamara; Kraljević Pavelić, Sandra; Pavelić, Krešimir; Snoeck, Robert; Andrei, Graciela; Schols, Dominique; Wittine, Karlo; Mintas, Mladen 2015 2015-09-18 PMC N PMC7125971 26291038.0 10.1016/j.ejmech.2015.08.008 4x71t5by 0.839289 Zhang_2007, Bie_C_2016, Oosterhoff_2015, Yang_2010, Meng_2008 Carbone_2013, Głowacka_2015, Grazioso_2012, Tsoukala_2010
24 Rajić_2010 The novel amidocarbamate derivatives of ketoprofen: synthesis and biological activity Rajić, Zrinka; Hadjipavlou-Litina, Dimitra; Pontiki, Eleni; Balzarini, Jan; Zorc, Branka 2010 2010-02-03 PMC N PMC7079954 10.1007/s00044-010-9309-2 90wgik7n 0.838486 David_2013, Largo_2016, Abou-Hamdan_2018, Choudhury_2011 Sahoo_2016, Piotrowska_2019, Pomeisl_2019, Carbone_2013
25 Ahadi_2011 Three-component synthesis of new unsymmetrical oxindoles via Friedel–Crafts type reaction Ahadi, Somayeh; Moafi, Leila; Feiz, Afsaneh; Bazgir, Ayoob 2011 2011-05-27 PMC N PMC7126103 10.1016/j.tet.2011.02.054 ktotye00 0.837325 MacDonald_2012, Yazarians_2017, Tarui_2010, Tayade_2015 Tayade_2015, Paramonova_2017, Lin_Z_2012, Riahi_2009
26 Karaküçük-İyidoğan_2011 Novel platinum(II) and palladium(II) complexes of thiosemicarbazones derived from 5-substitutedthiophene-2-carboxaldehydes and their antiviral and cytotoxic activities Karaküçük-İyidoğan, Ayşegül; Taşdemir, Demet; Oruç-Emre, Emine Elçin; Balzarini, Jan 2011 2011-11-30 PMC N PMC7126824 21993152.0 10.1016/j.ejmech.2011.09.031 cekegxop 0.832187 Desai_2013, Mohammat_2009, Perrone_2015, Naito_2007 Sahoo_2016, Pahonțu_2015, Thomson_2010, Cihan-Üstündağ_2019
27 Hocková_2011 Acyclic nucleoside phosphonates with a branched 2-(2-phosphonoethoxy)ethyl chain: Efficient synthesis and antiviral activity Hocková, Dana; Holý, Antonín; Andrei, Graciela; Snoeck, Robert; Balzarini, Jan 2011 2011-08-01 PMC N PMC7125515 21745746.0 10.1016/j.bmc.2011.06.045 fooorxbk 0.831869 Tallmadge_2008, Stork_2011, Kang_2009, Cho_A_2012 Kaiser_2012, Pomeisl_2019, Głowacka_2015, Koszytkowska-Stawińska_2009
28 Piotrowska_2012 Design, synthesis, antiviral and cytostatic evaluation of novel isoxazolidine nucleotide analogues with a 1,2,3-triazole linker Piotrowska, Dorota G.; Balzarini, Jan; Głowacka, Iwona E. 2012 2012-01-31 PMC N PMC7125624 22137458.0 10.1016/j.ejmech.2011.11.021 p4mdzng9 0.831720 MacDonald_2012, Mohammat_2009, Bouton_2017, Thomson_2010 Tsoukala_2010, Pomeisl_2019, Manta_2009, Głowacka_2015
29 Cihan-Üstündağ_2016 Synthesis and antiviral properties of novel indole-based thiosemicarbazides and 4-thiazolidinones Cihan-Üstündağ, Gökçe; Gürsoy, Elif; Naesens, Lieve; Ulusoy-Güzeldemirci, Nuray; Çapan, Gültaze 2016 2016-01-15 PMC N PMC7127696 26707844.0 10.1016/j.bmc.2015.12.008 lbiguzyf 0.830547 Tallmadge_2008, Stork_2011, Meyerson_2017, Rice_1992, Kang_2009 Kokosza_2015, Cihan-Üstündağ_2019, Hamada_2013, Piotrowska_2019
30 Mohammat_2009 Synthesis of 2,3-Dioxo-5-(substituted)arylpyrroles and Their 2-Oxo-5-aryl-3-hydrazone Pyrrolidine Derivatives Mohammat, M.F.; Shaameri, Z.; Hamzah, A.S. 2009 2009-01-07 COMM-USE N PMC6253891 19136912.0 10.3390/molecules14010250 b9wq9gj6 0.830046 MacDonald_2012, Nadaraia_2018, Desai_2013, Desai_2013 Paramonova_2017, Tayade_2015, Riahi_2009, Pomeisl_2019
31 Ryu_Y_2010 SARS-CoV 3CLpro inhibitory effects of quinone-methide triterpenes from Tripterygium regelii Ryu, Young Bae; Park, Su-Jin; Kim, Young Min; Lee, Ju-Yeon; Seo, Woo Duck; Chang, Jong Sun; Park, Ki Hun; Rho, Mun-Chual; Lee, Woo Song 2010 2010-03-15 PMC N PMC7127101 20167482.0 10.1016/j.bmcl.2010.01.152 yhruzu7f 0.829590 Abou-Hamdan_2018, Largo_2016, Choudhury_2011, David_2013, Rajić_2010 Grazioso_2012, Głowacka_2015, Głowacka_2016, Carbone_2013
32 Ouahrouch_2015 Design, Synthesis, and Antiviral Activity of Novel Ribonucleosides of 1,2,3‐Triazolylbenzyl‐aminophosphonates Ouahrouch, Abdelaaziz; Taourirte, Moha; Schols, Dominique; Snoeck, Robert; Andrei, Graciela; Engels, Joachim W.; Lazrek, Hassan B. 2015 2015-11-17 NONCOMM N PMC4832832 26575425.0 10.1002/ardp.201500292 25dwlzpy 0.824573 Choudhury_2011, Largo_2016, Abou-Hamdan_2018, David_2013 Grazioso_2012, Głowacka_2015, Cho_A_2012, Kumarasamy_2017
33 Bouton_2017 Efficient diastereoselective synthesis of a new class of azanucleosides: 2′-homoazanucleosides Bouton, Jakob; Van Hecke, Kristof; Van Calenbergh, Serge 2017 2017-07-27 PMC N PMC7111761 10.1016/j.tet.2017.05.083 2a5q6d45 0.824573 MacDonald_2012, Yang_2008, Yazarians_2017, Yoshizawa_2020 Pomeisl_2019, Cho_A_2012, Kaiser_2012, Grazioso_2012
34 Tichý_2012 Synthesis and antiviral activities of hexadecyloxypropyl prodrugs of acyclic nucleoside phosphonates containing guanine or hypoxanthine and a (S)-HPMP or PEE acyclic moiety Tichý, Tomáš; Andrei, Graciela; Snoeck, Robert; Balzarini, Jan; Dračínský, Martin; Krečmerová, Marcela 2012 2012-09-30 PMC N PMC7115494 22858222.0 10.1016/j.ejmech.2012.07.027 vvw41yvn 0.823724 Tallmadge_2008, Stork_2011, Rice_1992, Meyerson_2017 Krečmerová_2017, Mehellou_2010, Baszczyňski_2018, Pomeisl_2019
35 Gawin_2008 Synthesis and antiviral evaluation of acyclic azanucleosides developed from sulfanilamide as a lead structure Gawin, Rafał; De Clercq, Erik; Naesens, Lieve; Koszytkowska-Stawińska, Mariola 2008 2008-09-15 PMC N PMC7127773 18778942.0 10.1016/j.bmc.2008.08.041 51hlcxaa 0.822328 Yang_2008, Bouton_2017, MacDonald_2012, Thomson_2010 Pomeisl_2019, Koszytkowska-Stawińska_2009, Cho_A_2012, Pérez-Faginas_2011
36 Gazivoda_2008 Synthesis, cytostatic and anti-HIV evaluations of the new unsaturated acyclic C-5 pyrimidine nucleoside analogues Gazivoda, Tatjana; Raić-Malić, Silvana; Krištafor, Vedran; Makuc, Damjan; Plavec, Janez; Bratulić, Siniša; Kraljević-Pavelić, Sandra; Pavelić, Krešimir; Naesens, Lieve; Andrei, Graciela; Snoeck, Robert; Balzarini, Jan; Mintas, Mladen 2008 2008-05-15 None N PMC7127491 18424155.0 10.1016/j.bmc.2008.03.074 bw2go1on 0.818984 Desai_2013, Singh_2013, Zhang_2007, Yang_2010 Hamada_2013, Grazioso_2012, Piotrowska_2019, Carbone_2013
37 Singh_2010 Synthesis, antibacterial and antiviral properties of curcumin bioconjugates bearing dipeptide, fatty acids and folic acid Singh, Ramendra K.; Rai, Diwakar; Yadav, Dipti; Bhargava, A.; Balzarini, J.; De Clercq, E. 2010 2010-03-31 PMC N PMC7115498 20034711.0 10.1016/j.ejmech.2009.12.002 9mbi75de 0.818984 Ban_J_2018, Ishag_2012, Yang_2010, Li_C_2013 Li_X_2019, Sahoo_2016, Cheng_2014, Carbone_2013
38 Cho_A_2012 Synthesis and antiviral activity of a series of 1′-substituted 4-aza-7,9-dideazaadenosine C-nucleosides Cho, Aesop; Saunders, Oliver L.; Butler, Thomas; Zhang, Lijun; Xu, Jie; Vela, Jennifer E.; Feng, Joy Y.; Ray, Adrian S.; Kim, Choung U. 2012 2012-04-15 PMC N PMC7126871 22446091.0 10.1016/j.bmcl.2012.02.105 8q2ecffd 0.817644 Stork_2011, Kang_2009, Meyerson_2017, Rice_1992 Grazioso_2012, Kumarapperuma_2007, Chen_2018, Koszytkowska-Stawińska_2009
39 Głowacka_2013 The synthesis, antiviral, cytostatic and cytotoxic evaluation of a new series of acyclonucleotide analogues with a 1,2,3-triazole linker Głowacka, Iwona E.; Balzarini, Jan; Wróblewski, Andrzej E. 2013 2013-12-31 None N PMC7115586 24219992.0 10.1016/j.ejmech.2013.10.057 y7ld9h2h 0.812576 Tallmadge_2008, Clapham_1991, Oosterhoff_2015, Schat_1987, Compton_2014 Piotrowska_2012, Głowacka_2015, Hamada_2013, Piotrowska_2019
40 Głowacka_2016 Synthesis and the Biological Activity of Phosphonylated 1,2,3-Triazolenaphthalimide Conjugates Głowacka, Iwona E.; Gulej, Rafał; Grzonkowski, Piotr; Andrei, Graciela; Schols, Dominique; Snoeck, Robert; Piotrowska, Dorota G. 2016 2016-10-26 COMM-USE N PMC6273621 27792200.0 10.3390/molecules21111420 2xosvz6c 0.811890 David_2013, Abou-Hamdan_2018, Choudhury_2011, Largo_2016, Schomburg_2013 Głowacka_2015, Carbone_2013, Pomeisl_2019, Piotrowska_2019
41 Novikov_2013 N1,N3-disubstituted uracils as nonnucleoside inhibitors of HIV-1 reverse transcriptase Novikov, Mikhail S.; Valuev-Elliston, Vladimir T.; Babkov, Denis A.; Paramonova, Maria P.; Ivanov, Alexander V.; Gavryushov, Sergey A; Khandazhinskaya, Anastasia L.; Kochetkov, Sergey N.; Pannecouque, Christophe; Andrei, Graciela; Snoeck, Robert; Balzarini, Jan; Seley-Radtke, Katherine L. 2013 2013-03-01 PMC N PMC7125863 23357038.0 10.1016/j.bmc.2012.12.027 9bay2qaq 0.809999 Naito_2007, Perrone_2015, Novikov_2011, Yang_2010 Cho_A_2012, Grazioso_2012, Pérez-Faginas_2011, Im_I_2009
42 Balzarini_2009 Synthesis and anti-HIV studies of 2- and 3-adamantyl-substituted thiazolidin-4-ones Balzarini, Jan; Orzeszko-Krzesińska, Barbara; Maurin, Jan K.; Orzeszko, Andrzej 2009 2009-01-31 PMC N PMC7127420 18420310.0 10.1016/j.ejmech.2008.02.039 sw2ufavv 0.808588 Perrone_2015, Desai_2013, Yang_2010, Singh_2013 Głowacka_2015, Pomeisl_2019, Carbone_2013, Tsoukala_2010
43 Duque_2009 Synthesis and pharmacological evaluation of (2-oxaadamant-1-yl)amines Duque, María D.; Camps, Pelayo; Profire, Lenuta; Montaner, Silvia; Vázquez, Santiago; Sureda, Francesc X.; Mallol, Jordi; López-Querol, Marta; Naesens, Lieve; Clercq, Erik De; Radhika Prathalingam, S.; Kelly, John M. 2009 2009-04-15 None N PMC3217223 19251424.0 10.1016/j.bmc.2009.02.007 x7s1f9gd 0.802779 Torres_2012, Naito_2007, Schoggins_2011, O’Brien_2007 Paramonova_2017, Ramajayam_2010, Cho_A_2012
44 Kaiser_2012 A novel type of acyclic nucleoside phosphonates derived from 2-(phosphonomethoxy)propanoic acid Kaiser, Martin Maxmilian; Jansa, Petr; Dračínský, Martin; Janeba, Zlatko 2012 2012-05-27 PMC N PMC7111817 10.1016/j.tet.2012.03.066 jcgbotnq 0.801542 Naito_2007, Bouton_2017, Perrone_2015, Stork_2011 Hocková_2011, Pomeisl_2019, Głowacka_2015, Kasthuri_2011
45 Hulpia_2016 Exploring the purine core of 3′-C-ethynyladenosine (EAdo) in search of novel nucleoside therapeutics Hulpia, Fabian; Balzarini, Jan; Schols, Dominique; Andrei, Graciela; Snoeck, Robert; Van Calenbergh, Serge 2016 2016-04-15 PMC N PMC7126545 26965865.0 10.1016/j.bmcl.2016.03.005 oshmehqb 0.801156 Tallmadge_2008, Largo_2016, Abou-Hamdan_2018, Choudhury_2011, David_2013 Cho_A_2012, Grazioso_2012, Kaiser_2012, Hamada_2013
46 Kumarasamy_2017 Synthesis and in vitro antiviral evaluation of 4-substituted 3,4-dihydropyrimidinones Kumarasamy, Dhanabal; Roy, Biswajit Gopal; Rocha-Pereira, Joana; Neyts, Johan; Nanjappan, Satheeshkumar; Maity, Subhasis; Mookerjee, Musfiqua; Naesens, Lieve 2017 2017-01-15 PMC N PMC7127791 27979594.0 10.1016/j.bmcl.2016.12.010 cxpgwwjd 0.795756 Yang_2010, Kang_2009, Ryu_W_2017, Shen_2005 Grazioso_2012, Cho_A_2012, Hamada_2013, Głowacka_2015
47 Mehellou_2010 Phosphoramidates of 2′-β-d-arabinouridine (AraU) as phosphate prodrugs; design, synthesis, in vitro activity and metabolism Mehellou, Youcef; Valente, Rocco; Mottram, Huw; Walsby, Elisabeth; Mills, Kenneth I.; Balzarini, Jan; McGuigan, Christopher 2010 2010-04-01 PMC N PMC7125968 20299228.0 10.1016/j.bmc.2010.02.059 ulppgdtv 0.795461 Kang_2009, Stork_2011, Berkhout_2006, Yang_2010, Volmer_2010 Grazioso_2012, McGuigan_2013, Piotrowska_2019, Krečmerová_2017
48 Siddiqui_2011 Synthesis and anticonvulsant properties of 1-(amino-N-arylmethanethio)-3-(1-substituted benzyl-2, 3-dioxoindolin-5-yl) urea derivatives Siddiqui, Nadeem; Alam, M. Shamsher; Stables, James P. 2011 2011-06-30 PMC N PMC7115639 21435751.0 10.1016/j.ejmech.2011.03.004 31e2db0z 0.790971 Desai_2013, Duque_2009, Yadav_2005, Rajić_2010 Pomeisl_2019, Tsoukala_2010, Piotrowska_2012, Karki_2012
49 Yadav_2019 Synthetic, Structural, and Anticancer Activity Evaluation Studies on Novel Pyrazolylnucleosides Yadav, Yogesh; Sharma, Deepti; Kaushik, Kumar; Kumar, Vineet; Jha, Amitabh; Prasad, Ashok K.; Len, Christophe; Malhotra, Sanjay V.; Wengel, Jesper; Parmar, Virinder S. 2019 2019-10-30 COMM-USE N PMC6864788 31671703.0 10.3390/molecules24213922 15rg623y 0.790678 Largo_2016, David_2013, Choudhury_2011, Abou-Hamdan_2018 Desai_2013, Li_Y_2016, Kumarasamy_2017, Carbone_2013
50 Koszytkowska-Stawińska_2009 Synthesis and antiviral activity evaluation of acyclic 2′-azanucleosides bearing a phosphonomethoxy function in the side chain Koszytkowska-Stawińska, Mariola; Clercq, Erik De; Balzarini, Jan 2009 2009-06-01 PMC N PMC7126109 19442526.0 10.1016/j.bmc.2009.04.054 wyvm3rzb 0.788159 Stork_2011, Lin_X_2015, Masante_2015, Otsuka_1999 Cho_A_2012, Pomeisl_2019, Hocková_2011, Kaiser_2012
51 Grabkowska-Drużyc_2018 Isoxazolidine Conjugates of N3-Substituted 6-Bromoquinazolinones—Synthesis, Anti-Varizella-Zoster Virus, and Anti-Cytomegalovirus Activity Grabkowska-Drużyc, Magdalena; Andrei, Graciela; Schols, Dominique; Snoeck, Robert; Piotrowska, Dorota G. 2018 2018-07-28 COMM-USE N PMC6222691 30060562.0 10.3390/molecules23081889 3kjnwpdq 0.787579 Largo_2016, Abou-Hamdan_2018, David_2013, Choudhury_2011, Yang_2010 Kokosza_2015, Piotrowska_2017, Piotrowska_2016, Piotrowska_2019
52 Manta_2009 Dideoxy fluoro-ketopyranosyl nucleosides as potent antiviral agents: Synthesis and biological evaluation of 2,3- and 3,4-dideoxy-3-fluoro-4- and -2-keto-β-d-glucopyranosyl derivatives of N 4-benzoyl cytosine Manta, Stella; Tsoukala, Evangelia; Tzioumaki, Niki; Goropevšek, Aleš; Pamulapati, Ravi Teja; Cencič, Avrelija; Balzarini, Jan; Komiotis, Dimitri 2009 2009-06-30 PMC N PMC7126854 19246130.0 10.1016/j.ejmech.2009.01.020 8hwexeia 0.784372 Yoshizawa_2020, MacDonald_2012, Bouton_2017, Mohammat_2009, Yang_2008 Tsoukala_2010, Pomeisl_2019, Piotrowska_2012
53 Rygielska-Tokarska_2016 Synthesis, antiviral, cytotoxic and cytostatic evaluation of N(1)-(phosphonoalkyl)uracil derivatives Rygielska-Tokarska, Dorota; Andrei, Graciela; Schols, Dominique; Snoeck, Robert; Głowacka, Iwona E. 2016 2016-03-01 PMC N PMC7087680 10.1007/s00706-016-1701-2 utma5d53 0.783349 Choudhury_2011, Largo_2016, David_2013, Abou-Hamdan_2018, Yang_2010 Głowacka_2016, Piotrowska_2019, Głowacka_2015, Mehellou_2010
54 Rao_J_2007 Enantioselective synthesis and antiviral activity of purine and pyrimidine cyclopentenyl C-nucleosides Rao, Jagadeeshwar R.; Schinazi, Raymond F.; Chu, Chung K. 2007 2007-01-15 PMC N PMC7127144 17085053.0 10.1016/j.bmc.2006.10.043 x9uem253 0.782148 Ryu_W_2017, Tallmadge_2008, Lvov_2015, Ayers_2006 Cho_A_2012, Głowacka_2015, Pérez-Faginas_2011, Pomeisl_2019
55 MacDonald_2012 Catalytic Stereoselective Synthesis of Diverse Oxindoles and Spirooxindoles from Isatins MacDonald, Jacob P.; Badillo, Joseph J.; Arevalo, Gary E.; Silva-Garcia, Abel; K. Franz, Annaliese 2012 2012-04-02 PMC N PMC4795923 22449252.0 10.1021/co300003c e4blejns 0.781360 Kale_2010, Yazarians_2017, Tayade_2015, Mlostoń_2010 Tayade_2015, Lin_Z_2012, Paramonova_2017, Ahadi_2011
56 Kumar_2014 Synthesis, antimicrobial, anticancer, antiviral evaluation and QSAR studies of 4-(1-aryl-2-oxo-1,2-dihydro-indol-3-ylideneamino)-N-substituted benzene sulfonamides Kumar, Mahesh; Ramasamy, Kalavathy; Mani, Vasudevan; Mishra, Rakesh Kumar; Majeed, Abu Bakar Abdul; Clercq, Erik De; Narasimhan, Balasubramanian 2014 2014-09-30 PMC N 10.1016/j.arabjc.2012.12.005 jys8vod1 0.773494 Naito_2007, Perrone_2015, Desai_2013, Roman_2015 Sahoo_2016, Grazioso_2012, Bari_2020, Carbone_2013
57 Pomeisl_2019 Synthesis of fluorinated acyclic nucleoside phosphonates with 5-azacytosine base moiety Pomeisl, Karel; Krečmerová, Marcela; Pohl, Radek; Snoeck, Robert; Andrei, Graciela 2019 2019-09-27 PMC N PMC7111758 10.1016/j.tet.2019.130529 0avnx9ac 0.770888 MacDonald_2012, Bouton_2017, Mohammat_2009, Nadaraia_2018 Tsoukala_2010, Głowacka_2015, Manta_2009, Piotrowska_2012
58 Li_Y_2016 Synthesis and Anticancer Activities of Glycyrrhetinic Acid Derivatives Li, Yang; Feng, Ling; Song, Zhi-Fang; Li, Hai-Bei; Huai, Qi-Yong 2016 2016-02-06 COMM-USE N PMC6274419 26861280.0 10.3390/molecules21020199 caimfrq8 0.769056 Zhang_2007, Bie_C_2016, Naito_2007, Brake_2008 Lee_C_2020, Zhang_2018, Sahoo_2016, Wang_2018
59 Park_2011 Synthesis of enantiomerically pure d- and l-bicyclo[3.1.0]hexenyl carbanucleosides and their antiviral evaluation Park, Ah-Young; Kim, Won Hee; Kang, Jin-Ah; Lee, Hye Jin; Lee, Chong-Kyo; Moon, Hyung Ryong 2011 2011-07-01 PMC N PMC7126181 21658957.0 10.1016/j.bmc.2011.05.026 en46kezr 0.765550 Naito_2007, Berkhout_2006, Liu_Y_2008, Stork_2011, Bennasser_2012 Tsoukala_2010, Pomeisl_2019, Głowacka_2015
60 Nadaraia_2018 Synthesis and Biological Activity of Several Modified 5α-Androstanolone Derivatives Nadaraia, N. Sh.; Barbakadze, N. N.; Kakhabrishvili, M. L.; Sylla, B.; Pichette, A.; Makhmudov, U. S. 2018 2018-04-14 PMC N PMC7087839 10.1007/s10600-018-2330-2 ns32sje1 0.765089 Kuo_R_2009, Mohammat_2009, Schmidt_1982, Regnier_2009 Duque_2009, Yadav_2005, Cho_A_2012
61 de_Oliveira_2013 Antimalarial Activity of 4-Metoxychalcones: Docking Studies as Falcipain/Plasmepsin Inhibitors, ADMET and Lipophilic Efficiency Analysis to Identify a Putative Oral Lead Candidate de Oliveira, Michael Eder; Cenzi, Gisele; Nunes, Renata Rachide; Andrighetti, Carla Regina; de Sousa Valadão, Denia Mendes; dos Reis, Cláudia; Simões, Cláudia Maria Oliveira; Nunes, Ricardo José; Júnior, Moacyr Comar; Taranto, Alex Gutterres; Sanchez, Bruno Antonio Marinho; Viana, Gustavo Henrique Ribeiro; de Pilla Varotti, Fernando 2013 2013-12-10 COMM-USE N PMC6269736 24335577.0 10.3390/molecules181215276 376hfuee 0.763744 Largo_2016, Abou-Hamdan_2018, Choudhury_2011, David_2013 Grazioso_2012, Thanigaimalai_2013, Opsenica_2011, Zhao_2016
62 Kumar_2014 1H-1,2,3-triazole tethered isatin-ferrocene conjugates: Synthesis and in vitro antimalarial evaluation Kumar, Kewal; Pradines, Bruno; Madamet, Marilyn; Amalvict, Rémy; Benoit, Nicolas; Kumar, Vipan 2014 2014-11-24 PMC N PMC7126053 25440881.0 10.1016/j.ejmech.2014.10.024 wc4xirpp 0.762319 Nisha_2014, Singh_2012, Dude_2008, Desai_2013 Grazioso_2012, Głowacka_2015, Chopade_2016, Cho_A_2012
63 Ma_D_2004 An efficient and tunable route to AG7088, a rhinovirus protease inhibitor Ma, Dawei; Xie, Weiqing; Zou, Bin; Lei, Qiong; Pei, Duanqing 2004 2004-10-18 PMC N PMC7111835 10.1016/j.tetlet.2004.08.179 m30w4o7d 0.758552 Lin_D_2012, MacDonald_2012, Rajić_2010, Thomson_2010 Prior_2013, Grazioso_2012, Pérez-Faginas_2011, Cho_A_2012
64 Lakshman_2012 Synthesis and Biological Properties of C-2 Triazolylinosine Derivatives Lakshman, Mahesh K.; Kumar, Amit; Balachandran, Raghavan; Day, Billy W.; Andrei, Graciela; Snoeck, Robert; Balzarini, Jan 2012 2012-07-03 PMC N PMC3427785 22758929.0 10.1021/jo300628y 0863gwzz 0.755872 Singh_2013, MacDonald_2012, Bouton_2017, Yoshizawa_2020, Yang_2008 Pomeisl_2019, Głowacka_2015, Tsoukala_2010, Carbone_2013
65 Torres_2010 Polycyclic N‐Benzamido Imides with Potent Activity against Vaccinia Virus Torres, Eva; Duque, María D.; Camps, Pelayo; Naesens, Lieve; Calvet, Teresa; Font‐Bardia, Mercè; Vázquez, Santiago 2010 2010-10-21 None N PMC7162373 20967819.0 10.1002/cmdc.201000306 lj6przme 0.754582 Naito_2007, Stork_2011, Berkhout_2006, Perrone_2015
66 Musella_2016 Identification of an indol-based derivative as potent and selective varicella zoster virus (VZV) inhibitor Musella, Simona; di Sarno, Veronica; Ciaglia, Tania; Sala, Marina; Spensiero, Antonia; Scala, Maria Carmina; Ostacolo, Carmine; Andrei, Graciela; Balzarini, Jan; Snoeck, Robert; Novellino, Ettore; Campiglia, Pietro; Bertamino, Alessia; Gomez-Monterrey, Isabel M. 2016 2016-11-29 PMC N PMC7115581 27639368.0 10.1016/j.ejmech.2016.09.014 gnnis7pl 0.753719 Meyerson_2017, Kang_2009, Stork_2011, Naito_2007, Pong_2011 Grazioso_2012, Lee_C_2019, Lin_J_2008, Opsenica_2011
67 Tanner_2005 The Adamantane-Derived Bananins Are Potent Inhibitors of the Helicase Activities and Replication of SARS Coronavirus Tanner, Julian A.; Zheng, Bo-Jian; Zhou, Jie; Watt, Rory M.; Jiang, Jie-Qing; Wong, Kin-Ling; Lin, Yong-Ping; Lu, Lin-Yu; He, Ming-Liang; Kung, Hsiang-Fu; Kesel, Andreas J.; Huang, Jian-Dong 2005 2005-03-31 None N PMC7110988 15797214.0 10.1016/j.chembiol.2005.01.006 3oiivkn2 0.753552 Volmer_2010, Kang_2009, Stork_2011, Vaughan_2012, Yang_2010 Kuo_C_2008, van_der_Linden_2014, Sidhu_1996, Opsenica_2011
68 Jansa_2012 An efficient microwave-assisted synthesis and biological properties of polysubstituted pyrimidinyl- and 1,3,5-triazinylphosphonic acids Jansa, Petr; Hradil, Ondřej; Baszczyňski, Ondřej; Dračínský, Martin; Klepetářová, Blanka; Holý, Antonín; Balzarini, Jan; Janeba, Zlatko 2012 2012-01-21 PMC N PMC7125588 10.1016/j.tet.2011.11.040 aqezkcyc 0.751499 MacDonald_2012, Yazarians_2017, Mohammat_2009, Nadaraia_2018, Bouton_2017 Chopade_2016, Głowacka_2015, Pomeisl_2019, Paramonova_2017, Tsoukala_2010
69 Singh_2010 Synthesis, structure–activity relationship and antiviral activity of 3′-N,N-dimethylamino-2′,3′-dideoxythymidine and its prodrugs Singh, Ramendra K.; Yadav, Dipti; Rai, Diwakar; Kumari, Garima; Pannecouque, C.; De Clercq, Erik 2010 2010-09-30 PMC N PMC7127469 20538384.0 10.1016/j.ejmech.2010.05.028 lz1qd69t 0.750867 Tallmadge_2008, Clapham_1991, Li_C_2013, Shen_2005, Yang_2010 Tsoukala_2010, Manta_2009, Piotrowska_2012
70 Piotrowska_2016 Novel isoxazolidine analogues of homonucleosides and homonucleotides Piotrowska, Dorota G.; Balzarini, Jan; Andrei, Graciela; Schols, Dominique; Snoeck, Robert; Wróblewski, Andrzej E.; Gotkowska, Joanna 2016 2016-12-15 PMC N PMC7111885 10.1016/j.tet.2016.10.073 8p0rp175 0.748211 MacDonald_2012, Mohammat_2009, Thomson_2010, Bouton_2017, Rajić_2010 Piotrowska_2019, Pomeisl_2019, Kokosza_2015, Głowacka_2015
71 Tardibono_2011 Enantioselective syntheses of carbocyclic nucleosides 5′-homocarbovir, epi-4′-homocarbovir, and their cyclopropylamine analogs using facially selective Pd-mediated allylations Tardibono, Lawrence P.; Miller, Marvin J.; Balzarini, Jan 2011 2011-02-04 None N PMC3050557 21399715.0 10.1016/j.tet.2010.11.097 jgbxupa4 0.745710 MacDonald_2012, Yazarians_2017, Kale_2010, Tayade_2015 Pomeisl_2019, Tsoukala_2010, Paramonova_2017
72 Song_2012 Synthesis and Biochemical Evaluation of Thiochromanone Thiosemicarbazone Analogues as Inhibitors of Cathepsin L Song, Jiangli; Jones, Lindsay\nM.; Kumar, G. D. Kishore; Conner, Elizabeth S.; Bayeh, Liela; Chavarria, Gustavo E.; Charlton-Sevcik, Amanda K.; Chen, Shen-En; Chaplin, David J.; Trawick, Mary Lynn; Pinney, Kevin G. 2012 2012-04-30 PMC N PMC4025852 24900494.0 10.1021/ml200299g qqhkc3f1 0.744948 Ramajayam_2010, Huixiong_Chen_1999, Yang_2010, Kishore_Kumar_2010 Kishore_Kumar_2010, Grazioso_2012, Sahoo_2016, Piotrowska_2019
73 Masahiko_1990 Inhibition of ribonucleotide reductase and growth of human colon carcinoma HT-29 cells and mouse leukemia L1210 cells by N-hydroxy-N′-aminoguanidine derivatives Masahiko, Matsumoto; Fox, John G.; Pou-Hsiung, Wang; Koneru, Phanesh B.; Lien, Eric J.; Cory, Joseph G. 1990 1990-10-15 PMC N PMC7157920 2242014.0 10.1016/0006-2952(90)90356-p rd4lxohp 0.744491 Zhang_2007, Bie_C_2016, Yang_2010, Brake_2008, Meng_2008 Deiab_2015, Mehellou_2010, Sticher_2020
74 Piotrowska_2017 Synthesis, anti-varicella-zoster virus and anti-cytomegalovirus activity of quinazoline-2,4-diones containing isoxazolidine and phosphonate substructures Piotrowska, Dorota G.; Andrei, Graciela; Schols, Dominique; Snoeck, Robert; Łysakowska, Magdalena 2017 2017-01-27 None N PMC7125519 27750154.0 10.1016/j.ejmech.2016.10.002 1sy2xvr6 0.739325 Rajić_2010, Yang_2010, Abou-Hamdan_2018, Largo_2016, Choudhury_2011 Kokosza_2015, Grabkowska-Drużyc_2018, Piotrowska_2019, Piotrowska_2016
75 Lin_D_2012 Improved synthesis of rupintrivir Lin, DaiZong; Qian, WangKe; Hilgenfeld, Rolf; Jiang, HuaLiang; Chen, KaiXian; Liu, Hong 2012 2012-01-04 PMC N PMC7088791 10.1007/s11426-011-4478-5 m76apsm1 0.738554 Schmidt_1982, Ma_D_2004, Shao_2008, Pérez-Faginas_2011 Kasthuri_2011, Chopade_2016, Ma_D_2004, Dude_2008
76 Egan_2004 Potent antiviral agent WIN 54954: high specific activity labelling with tritium Egan, Judith A.; Nugent, Richard P.; Filer, Crist N. 2004 2004-06-30 PMC N PMC7127203 15110350.0 10.1016/j.apradiso.2004.03.002 8dqniuzd 0.737666 Largo_2016, Abou-Hamdan_2018, Choudhury_2011, David_2013 Dude_2008
77 Tarui_2010 Diastereoselective synthesis of 2-fluoroaziridine-2-carboxylates by Reformatsky-type aza-Darzens reaction Tarui, Atsushi; Kawashima, Naoto; Sato, Kazuyuki; Omote, Masaaki; Ando, Akira 2010 2010-08-11 PMC N PMC7111781 10.1016/j.tetlet.2010.06.030 zeqdsyxt 0.736018 MacDonald_2012, Yazarians_2017, Tayade_2015, Zhao_2017 Pomeisl_2019, Thomson_2010, Tayade_2015, Paramonova_2017
78 Rajić_2018 Asymmetric Primaquine and Halogenaniline Fumardiamides as Novel Biologically Active Michael Acceptors Rajić, Zrinka; Beus, Maja; Michnová, Hana; Vlainić, Josipa; Persoons, Leentje; Kosalec, Ivan; Jampílek, Josef; Schols, Dominique; Keser, Toma; Zorc, Branka 2018 2018-07-14 COMM-USE N PMC6100582 30011922.0 10.3390/molecules23071724 s206vrtg 0.733693 Choudhury_2011, Abou-Hamdan_2018, David_2013, Largo_2016, Yang_2010 Piotrowska_2019, Grazioso_2012, Hamada_2013, Carbone_2013
79 Huang_2015 Inhibition of a Putative Dihydropyrimidinase from Pseudomonas aeruginosa PAO1 by Flavonoids and Substrates of Cyclic Amidohydrolases Huang, Cheng-Yang 2015 2015-05-19 COMM-USE N PMC4437985 25993634.0 10.1371/journal.pone.0127634 n5w88l23 0.730165 Blank_2017, Smith_2003, Gorbalenya_1988, Yang_2010, Wang_2007 Grazioso_2012, Zhao_2016, Opsenica_2011, Yoshida_2019
80 Yadav_2005 Synthesis of 4-hydroxy-1-methylindole and benzo[b]thiophen-4-ol based unnatural flavonoids as new class of antimicrobial agents Yadav, Prem P.; Gupta, Prasoon; Chaturvedi, A.K.; Shukla, P.K.; Maurya, Rakesh 2005 2005-03-01 PMC N PMC7125744 15698765.0 10.1016/j.bmc.2004.12.032 hyxj4vgo 0.728736 Kuo_R_2009, Nadaraia_2018, Xu_X_2016, Desai_2013 Paramonova_2017, Grazioso_2012, Tayade_2015
81 Pomarnacka_2011 Synthesis, Cytotoxicity Testing, and Structure–Activity Relationships of Novel 6‐Chloro‐7‐(4‐phenylimino‐4H‐3,1‐benzoxazin‐2‐yl)‐3‐(substituted)‐1,4,2‐benzodithiazine 1,1‐dioxides Pomarnacka, Elżbieta; Kornicka, Anita; Kuchnio, Anna; Heinrichs, Maike; Grünert, Renate; Gdaniec, Maria; Bednarski, Patrick J. 2011 2011-05-25 PMC N PMC7159733 21618270.0 10.1002/ardp.201000183 ahsyp92n 0.725359 Callison_1999, Volmer_2010, Qi_Z_2018, Wu_G_2005, Chang_2011
82 Ighilahriz-Boubchir_2017 Recyclable Keggin Heteropolyacids as an Environmentally Benign Catalyst for the Synthesis of New 2-Benzoylamino-N-phenyl-benzamide Derivatives under Microwave Irradiations at Solvent-Free Conditions and the Evaluation of Biological Activity Ighilahriz-Boubchir, Karima; Boutemeur-Kheddis, Baya; Rabia, Cherifa; Makhloufi-Chebli, Malika; Hamdi, Maamar; Silva, Artur M. S. 2017 2017-12-21 COMM-USE N PMC5943967 29267237.0 10.3390/molecules23010008 h8l7zp2b 0.723408 Mohammat_2009, MacDonald_2012, Abou-Hamdan_2018, Largo_2016, Choudhury_2011 Pahonțu_2015, Yang_2010, Pomeisl_2019, Thomson_2010
83 Balzarini_2006 Inhibition of feline (FIPV) and human (SARS) coronavirus by semisynthetic derivatives of glycopeptide antibiotics Balzarini, Jan; Keyaerts, Els; Vijgen, Leen; Egberink, Herman; De Clercq, Erik; Van Ranst, Marc; Printsevskaya, Svetlana S.; Olsufyeva, Eugenia N.; Solovieva, Svetlana E.; Preobrazhenskaya, Maria N. 2006 2006-10-31 PMC N PMC7114212 16675038.0 10.1016/j.antiviral.2006.03.005 ivuemc2j 0.721673 Tallmadge_2008, Jiang_2006, Naito_2007, Compton_2014, Yasui_2016 Hsieh_2010, Wu_H_2016, Sidhu_1996
84 Yuan_2019 Synthetic surfactin analogues have improved anti-PEDV properties Yuan, Lvfeng; Zhang, Shuai; Peng, Jie; Li, Yuchen; Yang, Qian 2019 2019-04-11 COMM-USE N PMC6459484 30973929.0 10.1371/journal.pone.0215227 m0wodqr3 0.720222 Berkhout_2006, Volmer_2010, Naito_2007, Xu_Z_2012, Kang_2009 Lee_C_2019, Wang_2014, Zhu_X_2015, Sidhu_1996
85 Kim_J_2019 Slow-Binding Inhibition of Tyrosinase by Ecklonia cava Phlorotannins Kim, Jang Hoon; Lee, Sunggun; Park, Saerom; Park, Ji Soo; Kim, Young Ho; Yang, Seo Young 2019 2019-06-16 COMM-USE N PMC6627058 31208149.0 10.3390/md17060359 mzmzyf4p 0.719414 Largo_2016, Abou-Hamdan_2018, Choudhury_2011, David_2013, Yang_2010 Park_2017, Kim_J_2019, Yoshida_2019, Li_X_2019
86 Romero_2015 Optimization of xanthatin extraction from Xanthium spinosum L. and its cytotoxic, anti-angiogenesis and antiviral properties Romero, M.; Zanuy, M.; Rosell, E.; Cascante, M.; Piulats, J.; Font-Bardia, M.; Balzarini, J.; De Clerq, E.; Pujol, M.D. 2015 2015-01-27 PMC N PMC7115430 25481815.0 10.1016/j.ejmech.2014.11.060 b4kiojxb 0.717727 Zhang_2007, Bie_C_2016, Berkhout_2006, Desai_2013 Lee_C_2020, Xie_J_2018, Adnan_2019, Park_2017
87 Havrylyuk_2013 Synthesis and biological activity evaluation of 5-pyrazoline substituted 4-thiazolidinones Havrylyuk, Dmytro; Zimenkovsky, Borys; Vasylenko, Olexandr; Day, Craig W.; Smee, Donald F.; Grellier, Philippe; Lesyk, Roman 2013 2013-08-31 PMC N PMC7115615 23811085.0 10.1016/j.ejmech.2013.05.044 04xr5xdl 0.710696 Naito_2007, Liu_Y_2008, Berkhout_2006, Shen_2005, Volmer_2010 Sahoo_2016, Kumarasamy_2017, Grazioso_2012, Carbone_2013
88 Mohammed_2019 Synthesis and anti-HSV activity of tricyclic penciclovir and hydroxybutylguanine derivatives Mohammed, Anber F.; Andrei, Graciela; Hayallah, Alaa M.; Abdel-Moty, Samia G.; Snoeck, Robert; Simons, Claire 2019 2019-03-15 PMC N PMC7126098 30738653.0 10.1016/j.bmc.2019.02.005 feo4e6gi 0.708858 Naito_2007, Tallmadge_2008, Ban_J_2018, Torres_2012, Yang_2010 Ren_Z_2010, Wang_2014, Sidhu_1996, Piotrowska_2019
89 Camps_2008 Synthesis and pharmacological evaluation of several ring-contracted amantadine analogs Camps, Pelayo; Duque, María D.; Vázquez, Santiago; Naesens, Lieve; Clercq, Erik De; Sureda, Francesc X.; López-Querol, Marta; Camins, Antoni; Pallàs, Mercè; Prathalingam, S. Radhika; Kelly, John M.; Romero, Vanessa; Ivorra, Dolores; Cortés, Diego 2008 2008-12-01 PMC N PMC7125889 18954995.0 10.1016/j.bmc.2008.10.028 4wcsz4is 0.708854 Naito_2007, Berkhout_2006, Volmer_2010, Torres_2012, Haasnoot_2010 Duque_2009, Pérez-Faginas_2011, Głowacka_2015, Grazioso_2012
90 Yazarians_2017 A regioselective etherification of pyridoxine via an ortho-pyridinone methide intermediate Yazarians, Jessica A.; Jiménez, Brian L.; Boyce, Gregory R. 2017 2017-06-07 PMC N PMC7111860 10.1016/j.tetlet.2017.04.082 c5l2r3kj 0.707733 MacDonald_2012, Kale_2010, Tayade_2015, Tarui_2010 Lin_Z_2012, Tayade_2015, Paramonova_2017, Sobenina_2018
91 Kang_2016 First discovery of novel 3-hydroxy-quinazoline-2,4(1H,3H)-diones as specific anti-vaccinia and adenovirus agents via ‘privileged scaffold’ refining approach Kang, Dongwei; Zhang, Heng; Zhou, Zhongxia; Huang, Boshi; Naesens, Lieve; Zhan, Peng; Liu, Xinyong 2016 2016-11-01 PMC N PMC7126219 27742238.0 10.1016/j.bmcl.2016.09.071 8yhsjbmi 0.706622 Naito_2007, Berkhout_2006, Liu_Y_2008, Brake_2008, Tsai_2013 Grazioso_2012, Tsoukala_2010, Piotrowska_2012, Głowacka_2015
92 Regnier_2009 New developments for the design, synthesis and biological evaluation of potent SARS-CoV 3CLpro inhibitors Regnier, Thomas; Sarma, Diganta; Hidaka, Koushi; Bacha, Usman; Freire, Ernesto; Hayashi, Yoshio; Kiso, Yoshiaki 2009 2009-05-15 None N PMC4436079 19362479.0 10.1016/j.bmcl.2009.03.118 zxganumj 0.706030 Ramajayam_2010, Ramajayam_2010, Chen_2005, Konno_2016 Ramajayam_2010, Konno_2017, Konno_2013, Konno_2016
93 Kumar_2010 Benzylidene/2-chlorobenzylidene hydrazides: Synthesis, antimicrobial activity, QSAR studies and antiviral evaluation Kumar, Davinder; Judge, Vikramjeet; Narang, Rakesh; Sangwan, Sonia; De Clercq, Erik; Balzarini, Jan; Narasimhan, Balasubramanian 2010 2010-07-31 PMC N PMC7127590 20347509.0 10.1016/j.ejmech.2010.03.002 e1sz07u3 0.705933 Naito_2007, Qi_Z_2018, Berkhout_2006, Zakaryan_2017 Sahoo_2016, Cihan-Üstündağ_2019, Grazioso_2012, Desai_2013
94 Głowacka_2017 Design, Synthesis, and the Biological Evaluation of a New Series of Acyclic 1,2,3‐Triazole Nucleosides Głowacka, Iwona E.; Andrei, Graciela; Schols, Dominique; Snoeck, Robert; Gawron, Katarzyna 2017 2017-08-01 PMC N PMC7161868 28763115.0 10.1002/ardp.201700166 wxcn28ws 0.701823 Abou-Hamdan_2018, Choudhury_2011, David_2013, Largo_2016, Yang_2010
95 Ghosh_2009 Structure-Based Design, Synthesis, and Biological Evaluation of a Series of Novel and Reversible Inhibitors for the Severe Acute Respiratory Syndrome-Coronavirus Papain-Like Protease Ghosh, Arun K.; Takayama, Jun; Aubin, Yoann; Ratia, Kiira; Chaudhuri, Rima; Baez, Yahira; Sleeman, Katrina; Coughlin, Melissa; Nichols, Daniel B.; Mulhearn, Debbie C.; Prabhakar, Bellur S.; Baker, Susan C.; Johnson, Michael E.; Mesecar, Andrew D. 2009 2009-08-27 PMC N PMC3148848 19645480.0 10.1021/jm900611t mmqlwsye 0.701389 Naito_2007, Pong_2011, Zhang_2004, Kang_2009, Stork_2011 Thanigaimalai_2013, Thanigaimalai_2013, Konno_2013, Báez-Santos_2014
96 Bessières_2018 Highly convergent synthesis and antiviral activity of (E)-but-2-enyl nucleoside phosphonoamidates Bessières, Maxime; Hervin, Vincent; Roy, Vincent; Chartier, Agnès; Snoeck, Robert; Andrei, Graciela; Lohier, Jean-François; Agrofoglio, Luigi A. 2018 2018-02-25 PMC N PMC7115695 29407990.0 10.1016/j.ejmech.2018.01.086 zj5fx2q5 0.699403 Naito_2007, Stork_2011, Rice_1992, Armesto_2007, Keep_2014 Grazioso_2012, Cho_A_2012, Hamada_2013, Hocková_2011
97 Siebert_2018 Synthesis and antimicrobial activity of amino acid and peptide derivatives of mycophenolic acid Siebert, Agnieszka; Wysocka, Magdalena; Krawczyk, Beata; Cholewiński, Grzegorz; Rachoń, Janusz 2018 2018-01-01 PMC N 29216563.0 10.1016/j.ejmech.2017.11.094 wydc0wyd 0.697598 Hsueh_2005, Hsueh_2005, Souto_2016, El-Seedy_2016
98 Yadav_2010 4-[1-(Substituted aryl/alkyl carbonyl)-benzoimidazol-2-yl]-benzenesulfonic acids: Synthesis, antimicrobial activity, QSAR studies, and antiviral evaluation Yadav, Snehlata; Kumar, Pradeep; De Clercq, Erik; Balzarini, Jan; Pannecouque, Christophe; Dewan, Sharwan Kumar; Narasimhan, Balasubramanian 2010 2010-12-31 PMC N PMC7115694 20971531.0 10.1016/j.ejmech.2010.09.065 6jffpajp 0.696553 Qi_Z_2018, Saw_A_2019, Liao_2006, Dai_Q_2012, Abou-Hamdan_2018 Kumar_2014, Lakshman_2014, Sahoo_2016, Pomeisl_2019
99 Thanigaimalai_2013 Development of potent dipeptide-type SARS-CoV 3CL protease inhibitors with novel P3 scaffolds: Design, synthesis, biological evaluation, and docking studies Thanigaimalai, Pillaiyar; Konno, Sho; Yamamoto, Takehito; Koiwai, Yuji; Taguchi, Akihiro; Takayama, Kentaro; Yakushiji, Fumika; Akaji, Kenichi; Chen, Shen-En; Naser-Tavakolian, Aurash; Schön, Arne; Freire, Ernesto; Hayashi, Yoshio 2013 2013-10-31 None N PMC7115411 23994330.0 10.1016/j.ejmech.2013.07.037 olfpcndb 0.694252 Yang_2010, Callison_1999, Tosoni_2015, Naito_2007, Jendrach_2014 Konno_2013, Thanigaimalai_2013, Niu_C_2008, Grazioso_2012
100 Bankowska_2014 Design, synthesis, antiviral and cytotoxic evaluation of novel acyclic phosphonate nucleotide analogues with a 5,6-dihydro-1H-[1,2,3]triazolo[4,5-d]pyridazine-4,7-dione system Bankowska, Emilia; Balzarini, Jan; Głowacka, Iwona E.; Wróblewski, Andrzej E. 2014 2014-01-25 PMC N PMC4494773 26166892.0 10.1007/s00706-013-1137-x 0xb02y2e 0.694160 David_2013, Choudhury_2011, Abou-Hamdan_2018, Largo_2016, Gogineni_2015 Pomeisl_2019, Głowacka_2015, Tsoukala_2010, Piotrowska_2012
101 Tabuchi_2009 Preparation of novel (Z)-4-ylidenebenzo[b]furo[3,2-d][1,3]oxazines and their biological activity Tabuchi, Yukako; Ando, Yuko; Kanemura, Hidemi; Kawasaki, Ikuo; Ohishi, Takahiro; Koida, Masao; Fukuyama, Ryo; Nakamuta, Hiromichi; Ohta, Shunsaku; Nishide, Kiyoharu; Ohishi, Yoshitaka 2009 2009-06-01 None N PMC7127799 19406645.0 10.1016/j.bmc.2009.04.017 46mslzwr 0.693261 Rajić_2010, Zhang_2007, Desai_2013, Largo_2016 Pomeisl_2019, Pahonțu_2015, Lakshman_2014, Tsoukala_2010
102 Yang_2008 Synthesis of N-methyl-d-ribopyranuronamide nucleosides Yang, Shiqiong; Busson, Roger; Herdewijn, Piet 2008 2008-10-20 PMC N PMC7126205 10.1016/j.tet.2008.08.027 8dpd2fxx 0.691949 Bouton_2017, Yazarians_2017, Zhao_2017, Yoshizawa_2020 Kumarapperuma_2007, Kasthuri_2011, Pomeisl_2019, Tsoukala_2010
103 Park_2012 Synthesis and antiviral evaluation of 7-O-arylmethylquercetin derivatives against SARS-associated coronavirus (SCV) and hepatitis C virus (HCV) Park, Hye Ri; Yoon, Hyunjun; Kim, Mi Kyoung; Lee, Sung Dae; Chong, Youhoon 2012 2012-02-02 PMC N PMC7090976 22297745.0 10.1007/s12272-012-0108-9 59bqlc5y 0.686593 Kang_2009, Naito_2007, Volmer_2010, Meyerson_2017, Ban_J_2018 Grazioso_2012, Ikejiri_2007, Kim_M_2011, Zhong_2015
104 Dell'Isola_2014 Synthesis and Antiviral Properties of Spirocyclic [1,2,3]‐Triazolooxazine Nucleosides Dell'Isola, Antonio; McLachlan, Matthew M. W.; Neuman, Benjamin W.; Al‐Mullah, Hawaa M. N.; Binks, Alexander W. D.; Elvidge, Warren; Shankland, Kenneth; Cobb, Alexander J. A. 2014 2014-09-08 None N PMC7162048 25082061.0 10.1002/chem.201403560 1mloqfqu 0.686323 MacDonald_2012, Yazarians_2017, Bouton_2017, Mohammat_2009
105 Singh_2013 Regioselective synthesis of 6-substituted-2-amino-5-bromo-4(3H)-pyrimidinones and evaluation of their antiviral activity Singh, Kamaljit; Singh, Kawaljit; Balzarini, Jan 2013 2013-09-30 PMC N PMC7127258 23911856.0 10.1016/j.ejmech.2013.06.036 7dxtqde5 0.685827 Wu_G_2005, Naito_2007, Callison_1999, Volmer_2010 Paramonova_2017, Pomeisl_2019, Tayade_2015, Głowacka_2015
106 Sokolova_2013 New quaternary ammonium camphor derivatives and their antiviral activity, genotoxic effects and cytotoxicity Sokolova, Anastasiya S.; Yarovaya, Оlga I.; Shernyukov, Аndrey V.; Pokrovsky, Мichail A.; Pokrovsky, Аndrey G.; Lavrinenko, Valentina A.; Zarubaev, Vladimir V.; Tretiak, Tatiana S.; Anfimov, Pavel M.; Kiselev, Oleg I.; Beklemishev, Anatoly B.; Salakhutdinov, Nariman F. 2013 2013-11-01 PMC N PMC7126328 23993669.0 10.1016/j.bmc.2013.08.014 2kytuxxy 0.681405 Volmer_2010, Callison_1999, Naito_2007, Berkhout_2006, Perrone_2015 Grazioso_2012, Sahoo_2016, Cao_Z_2013, Gazivoda_2008
107 Druzhyna_2016 Screening of a composite library of clinically used drugs and well-characterized pharmacological compounds for cystathionine β-synthase inhibition identifies benserazide as a drug potentially suitable for repurposing for the experimental therapy of colon cancer Druzhyna, Nadiya; Szczesny, Bartosz; Olah, Gabor; Módis, Katalin; Asimakopoulou, Antonia; Pavlidou, Athanasia; Szoleczky, Petra; Gerö, Domokos; Yanagi, Kazunori; Törö, Gabor; López-García, Isabel; Myrianthopoulos, Vassilios; Mikros, Emmanuel; Zatarain, John R.; Chao, Celia; Papapetropoulos, Andreas; Hellmich, Mark R.; Szabo, Csaba 2016 2016-11-30 None N PMC5107130 27521834.0 10.1016/j.phrs.2016.08.016 bimkggvg 0.680964 Zhang_2007, Bie_C_2016, Grujić_2002, Zhao_2013, Yang_2010 Grazioso_2012, Zhao_2016, Opsenica_2011
108 Torres_2012 Synthesis of benzopolycyclic cage amines: NMDA receptor antagonist, trypanocidal and antiviral activities Torres, Eva; Duque, María D.; López-Querol, Marta; Taylor, Martin C.; Naesens, Lieve; Ma, Chunlong; Pinto, Lawrence H.; Sureda, Francesc X.; Kelly, John M.; Vázquez, Santiago 2012 2012-01-15 None N PMC3353318 22178660.0 10.1016/j.bmc.2011.11.050 088gqxyz 0.677320 Greene_2012, Kumar_2016, Ban_J_2018, Meyerson_2017 Grazioso_2012, Pérez-Faginas_2011, Cho_A_2012, Głowacka_2015
109 Tichý_2011 New prodrugs of Adefovir and Cidofovir Tichý, Tomáš; Andrei, Graciela; Dračínský, Martin; Holý, Antonín; Balzarini, Jan; Snoeck, Robert; Krečmerová, Marcela 2011 2011-06-01 PMC N PMC7127853 21565516.0 10.1016/j.bmc.2011.04.016 om542ku5 0.677067 Tallmadge_2008, De_Clercq_2007, Crowe_2014, Ryu_W_2017, Yasui_2016 Krečmerová_2017, Piotrowska_2019, Hamada_2013, Szűcs_2018
110 Khandaker_2019 Synthesis and Evaluations of “1,4‐Triazolyl Combretacoumarins” and Desmethoxy Analogs Khandaker, Tashrique A.; Hess, Jessica D.; Aguilera, Renato; Andrei, Graciela; Snoeck, Robert; Schols, Dominique; Pradhan, Padmanava; Lakshman, Mahesh K. 2019 2019-08-07 PMC N PMC6774347 31579393.0 10.1002/ejoc.201900569 90pat7ij 0.676489 Jiang_2011, Brake_2008, Callison_1999, Qi_Z_2018, Saw_A_2019
111 Lakshman_2014 Facile synthesis of 1-alkoxy-1H-benzo- and 7-azabenzotriazoles from peptide coupling agents, mechanistic studies, and synthetic applications Lakshman, Mahesh K; Singh, Manish K; Kumar, Mukesh; Chamala, Raghu Ram; Yedulla, Vijayender R; Wagner, Domenick; Leung, Evan; Yang, Lijia; Matin, Asha; Ahmad, Sadia 2014 2014-08-19 None N PMC4168895 25246951.0 10.3762/bjoc.10.200 9j7tumcf 0.676223 MacDonald_2012, Yazarians_2017, Mohammat_2009, Zhao_2017, Lee_C_2014 Pomeisl_2019, Tsoukala_2010, Głowacka_2015, Bankowska_2014
112 Baszczyňski_2018 Xanthine-based acyclic nucleoside phosphonates with potent antiviral activity against varicella-zoster virus and human cytomegalovirus Baszczyňski, Ondřej; Kaiser, Martin Maxmilian; Česnek, Michal; Břehová, Petra; Jansa, Petr; Procházková, Eliška; Dračínský, Martin; Snoeck, Robert; Andrei, Graciela; Janeba, Zlatko 2018 2018-11-29 NONCOMM N PMC6287304 30497281.0 10.1177/2040206618813050 hdpanetr 0.672348 Stork_2011, Kang_2009, Pong_2011, Meyerson_2017, Naito_2007 Krečmerová_2017, de_Clercq_1991, Hamada_2013, Mehellou_2010
113 Jansa_2014 5-Substituted 2-amino-4,6-dihydroxypyrimidines and 2-amino-4,6-dichloropyrimidines: synthesis and inhibitory effects on immune-activated nitric oxide production Jansa, Petr; Holý, Antonín; Dračínský, Martin; Kolman, Viktor; Janeba, Zlatko; Kostecká, Petra; Kmoníčková, Eva; Zídek, Zdeněk 2014 2014-05-09 PMC N PMC7080047 10.1007/s00044-014-1018-9 kwehwh61 0.670994 Singh_2013, Jiang_2011, Lenstra_1988, Mohammat_2009, Brake_2008 Tsoukala_2010, Manta_2009, Pomeisl_2019
114 Balzarini_2014 Structural Analogs of Umifenovir. 1. Synthesis and Biological Activity of Ethyl 5-Hydroxy-1-Methyl-2-(Trans-2-Phenylcyclopropyl)-1H-Indole-3-Carboxylate Balzarini, J.; Ruchko, E. A.; Zakharova, E. K.; Kameneva, I. Yu.; Nawrozkij, M. B. 2014 2014-06-08 PMC N PMC7088350 10.1007/s10593-014-1499-y 2yhj3m9i 0.670693 Kale_2010, Lin_Z_2012, Marcotullio_2014, Siridechadilok_2013 Kumarapperuma_2007, Paramonova_2017, Duque_2009, Głowacka_2015
115 Paramonova_2017 Novel 1-[5-(4-bromophenoxy)pentyl]-3-(2-arylamino- 2-oxoethyl)uracils and their antiviral properties Paramonova, Maria P.; Khandazhinskaya, Anastasia L.; Seley-Radtke, Katherine L.; Novikov, Mikhail S. 2017 2017-02-28 PMC N 10.1016/j.mencom.2017.01.027 sfl5nrc4 0.669539 Polverino_2017, Singh_2013, Mohammat_2009, Jiang_2011 Riahi_2009, Tayade_2015, Mohammat_2009, Novikov_2013
116 Chopade_2016 A synthesis of (±)-thia-calanolide A, its resolution and in vitro biological evaluation Chopade, Anil U.; Chopade, Manojkumar U.; Chanda, Bhanu M.; Sawaikar, Dilip D.; Sonawane, Kiran B.; Gurjar, Mukund K. 2016 2016-11-30 PMC N PMC7148711 10.1016/j.arabjc.2012.04.027 05fqdmei 0.667921 Lenstra_1988, Qi_Z_2018, Jendrach_2014, Dai_Q_2012, Saw_A_2019 Tayade_2015, Pomeisl_2019, Grazioso_2012, Kasthuri_2011
117 Novikov_2011 1-[2-(2-Benzoyl- and 2-benzylphenoxy)ethyl]uracils as potent anti-HIV-1 agents Novikov, Mikhail S.; Ivanova, Olga N.; Ivanov, Alexander V.; Ozerov, Alexander A.; Valuev-Elliston, Vladimir T.; Temburnikar, Kartik; Gurskaya, Galina V.; Kochetkov, Sergey N.; Pannecouque, Christophe; Balzarini, Jan; Seley-Radtke, Katherine L. 2011 2011-10-01 PMC N PMC7127633 21903401.0 10.1016/j.bmc.2011.08.025 1nk1trsa 0.667622 Naito_2007, Liu_Y_2008, Magden_2004, Stork_2011 Grazioso_2012, Głowacka_2015, Paramonova_2017, Tsoukala_2010
118 Bari_2020 Design and syntheses of 7-nitro-2-aryl-4H-benzo[d][1,3]oxazin-4-ones as potent anticancer and antioxidant agents Bari, Ayesha; Khan, Zulfiqar Ali; Shahzad, Sohail Anjum; Raza Naqvi, Syed Ali; Khan, Shakeel Ahmad; Amjad, Hira; Iqbal, Ahsan; Yar, Muhammad 2020 2020-08-15 PMC N 10.1016/j.molstruc.2020.128252 bow6mfsd 0.667122 Desai_2013, Zhang_2007, Choudhury_2011, Abou-Hamdan_2018 Grazioso_2012, Tsoukala_2010, Sahoo_2016, Kumar_2014
119 Kong_2008 Natural product juglone targets three key enzymes from Helicobacter pylori: inhibition assay with crystal structure characterization Kong, Yun-hua; Zhang, Liang; Yang, Zheng-yi; Han, Cong; Hu, Li-hong; Jiang, Hua-liang; Shen, Xu 2008 2008-07-23 PMC N PMC7091819 18565285.0 10.1111/j.1745-7254.2008.00808.x cgw2okh8 0.667102 Yang_2010, Smith_2003, Gendron_2010, Blank_2017, Kang_2009 Grazioso_2012, Xie_J_2018, Xing_2014
120 Szűcs_2018 Structure-activity relationship studies of lipophilic teicoplanin pseudoaglycon derivatives as new anti-influenza virus agents Szűcs, Zsolt; Kelemen, Viktor; Le Thai, Son; Csávás, Magdolna; Rőth, Erzsébet; Batta, Gyula; Stevaert, Annelies; Vanderlinden, Evelien; Naesens, Lieve; Herczegh, Pál; Borbás, Anikó 2018 2018-09-05 None N PMC7115582 30170320.0 10.1016/j.ejmech.2018.08.058 wclwpq7v 0.660597 Naito_2007, Singh_2013, Callison_1999, Yang_2012 Grazioso_2012, Sarkar_2013, McGuigan_2013, Mehellou_2010
121 Karaküçük-İyidoğan_2019 Synthesis, Biological Evaluation and Ligand Based Pharmacophore Modeling of New Aromatic Thiosemicarbazones as Potential Anticancer Agents Karaküçük-İyidoğan, A.; Aydınöz, B.; Taşkın-Tok, T.; Oruç-Emre, E. E.; Balzarini, J. 2019 2019-05-15 PMC N PMC7089137 10.1007/s11094-019-01968-3 jyti99xq 0.658194 Naito_2007, Brake_2008, Volmer_2010, Berkhout_2006, Callison_1999 Piotrowska_2019, Sahoo_2016, Hamada_2013, McGuigan_2013
122 Liang_2019 Synthesis and structure-activity relationship studies of water-soluble β-cyclodextrin-glycyrrhetinic acid conjugates as potential anti-influenza virus agents Liang, Shuobin; Li, Man; Yu, Xiaojuan; Jin, Hongwei; Zhang, Yongmin; Zhang, Lihe; Zhou, Demin; Xiao, Sulong 2019 2019-03-15 None N PMC7115653 30731401.0 10.1016/j.ejmech.2019.01.074 edinv5ou 0.657166 Naito_2007, Volmer_2010, Berkhout_2006, Kang_2009, Stork_2011 Grazioso_2012, Szűcs_2018, Sarkar_2013, Mehellou_2010
123 Qi_Y_2012 In vitro anti-hepatitis B and SARS virus activities of a titanium-substituted-heteropolytungstate Qi, Yan-fei; Zhang, Hong; Wang, Juan; Jiang, Yanfang; Li, Jinhua; Yuan, Ye; Zhang, Shiyao; Xu, Kun; Li, Yangguang; Li, Juan; Niu, Junqi; Wang, Enbo 2012 2012-01-31 PMC N PMC7114352 22127069.0 10.1016/j.antiviral.2011.11.003 5hcb15xc 0.656942 Tallmadge_2008, Liu_H_2009, Meng_2008, Kang_2009, Aweya_2015 Zhang_2012, Zhou_2012, Zhong_2009, Wang_2014
124 Zhong_2017 Synthesis and biological activity of myricetin derivatives containing 1,3,4-thiadiazole scaffold Zhong, Xinmin; Wang, Xiaobin; Chen, Lijuan; Ruan, Xianghui; Li, Qin; Zhang, Juping; Chen, Zhuo; Xue, Wei 2017 2017-10-17 COMM-USE N PMC5645266 29086886.0 10.1186/s13065-017-0336-7 af55iah5 0.652495 Choudhury_2011, David_2013, Abou-Hamdan_2018, Largo_2016, Kuo_R_2009 Sahoo_2016, Bozorov_2019, Głowacka_2015, Głowacka_2016
125 Pileggi_2018 Expedient synthesis and biological evaluation of alkenyl acyclic nucleoside phosphonate prodrugs Pileggi, Elisa; Serpi, Michaela; Andrei, Graciela; Schols, Dominique; Snoeck, Robert; Pertusati, Fabrizio 2018 2018-07-23 None N PMC7126595 29880251.0 10.1016/j.bmc.2018.05.034 c82kjcoy 0.648717 MacDonald_2012, Stork_2011, Bouton_2017, Naito_2007 McGuigan_2013, Krečmerová_2017, Mehellou_2010, Hamada_2013
126 Kang_2015 Jubanines F–J, cyclopeptide alkaloids from the roots of Ziziphus jujuba Kang, Kyo Bin; Ming, Gao; Kim, Geum Jin; Ha, Thi-Kim-Quy; Choi, Hyukjae; Oh, Won Keun; Sung, Sang Hyun 2015 2015-11-30 PMC N PMC7111685 26361730.0 10.1016/j.phytochem.2015.09.001 lib3slrw 0.648213 Choudhury_2011, David_2013, Abou-Hamdan_2018, Largo_2016, Huggett_2007 Lee_C_2020, Li_X_2019, Xie_J_2018, Shashidhar_2013
127 Lee_C_2009 Investigation of the pharmacophore space of Severe Acute Respiratory Syndrome coronavirus (SARS-CoV) NTPase/helicase by dihydroxychromone derivatives Lee, Chaewoon; Lee, Jin Moo; Lee, Na-Ra; Kim, Dong-Eun; Jeong, Yong-Joo; Chong, Youhoon 2009 2009-08-15 PMC N PMC7127646 19625187.0 10.1016/j.bmcl.2009.07.009 texnuvvp 0.645748 Naito_2007, Ivarsson_2012, Liao_2006, Pong_2011, Wang_2014 Verschueren_2008, Xia_B_2011, Kao_R_2004
128 Thanigaimalai_2013 Design, synthesis, and biological evaluation of novel dipeptide-type SARS-CoV 3CL protease inhibitors: Structure–activity relationship study Thanigaimalai, Pillaiyar; Konno, Sho; Yamamoto, Takehito; Koiwai, Yuji; Taguchi, Akihiro; Takayama, Kentaro; Yakushiji, Fumika; Akaji, Kenichi; Kiso, Yoshiaki; Kawasaki, Yuko; Chen, Shen-En; Naser-Tavakolian, Aurash; Schön, Arne; Freire, Ernesto; Hayashi, Yoshio 2013 2013-07-31 None N PMC7115367 23747811.0 10.1016/j.ejmech.2013.05.005 2i6795ga 0.643987 Yang_2010, Vaughan_2012, Smith_2003, Ramajayam_2010, Naito_2007 Thanigaimalai_2013, Konno_2013, Niu_C_2008
129 Taghizadeh_2019 Assessment of in vitro bioactivities of Pis v 1 (2S albumin) and Pis v 2.0101 (11S globulin) proteins derived from pistachio (Pistacia vera L.) Taghizadeh, Seyedeh Faezeh; Rezaee, Ramin; Mehmandoust, Masoumeh; Badibostan, Hasan; Karimi, Gholamreza 2019 2019-12-24 PMC N PMC7149036 10.1007/s11694-019-00355-6 ulqjpj1j 0.642287 Choudhury_2011, Abou-Hamdan_2018, David_2013, Largo_2016, Okda_2017 Liu_Z_2013, Cheng_2014, Zhao_2016, Zhong_2009
130 Nisha_2014 N-Propargylated isatin-Mannich mono- and bis-adducts: Synthesis and preliminary analysis of in vitro activity against Tritrichomonas foetus Nisha, ; Kumar, Kewal; Bhargava, Gaurav; Land, Kirkwood M.; Chang, Kai-Hsiang; Arora, Reena; Sen, Somdutta; Kumar, Vipan 2014 2014-03-03 PMC N PMC7115568 24561663.0 10.1016/j.ejmech.2014.01.015 hzfawetp 0.641537 Zhang_2007, Bie_C_2016, Berkhout_2006, Shen_2005 Grazioso_2012, Kumar_2014, Raj_R_2014, Chopade_2016
131 Gürsoy_2020 Design and synthesis of novel Imidazo[2,1-b]thiazole derivatives as potent antiviral and antimycobacterial agents Gürsoy, Elif; Dincel, Efe Doğukan; Naesens, Lieve; Ulusoy Güzeldemirci, Nuray 2020 2020-01-31 PMC N PMC7112121 31862455.0 10.1016/j.bioorg.2019.103496 c4wnr5xe 0.635919 Naito_2007, Tallmadge_2008, Berkhout_2006, Liu_Y_2008 Grazioso_2012, Hamada_2013, Cihan-Üstündağ_2019, Zhao_2016
132 Baltina_2015 Glycyrrhizic acid derivatives as influenza A/H1N1 virus inhibitors Baltina, Lidia A.; Zarubaev, Vladimir V.; Baltina, Lia A.; Orshanskaya, Iana A.; Fairushina, Alina I.; Kiselev, Oleg I.; Yunusov, Marat S. 2015 2015-04-15 PMC N PMC7127794 25801933.0 10.1016/j.bmcl.2015.02.074 d6do1xad 0.634298 Schmidt_1982, Lin_D_2012, Yang_2010, Schlesinger_1983 Lin_J_2008, Chang_2013, Zhu_X_2015, Pérez-Faginas_2011
133 Torres_2014 Azapropellanes with Anti-Influenza A Virus Activity Torres, Eva; Leiva, Rosana; Gazzarrini, Sabrina; Rey-Carrizo, Matías; Frigolé-Vivas, Marta; Moroni, Anna; Naesens, Lieve; Vázquez, Santiago 2014 2014-05-05 PMC N PMC4094260 25050174.0 10.1021/ml500108s bu9e0twb 0.630217 David_2013, Largo_2016, Choudhury_2011, Abou-Hamdan_2018, Yasui_2016 Grazioso_2012, Cho_A_2012, Im_I_2009, Pérez-Faginas_2011
134 Carbone_2013 A Facile Synthesis of Deaza-Analogues of the Bisindole Marine Alkaloid Topsentin Carbone, Anna; Spanò, Virginia; Parrino, Barbara; Ciancimino, Cristina; Attanasi, Orazio A.; Favi, Gianfranco 2013 2013-02-26 COMM-USE N PMC6269752 23442928.0 10.3390/molecules18032518 sjp2c6xo 0.629394 David_2013, Choudhury_2011, Largo_2016, Abou-Hamdan_2018, Zhang_2007 Głowacka_2015, Pomeisl_2019, Głowacka_2016, Grazioso_2012
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136 Thomson_2010 Palladium-Catalyzed Aryl Amination Reactions of 6-Bromo- and 6-Chloropurine Nucleosides Thomson, Paul F.; Lagisetty, Pallavi; Balzarini, Jan; De Clercq, Erik; Lakshman, Mahesh K. 2010 2010-07-02 PMC N PMC3148652 21818182.0 10.1002/adsc.200900728 q8pmczzz 0.627198 MacDonald_2012, Yazarians_2017, Bouton_2017, Yang_2008 Pomeisl_2019, Tsoukala_2010, Głowacka_2015, Sahoo_2016
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139 Dude_2008 Synthesis and Evaluation of Non-peptidic Cysteine Protease Inhibitors of P. falciparum Derived from Etacrynic Acid Dude, Marie-Adrienne; Kaeppler, Ulrich; Herb, Monika; Schiller, Markus; Schulz, Franziska; Vedder, Birgit; Heppner, Saskia; Pradel, Gabriele; Gut, Jiri; Rosenthal, Philip J.; Schirmeister, Tanja; Leippe, Matthias; Gelhaus, Christoph 2008 2008-12-23 COMM-USE N PMC6253875 19104483.0 10.3390/molecules14010019 tsk41yjj 0.622658 Yang_2010, Naito_2007, Nisha_2014, Ramajayam_2010 Grazioso_2012, Mou_J_2009, Ramajayam_2010, Prior_2013
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142 Kim_K_2007 Design, synthesis, and biological evaluation of novel iso-d-2′,3′-dideoxy-3′-fluorothianucleoside derivatives Kim, Kyung Ran; Moon, Hyung Ryong; Park, Ah-Young; Chun, Moon Woo; Jeong, Lak Shin 2007 2007-01-01 PMC N PMC7127805 17046264.0 10.1016/j.bmc.2006.09.066 m8yfugr0 0.618482 Tallmadge_2008, Stork_2011, Ryu_W_2017, Naito_2007, Pong_2011 Singh_2010, Tsoukala_2010, Mehellou_2010
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148 Ikejiri_2007 5′-O-Masked 2′-deoxyadenosine analogues as lead compounds for hepatitis C virus (HCV) therapeutic agents Ikejiri, Masahiro; Ohshima, Takayuki; Kato, Keizo; Toyama, Masaaki; Murata, Takayuki; Shimotohno, Kunitada; Maruyama, Tokumi 2007 2007-11-15 None N PMC7125560 17766124.0 10.1016/j.bmc.2007.08.025 rt7gqiev 0.611737 Naito_2007, Berkhout_2006, Kang_2009, Volmer_2010, Liu_Y_2008 Grazioso_2012, Singh_2010
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195 Yoshida_2019 Selective and competitive inhibition of kynurenine aminotransferase 2 by glycyrrhizic acid and its analogues Yoshida, Yukihiro; Fujigaki, Hidetsugu; Kato, Koichi; Yamazaki, Kyoka; Fujigaki, Suwako; Kunisawa, Kazuo; Yamamoto, Yasuko; Mouri, Akihiro; Oda, Akifumi; Nabeshima, Toshitaka; Saito, Kuniaki 2019 2019-07-15 COMM-USE N PMC6629613 31308447.0 10.1038/s41598-019-46666-y ytto4ktu 0.566843 Blank_2017, Yang_2010, Smith_2003, Wang_2007 Kim_J_2019, Pascual_2017, Grazioso_2012, Cao_Z_2013
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227 Morán-Santibañez_2018 Virucidal and Synergistic Activity of Polyphenol-Rich Extracts of Seaweeds against Measles Virus Morán-Santibañez, Karla; Peña-Hernández, Mario A.; Cruz-Suárez, Lucia Elizabeth; Ricque-Marie, Denis; Skouta, Rachid; Vasquez, Abimael H.; Rodríguez-Padilla, Cristina; Trejo-Avila, Laura M. 2018 2018-08-30 COMM-USE N PMC6164608 30200234.0 10.3390/v10090465 4glq9iqo 0.526695 Naito_2007, Volmer_2010, Berkhout_2006, Brake_2008, Meng_2008 Liu_Z_2015, Wu_H_2016, Hsieh_2010, Lee_C_2019
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229 Balzarini_2005 Pyridine N-oxide derivatives are inhibitory to the human SARS and feline infectious peritonitis coronavirus in cell culture Balzarini, Jan; Keyaerts, Els; Vijgen, Leen; Vandermeer, Frank; Stevens, Miguel; De Clercq, Erik; Egberink, Herman; Van Ranst, Marc 2005 2005-12-29 PMC N PMC7110042 16387746.0 10.1093/jac/dki481 1ln02cyq 0.525180 Tallmadge_2008, Shen_2005, Yang_2010, Kang_2009, Clapham_1991 Hsieh_2010, Wu_H_2016, Sidhu_1996, Valle-Casuso_2020
230 Shao_2007 Structure‐Based Design and Synthesis of Highly Potent SARS‐CoV 3CL Protease Inhibitors Shao, Yi‐Ming; Yang, Wen‐Bin; Peng, Hung‐Pin; Hsu, Min‐Feng; Tsai, Keng‐Chang; Kuo, Tun‐Hsun; Wang, Andrew H.‐J.; Liang, Po‐Huang; Lin, Chun‐Hung; Yang, An‐Suei; Wong, Chi‐Huey 2007 2007-08-23 PMC N PMC7162026 17722121.0 10.1002/cbic.200700254 voem879q 0.525009 Qi_Z_2018, Choudhury_2011, Largo_2016, Abou-Hamdan_2018, David_2013
231 Zandi_2011 Antiviral activity of four types of bioflavonoid against dengue virus type-2 Zandi, Keivan; Teoh, Boon-Teong; Sam, Sing-Sin; Wong, Pooi-Fong; Mustafa, Mohd Rais; AbuBakar, Sazaly 2011 2011-12-28 COMM-USE N PMC3271998 22201648.0 10.1186/1743-422x-8-560 2vim1wno 0.522840 Tallmadge_2008, Li_C_2013, Yasui_2016, Xu_L_2014, Liu_X_2015 Ren_Z_2010, Zhou_2012, Lee_C_2019, Zhong_2009
232 Shie_2005 Inhibition of the severe acute respiratory syndrome 3CL protease by peptidomimetic α,β-unsaturated esters Shie, Jiun-Jie; Fang, Jim-Min; Kuo, Tun-Hsun; Kuo, Chih-Jung; Liang, Po-Huang; Huang, Hung-Jyun; Wu, Yin-Ta; Jan, Jia-Tsrong; Cheng, Yih-Shyun E.; Wong, Chi-Huey 2005 2005-09-01 PMC N PMC7119063 15994085.0 10.1016/j.bmc.2005.05.065 9fiqf6lk 0.522285 Ramajayam_2010, Yang_2010, Vaughan_2012, Kuang_2005, Lu_Y_1997 Grazioso_2012, Kuo_C_2008, Akaji_2008, van_der_Linden_2014
233 Xiao_2013 Concise Synthesis of Linderaspirone A and Bi‐linderone Xiao, Fenfen; Liu, Wu; Wang, Yunxia; Zhang, Qing; Li, Xiang; Hu, Xiangdong 2013 2013-01-11 None N PMC7159600 10.1002/ajoc.201200184 6t02ewpa 0.522007 Largo_2016, Abou-Hamdan_2018, David_2013, Choudhury_2011, Moon_2012
234 Liu_Q_2020 Enhancing the Antiviral Efficacy of RNA-Dependent RNA Polymerase Inhibition by Combination with Modulators of Pyrimidine Metabolism Qi Liu; Amita Gupta; Ayse Okesli-Armlovich; Wenjie Qiao; Curt R. Fischer; Mark Smith; Jan E. Carette; Michael C. Bassik; Chaitan Khosla 2020 2020-03-25 BioRxiv N 10.1101/2020.03.24.992230 1zk64gsg 0.520919 Stork_2011, Meyerson_2017, Kang_2009, Berkhout_2006, Naito_2007 Sasvari_2009, Wilde_2019, Xiong_2020
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236 Arooj_2011 3D QSAR Pharmacophore Modeling, in Silico Screening, and Density Functional Theory (DFT) Approaches for Identification of Human Chymase Inhibitors Arooj, Mahreen; Thangapandian, Sundarapandian; John, Shalini; Hwang, Swan; Park, Jong Keun; Lee, Keun Woo 2011 2011-12-12 COMM-USE N PMC3257128 22272131.0 10.3390/ijms12129236 4lmwa1yf 0.519173 Qi_Z_2018, Saw_A_2019, Liu_Z_2008, Kinjo_2012, Plewczyński_2008 Mukherjee_2011, Lee_H_2014, Thanigaimalai_2013
237 Paragas_2005 Interferon alfacon1 is an inhibitor of SARS-corona virus in cell-based models Paragas, Jason; Blatt, Lawrence M.; Hartmann, Chris; Huggins, John W.; Endy, Tim P. 2005 2005-06-30 PMC N PMC7114208 15911026.0 10.1016/j.antiviral.2005.01.002 o8ygdd14 0.518234 Ban_J_2018, Li_C_2017, Montefiori_2007, Berkhout_2006 Tan_E_2004, Spiegel_2004, Mantlo_2020
238 Krečmerová_2013 9-[2-(R)-(Phosphonomethoxy)propyl]-2,6-diaminopurine (R)-PMPDAP and its prodrugs: Optimized preparation, including identification of by-products formed, and antiviral evaluation in vitro Krečmerová, Marcela; Jansa, Petr; Dračínský, Martin; Sázelová, Petra; Kašička, Václav; Neyts, Johan; Auwerx, Joeri; Kiss, Eleonóra; Goris, Nesya; Stepan, George; Janeba, Zlatko 2013 2013-03-01 PMC N PMC7127208 23375089.0 10.1016/j.bmc.2012.12.044 enc0da59 0.517031 Naito_2007, Stork_2011, Rice_1992, Brake_2008, Kang_2009 Pomeisl_2019, Tsoukala_2010, Tabuchi_2009, Manta_2009
239 Roa-Linares_2019 Anti-Herpetic, Anti-Dengue and Antineoplastic Activities of Simple and Heterocycle-Fused Derivatives of Terpenyl-1,4-Naphthoquinone and 1,4-Anthraquinone † Roa-Linares, Vicky C.; Miranda-Brand, Yaneth; Tangarife-Castaño, Verónica; Ochoa, Rodrigo; García, Pablo A.; Castro, Mª Ángeles; Betancur-Galvis, Liliana; San Feliciano, Arturo 2019 2019-04-02 COMM-USE N PMC6479402 30986933.0 10.3390/molecules24071279 oaehj3n8 0.516036 Naito_2007, Li_C_2013, Kang_2009, Volmer_2010, Ban_J_2018 Roa-Linares_2016, Ren_Z_2010, Grazioso_2012, Zhao_2016
240 Quintiliani_2011 Design, synthesis and biological evaluation of 2′-deoxy-2′,2′-difluoro-5-halouridine phosphoramidate ProTides Quintiliani, Maurizio; Persoons, Leentje; Solaroli, Nicola; Karlsson, Anna; Andrei, Graciela; Snoeck, Robert; Balzarini, Jan; McGuigan, Christopher 2011 2011-07-15 PMC N PMC7127735 21696963.0 10.1016/j.bmc.2011.05.037 hkwlsn03 0.514856 Kumar_2016, Meyerson_2017, Tallmadge_2008, Ban_J_2018, Li_C_2017 Cho_A_2012, Li_W_2008, Tsoukala_2010
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242 Abou-Elkhair_2014 Synthesis and biological evaluation of 2-oxonicotinonitriles and 2-oxonicotinonitrile based nucleoside analogues Abou-Elkhair, Reham A.I.; Moustafa, Ahmed H.; Haikal, Abdelfattah Z.; Ibraheem, Ahmed M. 2014 2014-03-03 None N PMC7115408 24486419.0 10.1016/j.ejmech.2013.12.055 u87h2bbp 0.512799 Naito_2007, Berkhout_2006, Callison_1999, Bahir_2009, Volmer_2010 Grazioso_2012, Carbone_2013, Sahoo_2016, Pomeisl_2019
243 Šála_2016 Purine analogs as phosphatidylinositol 4-kinase IIIβ inhibitors Šála, Michal; Kögler, Martin; Plačková, Pavla; Mejdrová, Ivana; Hřebabecký, Hubert; Procházková, Eliška; Strunin, Dmytro; Lee, Gary; Birkus, Gabriel; Weber, Jan; Mertlíková-Kaiserová, Helena; Nencka, Radim 2016 2016-06-01 PMC N PMC7127540 27090557.0 10.1016/j.bmcl.2016.04.002 kifnohj9 0.512494 Qi_Z_2018, Chang_2011, Wu_G_2005, Ivarsson_2012, Polverino_2017 Grazioso_2012, Im_I_2009, Pérez-Faginas_2011
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245 Serrano-Heranz_2010 Infecciones por neumococo. Clasificación. Factores predisponentes. Aspectos patogénicos de relevancia clínica o diagnóstica. Manifestaciones clínicas. Formas de comienzo Serrano-Heranz, R.; Sicilia-Urbán, J.J.; Sanz-Rojas, P. 2010 2010-03-31 PMC N PMC7143697 10.1016/s0304-5412(10)70042-1 f07rc8ig 0.512377 Isea_de_la_Viña_2020, Pedersen_1992, Calvo_2020, UNKNOWN_2012
246 Hjortland_2016 Steady-state kinetic studies reveal that the anti-cancer target Ubiquitin-Specific Protease 17 (USP17) is a highly efficient deubiquitinating enzyme Hjortland, Nicole M.; Mesecar, Andrew D. 2016 2016-12-01 PMC N PMC5868344 27756680.0 10.1016/j.abb.2016.10.008 nwl5i9h6 0.512377 Banik_2016, Alqahtani_2016, Gogineni_2015, Mao_H_2019 UNKNOWN_2015
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248 Lim_J_2020 The Author's Response: Case of the Index Patient Who Caused Tertiary Transmission of Coronavirus Disease 2019 in Korea: the Application of Lopinavir/Ritonavir for the Treatment of COVID-19 Pneumonia Monitored by Quantitative RT-PCR Lim, Jaegyun; Jeon, Seunghyun; Shin, Hyun Young; Kim, Moon Jung; Seong, Yu Min; Lee, Wang Jun; Choe, Kang Won; Kang, Yu Min; Lee, Baeckseung; Park, Sang Joon 2020 2020-01-01 NONCOMM N 32080993.0 10.3346/jkms.2020.35.e89 fjmchbew 0.512377 Moon_2017
249 Khanna_2020 Spiro‐Indole‐Coumarin Hybrids: Synthesis, ADME, DFT, NBO Studies and In Silico Screening through Molecular Docking on DNA G‐Quadruplex Khanna, Leena; Singhal, Sugandha; Jain, Subhash C.; Khanna, Pankaj 2020 2020-03-19 PMC N PMC7169502 10.1002/slct.201904783 5drr3fyt 0.509996 Kinjo_2012, Jiang_2011, Dai_Q_2012, Chang_2011, Liao_2006
250 Wang_2012 First Discovery and Stucture-Activity Relationship Study of Phenanthroquinolizidines as Novel Antiviral Agents against Tobacco Mosaic Virus (TMV) Wang, Ziwen; Feng, Anzheng; Cui, Mingbo; Liu, Yuxiu; Wang, Lizhong; Wang, Qingmin 2012 2012-12-28 COMM-USE N PMC3532156 23285230.0 10.1371/journal.pone.0052933 5is9kc52 0.505780 Berkhout_2006, Naito_2007, Volmer_2010, Kang_2009, Stork_2011 Ren_Z_2010, Nie_L_2020, Zhao_2016, Chathuranga_2019
251 Kuo_R_2009 Plant-derived triterpenoids and analogues as antitumor and anti-HIV agents Kuo, Reen-Yen; Qian, Keduo; Morris-Natschke, Susan L.; Lee, Kuo-Hsiung 2009 2009-01-01 PMC N PMC3773821 19779642.0 10.1039/b810774m 035o1pen 0.501742 Xu_X_2016, SU_Y_2016, WU_L_2015, Sun_Y_2016 Ramajayam_2010, Dude_2008, Yadav_2005
252 Ukrainets_2008 4-Hydroxy-2-quinolones 139. Synthesis, structure, and antiviral activity of N-R-amides of 2-hydroxy-4-oxo-4H-pyrido[1,2-a]pyrimidine-3-carboxylic acids Ukrainets, I. V.; Bereznyakova, N. L.; Turaibei, I. A. 2008 2008-05-31 PMC N PMC7088292 10.1007/s10593-008-0012-x qe5w17iz 0.501626 Rice_1992, Naito_2007, Berkhout_2006, den_Boon_2010, Karlsson_2012 Grazioso_2012, Paramonova_2017, Głowacka_2015, Kumarapperuma_2007
253 Konno_2017 Synthesis and evaluation of phenylisoserine derivatives for the SARS-CoV 3CL protease inhibitor Konno, Hiroyuki; Onuma, Takumi; Nitanai, Ikumi; Wakabayashi, Masaki; Yano, Shigekazu; Teruya, Kenta; Akaji, Kenichi 2017 2017-06-15 PMC N PMC7127027 28454669.0 10.1016/j.bmcl.2017.04.056 qym6jch0 0.501283 Tallmadge_2008, Pong_2011, Ramajayam_2010, Naito_2007 Ramajayam_2010, Konno_2016, Dude_2008, Konno_2013
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256 Hsu_J_2004 Evaluation of metal-conjugated compounds as inhibitors of 3CL protease of SARS-CoV Hsu, John T.-A.; Kuo, Chih-Jung; Hsieh, Hsing-Pang; Wang, Yeau-Ching; Huang, Kuo-Kuei; Lin, Coney P.-C.; Huang, Ping-Fang; Chen, Xin; Liang, Po-Huang 2004 2004-09-10 PMC N PMC7134601 15358550.0 10.1016/j.febslet.2004.08.015 8sc6nbqp 0.500487 Ramajayam_2010, Yang_2010, Saura_1999, Kang_2009, Meyerson_2017 Grazioso_2012, Liu_W_2014, van_der_Linden_2014, Su_H_2020
257 Ye_N_2015 Structure–Activity Relationship Studies of Substituted 2-(Isoxazol-3-yl)-2-oxo-N′-phenyl-acetohydrazonoyl Cyanide Analogues: Identification of Potent Exchange Proteins Directly Activated by cAMP (EPAC) Antagonists Ye, Na; Zhu, Yingmin; Chen, Haijun; Liu, Zhiqing; Mei, Fang C.; Wild, Christopher; Chen, Haiying; Cheng, Xiaodong; Zhou, Jia 2015 2015-07-16 PMC N PMC4769034 26151319.0 10.1021/acs.jmedchem.5b00635 3yk35rr0 0.500487 Ivarsson_2012, Leung_2012, Berkhout_2006, Haasnoot_2010, Postigo_2009 Grazioso_2012, Deiab_2015
258 Tian_2012 Discovery of novel low-molecular-weight HIV-1 inhibitors interacting with cyclophilin A using in silico screening and biological evaluations Tian, Yu-Shi; Verathamjamras, Chris; Kawashita, Norihito; Okamoto, Kousuke; Yasunaga, Teruo; Ikuta, Kazuyoshi; Kameoka, Masanori; Takagi, Tatsuya 2012 2012-09-05 PMC N PMC7088282 22949064.0 10.1007/s00894-012-1560-7 yq9ol5qa 0.494686 Naito_2007, Berkhout_2006, Liu_Y_2008, Rice_1992, Haasnoot_2010 Zhu_X_2015, Lee_C_2019, Li_J_2006
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260 Rauvolfova_2008 Chemo-enzymatic synthesis of C-9 acetylated sialosides Rauvolfova, Jana; Venot, Andre; Boons, Geert-Jan 2008 2008-07-21 PMC N 18508039.0 10.1016/j.carres.2008.05.002 24um8t1y 0.493637 David_2013, Largo_2016, Choudhury_2011, Abou-Hamdan_2018, Schmidt_1982 Głowacka_2015, Tsoukala_2010, Pomeisl_2019, Liu_M_2018
261 Kaminskyy_2017 5-Ene-4-thiazolidinones – An efficient tool in medicinal chemistry Kaminskyy, Danylo; Kryshchyshyn, Anna; Lesyk, Roman 2017 2017-11-10 PMC N PMC7111298 28987611.0 10.1016/j.ejmech.2017.09.031 nzykgiyr 0.493297 Liu_Z_2008, Chang_2011, Dai_Q_2012, Staple_2005, Naito_2007 Carbone_2013, Bozorov_2019, Kryshchyshyn_2018, Sahoo_2016
262 Pahonțu_2015 Synthesis, Characterization, Crystal Structure and Antimicrobial Activity of Copper(II) Complexes with the Schiff Base Derived from 2-Hydroxy-4-Methoxybenzaldehyde Pahonțu, Elena; Ilieș, Diana-Carolina; Shova, Sergiu; Paraschivescu, Codruța; Badea, Mihaela; Gulea, Aurelian; Roșu, Tudor 2015 2015-04-02 COMM-USE N PMC6272500 25849802.0 10.3390/molecules20045771 0wcvoygd 0.492678 David_2013, Choudhury_2011, Largo_2016, Abou-Hamdan_2018 Yang_2010, Sahoo_2016, Zhang_2017, Tabuchi_2009
263 Liu_M_2018 The enzymatic biosynthesis of acylated steroidal glycosides and their cytotoxic activity Liu, Ming; Kong, Jian-Qiang 2018 2018-05-01 NONCOMM N PMC6251810 30505666.0 10.1016/j.apsb.2018.04.006 abs9rvjk 0.492446 Wang_2007, Stork_2011, Berkhout_2006, UNKNOWN_1996, Blank_2017 Yuan_2018, Rauvolfova_2008, Xie_J_2018
264 Šafář_2016 Use of chiral-pool approach into epi-thieno analogues of the scarce bioactive phenanthroquinolizidine alkaloids Šafář, Peter; Marchalín, Štefan; Prónayová, Nadežda; Vrábel, Viktor; Lawson, Ata Martin; Othman, Mohamed; Daïch, Adam 2016 2016-06-09 None N PMC7111795 10.1016/j.tet.2016.04.047 3po8e5s7 0.492341 MacDonald_2012, Yazarians_2017, Bouton_2017, Mlostoń_2010 Pomeisl_2019, Grazioso_2012, Carbone_2013, Tsoukala_2010
265 Fang_2013 Identification of Three Antiviral Inhibitors against Japanese Encephalitis Virus from Library of Pharmacologically Active Compounds 1280 Fang, Jin'e; Sun, Leqiang; Peng, Guiqing; Xu, Jia; Zhou, Rui; Cao, Shengbo; Chen, Huanchun; Song, Yunfeng 2013 2013-11-04 COMM-USE N PMC3857149 24348901.0 10.1371/journal.pone.0078425 xkqxawj2 0.490480 Tallmadge_2008, Naito_2007, Ishag_2012, Li_C_2013, Yasui_2016 Hu_H_2019, Lee_C_2019, Zhou_2012, Ishag_2012
266 Shao_2008 Design, synthesis, and evaluation of trifluoromethyl ketones as inhibitors of SARS-CoV 3CL protease Shao, Yi-Ming; Yang, Wen-Bin; Kuo, Tun-Hsun; Tsai, Keng-Chang; Lin, Chun-Hung; Yang, An-Suei; Liang, Po-Huang; Wong, Chi-Huey 2008 2008-04-15 PMC N PMC7127754 18329272.0 10.1016/j.bmc.2008.02.040 pgzogpa2 0.490383 Ramajayam_2010, Yang_2010, Regnier_2009, Wu_G_2005 Pérez-Faginas_2011, Ramajayam_2010, Prior_2013, Konno_2016
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270 Paasche_2010 Mechanistic Study of the Reaction of Thiol‐Containing Enzymes with α,β‐Unsaturated Carbonyl Substrates by Computation and Chemoassays Paasche, Alexander; Schiller, Markus; Schirmeister, Tanja; Engels, Bernd 2010 2010-04-16 None N PMC7162195 20401893.0 10.1002/cmdc.201000020 nohulpkn 0.487797 Ivarsson_2012, Smith_2003, Chan_2016, Wu_G_2005, Zhao_2017
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272 Deiab_2015 1,2,3,4,6-Penta-O-galloylglucose within Galla Chinensis Inhibits Human LDH-A and Attenuates Cell Proliferation in MDA-MB-231 Breast Cancer Cells Deiab, Shihab; Mazzio, Elizabeth; Eyunni, Suresh; McTier, Oshlii; Mateeva, Nelly; Elshami, Faisel; Soliman, Karam F. A. 2015 2015-03-30 COMM-USE N PMC4396556 25918543.0 10.1155/2015/276946 6rs7koqx 0.487156 Bie_C_2016, Zhang_2007, Yang_2010, Volmer_2010, Blank_2017 Grazioso_2012, Deiab_2013, Xie_J_2018, Mehellou_2010
273 Kim_J_2019 Anti-cariogenic Characteristics of Rubusoside Kim, Jeesoo; Nguyen, Thi Thanh Hanh; Jin, Juhui; Septiana, Iis; Son, Gyu-Min; Lee, Gang-Hee; Jung, You-Jin; Qureshi, Dilshad; Mok, Il Kyoon; Pal, Kunal; Yang, Soo-Yeon; Kim, Seong-Bo; Kim, Doman 2019 2019-05-18 PMC N PMC7090897 10.1007/s12257-018-0408-0 xswtuaeq 0.486055 David_2013, Abou-Hamdan_2018, Largo_2016, Choudhury_2011 Klein_2008, Taherkhani_2013, Park_2017, Ren_Z_2010
274 Kumar_2013 Synthesis, antitubercular and anticancer activity of new Baylis–Hillman adduct-derived N-cinnamyl-substituted isatin derivatives Kumar, Sriramoju Bharath; Ravinder, Mettu; Kishore, Golla; Jayathirtha Rao, Vaidya; Yogeeswari, Perumal; Sriram, Darmarajan 2013 2013-09-26 PMC N PMC7080103 10.1007/s00044-013-0787-x vwthwjlm 0.485571 Zhang_2007, Oosterhoff_2015, Ishii_1992, Schat_1987 Grazioso_2012, Ren_Z_2010, Lee_C_2020, Cao_Z_2013
275 Sun_Y_2013 Synthesis and Biological Evaluation of Quinolinone Compounds as SARS CoV 3CL(pro) Inhibitors Sun, Yuanpei; Zhang, Ning; Wang, Jian; Guo, Yu; Sun, Bo; Liu, Wei; Zhou, Honggang; Yang, Cheng 2013 2013-07-19 PMC N PMC7159103 10.1002/cjoc.201300392 ew6kqsfr 0.484639 Naito_2007, Zhang_2004, Ban_J_2018, Ramajayam_2010, Berkhout_2006
276 Shah_2010 A Small-Molecule Oxocarbazate Inhibitor of Human Cathepsin L Blocks Severe Acute Respiratory Syndrome and Ebola Pseudotype Virus Infection into Human Embryonic Kidney 293T cells Shah, Parag P.; Wang, Tianhua; Kaletsky, Rachel L.; Myers, Michael C.; Purvis, Jeremy E.; Jing, Huiyan; Huryn, Donna M.; Greenbaum, Doron C.; Smith, Amos B.; Bates, Paul; Diamond, Scott L. 2010 2010-05-13 PMC N PMC2917856 20466822.0 10.1124/mol.110.064261 3e27bu82 0.483954 Pager_2006, Tallmadge_2008, Yang_2010, Liu_X_2015, Meng_2014 Grazioso_2012, Opsenica_2011, Zhong_2009, Zhu_X_2015
277 Konno_2013 Design and synthesis of new tripeptide-type SARS-CoV 3CL protease inhibitors containing an electrophilic arylketone moiety Konno, Sho; Thanigaimalai, Pillaiyar; Yamamoto, Takehito; Nakada, Kiyohiko; Kakiuchi, Rie; Takayama, Kentaro; Yamazaki, Yuri; Yakushiji, Fumika; Akaji, Kenichi; Kiso, Yoshiaki; Kawasaki, Yuko; Chen, Shen-En; Freire, Ernesto; Hayashi, Yoshio 2013 2013-01-15 PMC N PMC7127713 23245752.0 10.1016/j.bmc.2012.11.017 esogd26s 0.482873 Ivarsson_2012, Naito_2007, Smith_2003, Perrone_2015, Chan_2016 Thanigaimalai_2013, Thanigaimalai_2013, Niu_C_2008, Grazioso_2012
278 Pervez_2011 Synthesis and Toxicity Evaluation of Some N(4)-Aryl Substituted 5-Trifluoromethoxyisatin-3-thiosemicarbazones Pervez, Humayun; Saira, Naveeda; Iqbal, Mohammad Saeed; Yaqub, Muhammad; Khan, Khalid Mohammed 2011 2011-07-29 COMM-USE N PMC6264754 25134761.0 10.3390/molecules16086408 a7hiw0vw 0.482567 Abou-Hamdan_2018, Choudhury_2011, Largo_2016, David_2013, Callison_1999 Pomeisl_2019, Głowacka_2015, Głowacka_2016, Carbone_2013
279 Gondim_2019 Potent antiviral activity of carbohydrate-specific algal and leguminous lectins from the Brazilian biodiversity Gondim, Ana C. S.; Roberta da Silva, Suzete; Mathys, Leen; Noppen, Sam; Liekens, Sandra; Holanda Sampaio, Alexandre; Nagano, Celso S.; Renata Costa Rocha, Cintia; Nascimento, Kyria S.; Cavada, Benildo S.; Sadler, Peter J.; Balzarini, Jan 2019 2019-01-14 COMM-USE N PMC6430086 30996857.0 10.1039/c8md00508g jbain7n6 0.482213 Ryu_W_2017, Yasui_2016, Wang_2015, Rice_1992, Tallmadge_2008 Lee_C_2019, Xie_J_2018, Ren_Z_2010, Tabares_2011
280 Tayade_2015 An efficient synthesis of 3-indolyl-3-hydroxy oxindoles and 3,3-di(indolyl)indolin-2-ones catalyzed by sulfonated β-CD as a supramolecular catalyst in water Tayade, Yogesh A.; Patil, Dipak R.; Wagh, Yogesh B.; Jangle, Asha D.; Dalal, Dipak S. 2015 2015-01-28 PMC N PMC7111843 10.1016/j.tetlet.2014.12.012 ac08um4i 0.481896 MacDonald_2012, Yazarians_2017, Kale_2010, Tarui_2010 Paramonova_2017, Riahi_2009, Ahadi_2011, Chopade_2016
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282 Roman_2015 Mannich bases in medicinal chemistry and drug design Roman, Gheorghe 2015 2015-01-07 PMC N PMC7115492 25462280.0 10.1016/j.ejmech.2014.10.076 f8pyn3rx 0.477496 Zakaryan_2017, Gul_W_2005, Ancheeva_2018, Pastuch-Gawołek_2019 Cao_Z_2013, Xuan_2016, Medvedev_2007, Grazioso_2012
283 Lin_P_2008 A novel and exploitable antifungal peptide from kale (Brassica alboglabra) seeds Lin, Peng; Ng, Tzi Bun 2008 2008-10-31 PMC N PMC7115674 18597893.0 10.1016/j.peptides.2008.05.020 hj9s5cnu 0.477076 Wu_X_2011, Lin_P_2009, Hong_2013, Welling_1987 Xie_J_2018, Gondim_2019, Cheng_2014
284 Lin_Z_2012 Facile cleavage of C–C bond: conversion of pyrane derivative to 1,3-oxazin derivative Lin, Zhilan; Zhang, Xueli; You, Xinkui; Gao, Yuan 2012 2012-08-19 PMC N PMC7111841 10.1016/j.tet.2012.05.089 kpkyit07 0.476159 Kale_2010, MacDonald_2012, Yazarians_2017, Zhao_2017 Sobenina_2018, Kale_2010, Paramonova_2017, Tayade_2015
285 Attia_2017 New hydrazonoindolin-2-ones: Synthesis, exploration of the possible anti-proliferative mechanism of action and encapsulation into PLGA microspheres Attia, Mohamed I.; Eldehna, Wagdy M.; Afifi, Samar A.; Keeton, Adam B.; Piazza, Gary A.; Abdel-Aziz, Hatem A. 2017 2017-07-25 COMM-USE N PMC5526551 28742842.0 10.1371/journal.pone.0181241 sq5iod1w 0.475896 Zhang_2007, Bie_C_2016, Brake_2008, Kubo_2012, González-González_2008 Grazioso_2012, Carbone_2013, Zhang_2018, Sahoo_2016
286 Theerawatanasirikul_2020 In silico and in vitro analysis of small molecules and natural compounds targeting the 3CL protease of feline infectious peritonitis virus Theerawatanasirikul, Sirin; Kuo, Chih Jung; Phetcharat, Nanthawan; Lekcharoensuk, Porntippa 2020 2020-02-29 PMC N PMC7114316 31863793.0 10.1016/j.antiviral.2019.104697 upzmzauj 0.475853 Naito_2007, Berkhout_2006, Rice_1992, Kang_2009, Liu_Y_2008 van_der_Linden_2014, Lee_C_2019, Tian_2012, Lee_H_2019
287 Nguyen_2012 Flavonoid-mediated inhibition of SARS coronavirus 3C-like protease expressed in Pichia pastoris Nguyen, Thi Thanh Hanh; Woo, Hye-Jin; Kang, Hee-Kyoung; Nguyen, Van Dao; Kim, Young-Min; Kim, Do-Won; Ahn, Sul-Ah; Xia, Yongmei; Kim, Doman 2012 2012-02-15 PMC N PMC7087583 22350287.0 10.1007/s10529-011-0845-8 37ricask 0.474974 Choudhury_2011, David_2013, Abou-Hamdan_2018, Largo_2016, Yang_2010 Chen_2005, van_der_Linden_2014, Lee_C_2009, Zhu_L_2011
288 Naesens_2009 Anti-influenza virus activity and structure–activity relationship of aglycoristocetin derivatives with cyclobutenedione carrying hydrophobic chains Naesens, Lieve; Vanderlinden, Evelien; Rőth, Erzsébet; Jekő, József; Andrei, Graciela; Snoeck, Robert; Pannecouque, Christophe; Illyés, Eszter; Batta, Gyula; Herczegh, Pál; Sztaricskai, Ferenc 2009 2009-04-30 PMC N PMC7125606 19200809.0 10.1016/j.antiviral.2009.01.003 0sw3wt1i 0.474710 Yasui_2016, Tallmadge_2008, Lu_P_2016, Naito_2007, Volmer_2010 Szűcs_2018, Lee_C_2019, Lin_J_2008, Zhu_X_2015
289 Novikov_2013 Synthesis and anti-HCMV activity of 1-[ω-(phenoxy)alkyl]uracil derivatives and analogues thereof Novikov, Mikhail S.; Babkov, Denis A.; Paramonova, Maria P.; Khandazhinskaya, Anastasia L.; Ozerov, Alexander A.; Chizhov, Alexander O.; Andrei, Graciela; Snoeck, Robert; Balzarini, Jan; Seley-Radtke, Katherine L. 2013 2013-07-15 PMC N PMC7127185 23743443.0 10.1016/j.bmc.2013.05.009 vxr15lvy 0.474507 Naito_2007, Berkhout_2006, Volmer_2010, Haasnoot_2010, Trobaugh_2017 Grazioso_2012, Pérez-Faginas_2011, Wang_2014, Zhu_X_2015
290 Nematollahi_2017 A green strategy for the synthesis of sulfone derivatives of p-methylaminophenol: Kinetic evaluation and antibacterial susceptibility Nematollahi, Davood; Khazalpour, Sadegh; Ranjbar, Mina; Momeni, Shima 2017 2017-06-30 COMM-USE N PMC5493611 28667267.0 10.1038/s41598-017-04581-0 yygb25wm 0.474095 Abou-Hamdan_2018, David_2013, Largo_2016, Choudhury_2011, Siebert_2018 Sahoo_2016, Grazioso_2012, Carbone_2013, Pomeisl_2019
291 Kashman_1987 Reiswigins A and B, novel antiviral diterpenes from a deepwater sponge Kashman, Y.; Hirsch, S.; Koehn, F.; Cross, S. 1987 1987-12-31 PMC N 10.1016/s0040-4039(00)96754-6 mfipcln2 0.473343 David_2013, Largo_2016, Choudhury_2011, Abou-Hamdan_2018 Dude_2008, Kasthuri_2011, Lin_Z_2012
292 Yang_2019 Design and Synthesis of Novel Anti-Proliferative Emodin Derivatives and Studies on their Cell Cycle Arrest, Apoptosis Pathway and Migration Yang, Kun; Jin, Ming-Ji; Quan, Zhe-Shan; Piao, Hu-Ri 2019 2019-03-02 COMM-USE N PMC6429262 30832378.0 10.3390/molecules24050884 tazd6dvm 0.473289 Bie_C_2016, Zhang_2007, Berkhout_2006, Chen_2002 Zhang_2018, Park_2017, Ren_Z_2010, Li_L_2012
293 Ma-Lauer_2020 Influences of cyclosporin A and non-immunosuppressive derivatives on cellular cyclophilins and viral nucleocapsid protein during human coronavirus 229E replication Ma-Lauer, Yue; Zheng, Yu; Malešević, Miroslav; von Brunn, Brigitte; Fischer, Gunter; von Brunn, Albrecht 2020 2020-01-31 PMC N PMC7114175 31634494.0 10.1016/j.antiviral.2019.104620 ptihe6fu 0.473153 Meyerson_2017, Ban_J_2018, Compton_2014, Kang_2009, Liu_X_2013 Wilde_2019, Tanaka_2013
294 Gong_2019 Antiviral effect of amiloride on replication of foot and mouth disease virus in cell culture Gong, Mei-jiao; Chang, Yan-yan; Shao, Jun–jun; Li, Shi-fang; Zhang, Yong-guang; Chang, Hui-yun 2019 2019-10-31 PMC N PMC7125800 31326561.0 10.1016/j.micpath.2019.103638 eveoz2ho 0.472096 Tallmadge_2008, Yasui_2016, Lu_P_2016, Compton_2014 Zhong_2009, Wu_H_2016, Sidhu_1996, Hsieh_2010
295 Vliegen_2009 Substituted imidazopyridines as potent inhibitors of HCV replication Vliegen, Inge; Paeshuyse, Jan; De Burghgraeve, Tine; Lehman, Laura S.; Paulson, Matthew; Shih, I-Hung; Mabery, Eric; Boddeker, Nina; De Clercq, Erik; Reiser, Hans; Oare, David; Lee, William A.; Zhong, Weidong; Bondy, Steven; Pürstinger, Gerhard; Neyts, Johan 2009 2009-05-31 PMC N PMC7114863 19303654.0 10.1016/j.jhep.2008.12.028 j09mf1ad 0.471353 Tallmadge_2008, Kang_2009, Rice_1992, Meyerson_2017, Liu_H_2009 Obeid_2011, Tonelli_2017, Ergonul_2007
296 Varró_2018 Stereoselective synthesis of trans-dihydronarciclasine derivatives containing a 1,4-benzodioxane moiety Varró, Gábor; Pogrányi, Balázs; Grün, Alajos; Simon, András; Hegedűs, László; Kádas, István 2018 2018-10-26 PMC N PMC7087796 10.1007/s00706-018-2287-7 j225gjx1 0.470403 Choudhury_2011, Abou-Hamdan_2018, David_2013, Largo_2016, Liu_L_2016 Pomeisl_2019, Tsoukala_2010, Carbone_2013, Głowacka_2015
297 Rey-Carrizo_2013 3-Azatetracyclo[5.2.1.1(5,8).0(1,5)]undecane derivatives: from wild-type inhibitors of the M2 ion channel of influenza A virus to derivatives with potent activity against the V27A mutant Rey-Carrizo, Matias; Torres, Eva; Ma, Chunlong; Barniol-Xicota, Marta; Wang, Jun; Wu, Yibing; Naesens, Lieve; DeGrado, William F.; Lamb, Robert A.; Pinto, Lawrence H.; Vázquez, Santiago 2013 2013-11-15 PMC N PMC3889466 24237039.0 10.1021/jm401340p t4nk2l0z 0.468943 Yang_2010, Volmer_2010, Wang_2012, Shen_2005 Pomeisl_2019, Grazioso_2012, Głowacka_2015, Piotrowska_2012
298 Xu_B_2012 12 Advances in Cancer Chemotherapeutic Drug Research in China Xu, Bin; Ding, Jian; Chen, Kai-Xian; Miao, Ze-Hong; Huang, He; Liu, Hong; Luo, Xiao-Min 2012 2012-12-31 PMC N PMC7158183 10.1016/b978-0-12-397833-2.00012-1 dcll52nd 0.467182 Pastuch-Gawołek_2019, Xu_X_2016, Zakaryan_2017, Liu_A_2012, Kuo_R_2009 Chen_2019, Zhang_2018, Hsu_S_2012
299 Babkov_2015 Toward the discovery of dual HCMV–VZV inhibitors: Synthesis, structure activity relationship analysis, and cytotoxicity studies of long chained 2-uracil-3-yl-N-(4-phenoxyphenyl)acetamides Babkov, Denis A.; Khandazhinskaya, Anastasia L.; Chizhov, Alexander O.; Andrei, Graciela; Snoeck, Robert; Seley-Radtke, Katherine L.; Novikov, Mikhail S. 2015 2015-11-01 PMC N PMC7126728 26443550.0 10.1016/j.bmc.2015.09.033 6g7jz7ma 0.466388 Tallmadge_2008, Lu_P_2016, Potgieter_1986, Ryu_W_2017, De_Clercq_2005 Grazioso_2012, Musella_2016, Opsenica_2011
300 Li_J_2013 Epimeric methylsulfinyladenosine derivatives from the marine ascidian Herdmania momus Li, Jian Lin; Kim, Eun La; Wang, Haibo; Hong, Jongki; Shin, Sook; Lee, Chong-Kyo; Jung, Jee H. 2013 2013-08-15 PMC N PMC7127152 23810281.0 10.1016/j.bmcl.2013.05.097 o23wv5jw 0.466194 Kuo_R_2009, Rice_1992, Wang_2018, Naito_2007 Dude_2008, Xie_J_2018, Almeida_2011, Grazioso_2012
301 Lin_J_2008 Inhibitory effects of some derivatives of glycyrrhizic acid against Epstein-Barr virus infection: Structure–activity relationships Lin, Jung-Chung; Cherng, Jaw-Ming; Hung, Man-Shan; Baltina, Lidia A.; Baltina, Lia; Kondratenko, Rimma 2008 2008-07-31 PMC N PMC7114209 18423902.0 10.1016/j.antiviral.2008.01.160 jzmwy4yi 0.465700 Yang_2010, Kang_2009, Meng_2008, Meyerson_2017, Ban_J_2018 Zhou_2012, Lee_C_2019, Ren_Z_2010, Sabouri_Ghannad_2014
302 Martínez-Gualda_2019 Modifications in the branched arms of a class of dual inhibitors of HIV and EV71 replication expand their antiviral spectrum Martínez-Gualda, Belén; Sun, Liang; Martí-Marí, Olaia; Mirabelli, Carmen; Delang, Leen; Neyts, Johan; Schols, Dominique; Camarasa, María-José; San-Félix, Ana 2019 2019-08-31 PMC N PMC7114229 31228490.0 10.1016/j.antiviral.2019.06.006 8gbk3mt9 0.461319 Naito_2007, Tallmadge_2008, Rice_1992, Volmer_2010, den_Boon_2010 Zhu_X_2015, Lee_C_2019, Yates_2019, Kuo_C_2008
303 Baltina_2019 Glycyrrhizic acid derivatives as Dengue virus inhibitors Baltina, Lidia A.; Tasi, Yan-Ting; Huang, Su-Hua; Lai, Hsueh-Chou; Baltina, Lia A.; Petrova, Svetlana F.; Yunusov, Marat S.; Lin, Cheng-Wen 2019 2019-10-15 PMC N 31519375.0 10.1016/j.bmcl.2019.126645 uip911q3 0.461235 Tallmadge_2008, Yasui_2016, Compton_2014, Yang_2010, Clapham_1991
304 Karypidou_2018 Synthesis, biological evaluation and molecular modeling of a novel series of fused 1,2,3-triazoles as potential anti-coronavirus agents Karypidou, Konstantina; Ribone, Sergio R.; Quevedo, Mario A.; Persoons, Leentje; Pannecouque, Christophe; Helsen, Christine; Claessens, Frank; Dehaen, Wim 2018 2018-11-15 None N PMC7127349 30286952.0 10.1016/j.bmcl.2018.09.019 qslepo4b 0.459769 Naito_2007, Rice_1992, Berkhout_2006, Stork_2011 Grazioso_2012, Hamada_2013, Konno_2013, Kumarasamy_2017
305 Hariono_2019 Thioguanine-based DENV-2 NS2B/NS3 protease inhibitors: Virtual screening, synthesis, biological evaluation and molecular modelling Hariono, Maywan; Choi, Sy Bing; Roslim, Ros Fatihah; Nawi, Mohamed Sufian; Tan, Mei Lan; Kamarulzaman, Ezatul Ezleen; Mohamed, Nornisah; Yusof, Rohana; Othman, Shatrah; Abd Rahman, Noorsaadah; Othman, Rozana; Wahab, Habibah A. 2019 2019-01-24 None N PMC6345492 30677071.0 10.1371/journal.pone.0210869 46r0ne4f 0.459392 Naito_2007, Callison_1999, Volmer_2010, Chan_2016, Kang_2009 Kaczor_2010, Zhu_X_2015, Grazioso_2012
306 Lammers_2010 Acetylation regulates Cyclophilin A catalysis, immunosuppression and HIV isomerisation Lammers, Michael; Neumann, Heinz; Chin, Jason W.; James, Leo C. 2010 2010-04-04 None N PMC3867001 20364129.0 10.1038/nchembio.342 oc1syzur 0.459136 Meyerson_2017, Ban_J_2018, Blank_2017, Greene_2012, Yasuda-Inoue_2013 Zhou_2012, de_Wilde_2018, Peel_2013, Deng_2019
307 Overacker_2019 Biological Evaluation of Molecules of the azaBINOL Class as Antiviral Agents: Specific Inhibition of HIV-1 RNase H Activity by 7-Isopropoxy-8-(naphth-1-yl)quinoline Ross D. Overacker; Somdev Banerjee; George F. Neuhaus; Selena Milicevic Sephton; Alexander Herrmann; James A. Strother; Ruth Brack-Werner; Paul R. Blakemore; Sandra Loesgen 2019 2019-01-23 BioRxiv N 10.1101/525105 m2zw8eq4 0.458651 Naito_2007, Stork_2011, Rice_1992, Berkhout_2006, Kang_2009 Grazioso_2012, Opsenica_2011, Zhao_2016, Hamada_2013
308 Li_S_2005 Identification of natural compounds with antiviral activities against SARS-associated coronavirus Li, Shi-you; Chen, Cong; Zhang, Hai-qing; Guo, Hai-yan; Wang, Hui; Wang, Lin; Zhang, Xiang; Hua, Shi-neng; Yu, Jun; Xiao, Pei-gen; Li, Rong-song; Tan, Xuehai 2005 2005-07-31 PMC N PMC7114104 15885816.0 10.1016/j.antiviral.2005.02.007 4s57ls6y 0.457934 Naito_2007, Tallmadge_2008, Volmer_2010, Liu_Y_2008, Ishag_2016 Ren_Z_2010, Jo_S_2019, Su_H_2020, Chen_2005
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311 Karpińska_2013 On constitutional isomers and tautomers of oxadiazolones and their mono- and disulfur analogues (C2H2N2XY; X,Y=S,O) Karpińska, Grażyna; Dobrowolski, Jan Cz. 2013 2013-02-01 PMC N PMC7104208 10.1016/j.comptc.2012.11.003 ehqerbt1 0.453564 Langosch_2011, Kierzek_2006, Apgar_2008, Deng_2006 Pomeisl_2019, Piotrowska_2019, Yoshizawa_2020, Szűcs_2018
312 Cozza_2018 Hydrophobic Derivatives of Glycopeptide Antibiotics as Inhibitors of Protein Kinases Cozza, G.; Fortuna, M.; Meggio, F.; Sarno, S.; Kubbutat, M. H. G.; Totzke, F.; Schaechtele, C.; Pinna, L. A.; Olsufyeva, E. N.; Preobrazhenskaya, M. N. 2018 2018-10-15 PMC N PMC7088347 30472959.0 10.1134/s0006297918100073 ijy0canp 0.453110 Kumar_2016, Lin_L_2019, Blank_2017, Fung_2017, Yang_2010 Grazioso_2012, van_der_Linden_2014, Lee_C_2019
313 Plackal_George_2014 Bioassay Directed Isolation and Biological Evaluation of Compounds Isolated from Rubus fairholmianus Gard. Plackal George, Blassan; Thangaraj, Parimelazhagan; Sulaiman, Cheruthazhakkatt; Piramanayagam, Shanmughavel; Ramaswamy, Sathish Kumar 2014 2014-09-01 COMM-USE N PMC4165380 25254204.0 10.1155/2014/204340 uk7eisr6 0.452345 Zakaryan_2017, Berkhout_2006, Naito_2007, Dong_2008 Li_W_2011, Lee_C_2020, Park_2017, Zhang_2008
314 Ibrahim_2017 Anti-oxidant and Anti-Inflammatory Cyclic Diarylheptanoids from Alnus japonica Stem Bark R.M. Ibrahim, Sabrin; A. Mohamed, Gamal; I. M. Khedr, Amgad; M. Aljaeid, Bader 2017 2017-01-01 COMM-USE N PMC5963649 29844779.0 hbhunygk 0.452101 Abou-Hamdan_2018, David_2013, Largo_2016, Choudhury_2011 Li_X_2019, Li_W_2011, Park_2017, Cheng_2014
315 Hu_J_2017 A novel benzo-heterocyclic amine derivative N30 inhibits influenza virus replication by depression of Inosine-5’-Monophospate Dehydrogenase activity Hu, Jin; Ma, Linlin; Wang, Huiqiang; Yan, Haiyan; Zhang, Dajun; Li, Zhuorong; Jiang, Jiandong; Li, Yuhuan 2017 2017-03-15 COMM-USE N PMC5353780 28298229.0 10.1186/s12985-017-0724-6 crj0yqmx 0.451729 Tallmadge_2008, Lu_P_2016, Yasui_2016, Meyerson_2017, Ryu_W_2017 Grazioso_2012, Tonelli_2017, Valle-Casuso_2020, Xiong_2020
316 Łoczechin_2019 Functional Carbon Quantum Dots as Medical Countermeasures to Human Coronavirus Łoczechin, Aleksandra; Séron, Karin; Barras, Alexandre; Giovanelli, Emerson; Belouzard, Sandrine; Chen, Yen-Ting; Metzler-Nolte, Nils; Boukherroub, Rabah; Dubuisson, Jean; Szunerits, Sabine 2019 2019-10-21 None N PMC7075527 31633330.0 10.1021/acsami.9b15032 7jz3qpcw 0.449020 Naito_2007, Rice_1992, Volmer_2010, Berkhout_2006, den_Boon_2010 Nazmi_2010, Al‐Bari_2017, Wang_2014, Park_2019
317 Ye_X_2017 Antiproliferative cyclodepsipeptides from the marine actinomycete Streptomyces sp. P11-23B downregulating the tumor metabolic enzymes of glycolysis, glutaminolysis, and lipogenesis Ye, Xuewei; Anjum, Komal; Song, Tengfei; Wang, Wenling; Liang, Ying; Chen, Mengxuan; Huang, Haocai; Lian, Xiao-Yuan; Zhang, Zhizhen 2017 2017-03-31 PMC N PMC7111624 28049552.0 10.1016/j.phytochem.2016.12.010 bn8440sg 0.447589 Berkhout_2006, Haasnoot_2010, Bie_C_2016, Trobaugh_2017, Blank_2017 Grazioso_2012, Xie_J_2018, Tabares_2011
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320 Hwang_2008 Rapid identification of inhibitors that interfere with poliovirus replication using a cell-based assay Hwang, Yu-Chen; Chu, Justin Jang-Hann; Yang, Priscilla L.; Chen, Wilfred; Yates, Marylynn V. 2008 2008-03-31 PMC N PMC7114228 18243348.0 10.1016/j.antiviral.2007.12.009 7q0lrfvd 0.444998 Naito_2007, Brake_2008, Liu_Y_2008, Zhang_2007, Meng_2008 van_der_Linden_2014, Lee_C_2019
321 Yu_M_2012 Identification of myricetin and scutellarein as novel chemical inhibitors of the SARS coronavirus helicase, nsP13 Yu, Mi-Sun; Lee, June; Lee, Jin Moo; Kim, Younggyu; Chin, Young-Won; Jee, Jun-Goo; Keum, Young-Sam; Jeong, Yong-Joo 2012 2012-06-15 PMC N PMC7127438 22578462.0 10.1016/j.bmcl.2012.04.081 72myxp9t 0.443868 Meyerson_2017, Stork_2011, Ban_J_2018, Kang_2009, Yasuda-Inoue_2013 Yap_Y_2005, Sidhu_1996, Zhu_L_2011
322 Zhao_2016 In vitro antimicrobial activities of animal-used quinoxaline 1,4-di-N-oxides against mycobacteria, mycoplasma and fungi Zhao, Yan; Cheng, Guyue; Hao, Haihong; Pan, Yuanhu; Liu, Zhenli; Dai, Menghong; Yuan, Zonghui 2016 2016-09-06 COMM-USE N PMC5011961 27600955.0 10.1186/s12917-016-0812-7 wonwes6p 0.443530 Brucker_2020, Nicholson_2014, Shin_1993, Sereinig_2006, Wrammert_2011 Nie_L_2020, Choi_2016, Choi_2017, Gondim_2019
323 Zou_G_2009 A single-amino acid substitution in West Nile virus 2K peptide between NS4A and NS4B confers resistance to lycorine, a flavivirus inhibitor Zou, Gang; Puig-Basagoiti, Francesc; Zhang, Bo; Qing, Min; Chen, Liqiang; Pankiewicz, Krzysztof W.; Felczak, Krzysztof; Yuan, Zhiming; Shi, Pei-Yong 2009 2009-02-05 None N PMC5388927 19062063.0 10.1016/j.virol.2008.11.003 lbjwyyl1 0.442874 Tallmadge_2008, Meyerson_2017, Kang_2009, Li_C_2014, Ryu_W_2017 Valle-Casuso_2020, Wilde_2019, Terasaki_2016
324 Gündüz_2012 Ethyl 4-(5-bromo-1H-indol-3-yl)-2,6,6-trimethyl-5-oxo-1,4,5,6,7,8-hexa­hydro­quinoline-3-carboxyl­ate Gündüz, Miyase Gözde; Butcher, Ray J.; Öztürk Yildirim, Sema; El-Khouly, Ahmed; Şafak, Cihat; Şimşek, Rahime 2012 2012-11-24 COMM-USE N PMC3588994 23476230.0 10.1107/s1600536812046909 h45zlv8f 0.442139 Abou-Hamdan_2018, Largo_2016, David_2013, Choudhury_2011 Pomeisl_2019, Głowacka_2015, Tabuchi_2009, Tsoukala_2010
325 Yoo_J_2011 Trimethylaurintricarboxylic acid inhibits human DNA methyltransferase 1: insights from enzymatic and molecular modeling studies Yoo, Jakyung; Medina-Franco, José L. 2011 2011-07-30 PMC N PMC7087970 21805123.0 10.1007/s00894-011-1191-4 3h3ald0l 0.441844 Blank_2017, Choudhury_2017, Naito_2007, Yan_J_2007, Haasnoot_2010 Yoo_J_2012, Grazioso_2012
326 Nguyen_2013 In Vitro Evaluation of Novel Inhibitors against the NS2B-NS3 Protease of Dengue Fever Virus Type 4 Nguyen, Thi Thanh Hanh; Lee, Sun; Wang, Hsi-Kai; Chen, Hsin-Yen; Wu, Ying-Ta; Lin, Simon C.; Kim, Do-Won; Kim, Doman 2013 2013-12-13 COMM-USE N PMC6269914 24352016.0 10.3390/molecules181215600 z5w56zeq 0.441614 Naito_2007, Yang_2010, Ramajayam_2010, Liu_Y_2008, Vaughan_2012 Zhu_X_2015, van_der_Linden_2014, Chen_2012, Lee_C_2019
327 HUANG_2013 A new Amaryllidaceae alkaloid from the bulbs of Lycoris radiata HUANG, Sheng-Dian; ZHANG, Yu; HE, Hong-Ping; LI, Shi-Fei; TANG, Gui-Hua; CHEN, Duo-Zhi; CAO, Ming-Ming; DI, Ying-Tong; HAO, Xiao-Jiang 2013 2013-07-31 PMC N PMC7129748 23845551.0 10.1016/s1875-5364(13)60060-6 1flxylyn 0.440050 Choudhury_2011, Abou-Hamdan_2018, Largo_2016, David_2013, Powers_2016 Li_X_2019, Park_2017, Ren_Z_2010, Xie_J_2018
328 Ravindranath_2006 Epicatechins Purified from Green Tea (Camellia sinensis) Differentially Suppress Growth of Gender-Dependent Human Cancer Cell Lines Ravindranath, Mepur H.; Saravanan, Thiruverkadu S.; Monteclaro, Clarence C.; Presser, Naftali; Ye, Xing; Selvan, Senthamil R.; Brosman, Stanley 2006 2006-04-25 PMC N PMC1475929 16786054.0 10.1093/ecam/nel003 x7wg7e9s 0.438661 Bie_C_2016, Zhang_2007, Sweeny_2012, Li_X_2017 Chia_2010, Tayarani-Najaran_2011, Lee_C_2020, Park_2017
329 Guo_H_2005 Novel cyclophilin D inhibitors derived from quinoxaline exhibit highly inhibitory activity against rat mitochondrial swelling and Ca(2+) uptake/release Guo, Hong-xia; Wang, Feng; Yu, Kun-qian; Chen, Jing; Bai, Dong-lu; Chen, Kai-xian; Shen, Xu; Jiang, Hua-liang 2005 2005-10-23 PMC N PMC7091716 16174436.0 10.1111/j.1745-7254.2005.00189.x osbuqzob 0.435841 Chan_2016, Smith_2003, Ospina_2011, Naito_2007, Ivarsson_2012 Li_J_2006, Grazioso_2012, Basak_2009, Li_J_2006
330 de_Wilde_2018 Cyclophilins and cyclophilin inhibitors in nidovirus replication de Wilde, Adriaan H.; Pham, Uyen; Posthuma, Clara C.; Snijder, Eric J. 2018 2018-09-30 PMC N PMC7112023 30014857.0 10.1016/j.virol.2018.06.011 na4y4n9u 0.435815 Ryu_W_2017, Yasuda-Inoue_2013, Liu_X_2013, Taschuk_2020 Zhou_2012, Wilde_2019, Watashi_2007, Peel_2013
331 Ghosh_2015 Organic Carbamates in Drug Design and Medicinal Chemistry Ghosh, Arun K.; Brindisi, Margherita 2015 2015-01-07 PMC N PMC4393377 25565044.0 10.1021/jm501371s o8rlqsq5 0.435744 Mlostoń_2010, Fang_2019, Bozorov_2019, Dive_2007 Bozorov_2019, Ramajayam_2010, Kryshchyshyn_2018
332 McGrath_2013 First generation inhibitors of the adenovirus proteinase McGrath, William J.; Graziano, Vito; Zabrocka, Katarzyna; Mangel, Walter F. 2013 2013-05-24 PMC N PMC3810942 23711373.0 10.1016/j.febslet.2013.05.033 esnjtrsq 0.434069 Naito_2007, Yang_2010, Volmer_2010, UNKNOWN_1987, Pong_2011 Kuo_C_2008, van_der_Linden_2014, Zhu_X_2015, Galasiti_Kankanamalage_2018
333 Tonelli_2017 Host dihydrofolate reductase (DHFR)-directed cycloguanil analogues endowed with activity against influenza virus and respiratory syncytial virus Tonelli, Michele; Naesens, Lieve; Gazzarrini, Sabrina; Santucci, Matteo; Cichero, Elena; Tasso, Bruno; Moroni, Anna; Costi, Maria Paola; Loddo, Roberta 2017 2017-07-28 PMC N PMC7115580 28477572.0 10.1016/j.ejmech.2017.04.070 51yq1rdo 0.434019 Yasui_2016, Schwartz_2007, Tallmadge_2008, Naito_2007, Wrammert_2011 Grazioso_2012, Sidhu_1996, Opsenica_2011, Hu_J_2017
334 Khan_2013 Design, Synthesis, Evaluation and Thermodynamics of 1-Substituted Pyridylimidazo[1,5-a]Pyridine Derivatives as Cysteine Protease Inhibitors Khan, Mohd Sajid; Baig, Mohd Hassan; Ahmad, Saheem; Siddiqui, Shapi Ahmad; Srivastava, Ashwini Kumar; Srinivasan, Kumar Venkatraman; Ansari, Irfan A. 2013 2013-08-05 COMM-USE N PMC3734177 23940536.0 10.1371/journal.pone.0069982 mfy5ln8w 0.433701 Naito_2007, Berkhout_2006, Ivarsson_2012, Chan_2016, Callison_1999 Grazioso_2012, Konno_2013, Thanigaimalai_2013, Thanigaimalai_2013
335 Nguyen_2014 Inhibition effect of flavonoid compounds against neuraminidase expressed in Pichia pastoris Nguyen, Thi Thanh Hanh; Kang, Hee-Kyoung; Kim, Young-Min; Jang, Tae-Su; Kim, Doman 2014 2014-03-11 PMC N PMC7091146 10.1007/s12257-013-0599-3 csfwvpaz 0.433444 Yang_2010, Abraham_1990, Kang_2009, Pong_2011, Meyerson_2017 Xie_J_2018, Sidhu_1996, Xu_Q_2018, Cheng_2014
336 Santos_2003 Synthesis and antiviral activity of sulfated and acetylated derivatives of 2β,3α-dihydroxy-5α-cholestane Santos, Gustavo A.Garrido; Murray, Ana P.; Pujol, Carlos A.; Damonte, Elsa B.; Maier, Marta S. 2003 2003-02-28 PMC N PMC7157925 12606002.0 10.1016/s0039-128x(02)00166-6 8lz70k1x 0.433028 Nadaraia_2018, Abou-Hamdan_2018, Largo_2016, Choudhury_2011 Rauvolfova_2008, Tsoukala_2010, Manta_2009, Głowacka_2015
337 Wild_2016 Functionalized N,N-Diphenylamines as Potent and Selective EPAC2 Inhibitors Wild, Christopher\nT.; Zhu, Yingmin; Na, Ye; Mei, Fang; Ynalvez, Marcus\nA.; Chen, Haiying; Cheng, Xiaodong; Zhou, Jia 2016 2016-03-30 PMC N PMC4867506 27190593.0 10.1021/acsmedchemlett.5b00477 cq298o4z 0.432819 Ivarsson_2012, Smith_2003, Naito_2007, Blank_2017, Tosoni_2015 Grazioso_2012, Pérez-Faginas_2011, Kumarapperuma_2007, Duque_2009
338 Barnard_2008 Is the anti-psychotic, 10-(3-(dimethylamino)propyl)phenothiazine (promazine), a potential drug with which to treat SARS infections? Lack of efficacy of promazine on SARS-CoV replication in a mouse model Barnard, Dale L.; Day, Craig W.; Bailey, Kevin; Heiner, Matthew; Montgomery, Robert; Lauridsen, Larry; Jung, Kie-Hoon; Li, Joseph K.-K.; Chan, Paul K.S.; Sidwell, Robert W. 2008 2008-08-31 None N PMC2582943 18423639.0 10.1016/j.antiviral.2007.12.005 envplcno 0.432352 Xu_L_2014, Falzarano_2015, Ishag_2012, Liu_X_2015, Li_C_2013 Saijo_2005, Zhao_2016, Li_J_2006, de_Oliveira_2013
339 Riahi_2009 First synthesis of 4-(arylsulfonyl)phenols by regioselective [3+3] cyclocondensations of 1,3-bis(silyloxy)-1,3-butadienes with 2-arylsulfonyl-3-ethoxy-2-en-1-ones Riahi, Abdolmajid; Shkoor, Mohanad; Fatunsin, Olumide; Lubbe, Mathias; Reinke, Helmut; Langer, Peter 2009 2009-01-07 PMC N PMC7111812 10.1016/j.tetlet.2008.10.097 ft3y2uq6 0.431712 Largo_2016, David_2013, Choudhury_2011, Abou-Hamdan_2018 Paramonova_2017, Tayade_2015, Pomeisl_2019, Hussain_2008
340 Rad-Moghadam_2010 Synthesis of symmetrical and unsymmetrical 3,3-di(indolyl)indolin-2-ones under controlled catalysis of ionic liquids Rad-Moghadam, Kurosh; Sharifi-Kiasaraie, Masoumeh; Taheri-Amlashi, Homayun 2010 2010-03-27 PMC N PMC7111872 10.1016/j.tet.2010.02.017 yjgfo60f 0.431445 MacDonald_2012, Zhao_2017, Yazarians_2017, Largo_2016, David_2013 Pomeisl_2019, Tabuchi_2009, Tsoukala_2010, Lakshman_2014
341 Liang_2006 Novel Five‐Membered Iminocyclitol Derivatives as Selective and Potent Glycosidase Inhibitors: New Structures for Antivirals and Osteoarthritis Liang, Pi‐Hui; Cheng, Wei‐Chieh; Lee, Yi‐Ling; Yu, Han‐Pang; Wu, Ying‐Ta; Lin, Yi‐Ling; Wong, Chi‐Huey 2006 2006-01-05 PMC N PMC7161998 16397876.0 10.1002/cbic.200500321 412qre64 0.429615 Lu_P_2016, Tallmadge_2008, Yasui_2016, Walker_2010, Crowe_2014
342 Tonelli_2009 Antiviral and cytotoxic activities of aminoarylazo compounds and aryltriazene derivatives Tonelli, Michele; Vazzana, Iana; Tasso, Bruno; Boido, Vito; Sparatore, Fabio; Fermeglia, Maurizio; Paneni, Maria Silvia; Posocco, Paola; Pricl, Sabrina; Colla, Paolo La; Ibba, Cristina; Secci, Barbara; Collu, Gabriella; Loddo, Roberta 2009 2009-07-01 PMC N PMC7127694 19482481.0 10.1016/j.bmc.2009.05.020 29ljbl7g 0.427919 Naito_2007, Haqshenas_2007, Volmer_2010, Schwartz_2007, Tallmadge_2008 Cihan-Üstündağ_2019, Cihan-Üstündağ_2016, Hamada_2013, Lin_J_2008
343 Mlostoń_2010 Synthesis of β-amino-α-trifluoromethyl alcohols and their applications in organic synthesis Mlostoń, Grzegorz; Obijalska, Emilia; Heimgartner, Heinz 2010 2010-08-31 PMC N PMC7125969 10.1016/j.jfluchem.2010.05.014 b3ukefxq 0.425562 MacDonald_2012, Yazarians_2017, Ghosh_2015, Kale_2010 Paramonova_2017, Lin_Z_2012, Kasthuri_2011, Tayade_2015
344 Sydnes_2006 Synthesis of glutamic acid and glutamine peptides possessing a trifluoromethyl ketone group as SARS-CoV 3CL protease inhibitors Sydnes, Magne O.; Hayashi, Yoshio; Sharma, Vinay K.; Hamada, Takashi; Bacha, Usman; Barrila, Jennifer; Freire, Ernesto; Kiso, Yoshiaki 2006 2006-09-04 None N PMC7111793 10.1016/j.tet.2006.06.052 mf0k7h27 0.423912 Largo_2016, Abou-Hamdan_2018, Choudhury_2011, David_2013, Yang_2010 Rauvolfova_2008, Grazioso_2012, Głowacka_2015, Tsoukala_2010
345 Zhong_2012 Antioxidant and antiviral activities of lipophilic epigallocatechin gallate (EGCG) derivatives Zhong, Ying; Ma, Chao-Mei; Shahidi, Fereidoon 2012 2012-01-31 PMC N PMC7105014 10.1016/j.jff.2011.08.003 43farr7l 0.423411 Schmidt_1982, Cai_Y_2004, Xu_X_2016, Zakaryan_2017 Cheng_2014, Nie_L_2020, Park_2017, Zhou_2014
346 De_Clercq_2019 New Nucleoside Analogues for the Treatment of Hemorrhagic Fever Virus Infections De Clercq, Erik 2019 2019-08-07 PMC N PMC7159701 31389664.0 10.1002/asia.201900841 rmxin1da 0.423146 Naito_2007, Zhou_2011, Payne_2017, Callison_1999, Stork_2011
347 He_J_2012 Amaryllidaceae alkaloids inhibit nuclear‐to‐cytoplasmic export of ribonucleoprotein (RNP) complex of highly pathogenic avian influenza virus H5N1 He, Jun; Qi, Wen‐Bao; Wang, Lei; Tian, Jin; Jiao, Pei‐Rong; Liu, Guo‐Qian; Ye, Wen‐Cai; Liao, Ming 2012 2012-11-08 PMC N PMC4634243 23136954.0 10.1111/irv.12035 2qmfs5dl 0.422904 Tallmadge_2008, Ryu_W_2017, Meyerson_2017, Volmer_2010, Stork_2011 Valle-Casuso_2020, Sidhu_1996, Chathuranga_2019
348 Seniya_2014 Analyzing the interaction of a herbal compound Andrographolide from Andrographis paniculata as a folklore against swine flu (H1N1) Seniya, Chandrabhan; Shrivastava, Shilpi; Singh, Sanjay Kumar; Khan, Ghulam Jilani 2014 2014-09-30 PMC N 10.1016/s2222-1808(14)60692-7 22vlqzzh 0.422543 Smith_2003, Naito_2007, Ivarsson_2012, Chan_2016, Callison_1999 Nie_L_2020, Xie_J_2018, Xuan_2016, Lee_C_2020
349 Grujić_2002 Aminopeptidase inhibitors bestatin and actinonin inhibit cell proliferation of myeloma cells predominantly by intracellular interactions Grujić, Mirjana; Renko, Metka 2002 2002-08-28 PMC N PMC7127609 12048155.0 10.1016/s0304-3835(02)00086-1 8za4gynz 0.422209 Bie_C_2016, Liu_J_2007, Zhang_2007, Greene_2012 Sidhu_1996, Li_L_2012, Chen_2019, Grazioso_2012
350 Obeid_2011 Inhibition of hepatitis C virus replication by semi-synthetic derivatives of glycopeptide antibiotics Obeid, Susan; Printsevskaya, Svetlana S.; Olsufyeva, Eugenia N.; Dallmeier, Kai; Durantel, David; Zoulim, Fabien; Preobrazhenskaya, Maria N.; Neyts, Johan; Paeshuyse, Jan 2011 2011-03-24 PMC N PMC7109641 21436155.0 10.1093/jac/dkr104 slnde4dc 0.420995 Tallmadge_2008, Rice_1992, Stork_2011, Kang_2009, Naito_2007 Zhou_2012, Matsumoto_2013, Sidhu_1996, Lee_C_2019
351 Fioravanti_2008 Solution-phase synthesis of 2-cyano and 2-amido aziridinyl peptides Fioravanti, Stefania; Massari, Davide; Morreale, Alberto; Pellacani, Lucio; Tardella, Paolo A. 2008 2008-03-31 PMC N PMC7111778 10.1016/j.tet.2008.01.098 gqj790lp 0.420749 MacDonald_2012, Yazarians_2017, Bouton_2017, Kale_2010 Paramonova_2017, Lin_Z_2012, Tayade_2015, Kasthuri_2011
352 Kale_2010 Facile route for N 1-aryl benzotriazoles from diazoamino arynes via CuI-mediated intramolecular N-arylation Kale, Raju R.; Prasad, Virendra; Hussain, H.A.; Tiwari, Vinod K. 2010 2010-10-27 PMC N PMC7111836 10.1016/j.tetlet.2010.08.083 gyw1vezs 0.420265 MacDonald_2012, Yazarians_2017, Lin_Z_2012, Mlostoń_2010 Lin_Z_2012, Paramonova_2017, Tayade_2015, Sobenina_2018
353 Hour_2013 Baicalein, Ethyl Acetate, and Chloroform Extracts of Scutellaria baicalensis Inhibit the Neuraminidase Activity of Pandemic 2009 H1N1 and Seasonal Influenza A Viruses Hour, Mann-Jen; Huang, Su-Hua; Chang, Ching-Yao; Lin, Yen-Kuan; Wang, Ching-Ying; Chang, Yuan-Shiun; Lin, Cheng-Wen 2013 2013-06-20 COMM-USE N PMC3705751 23864896.0 10.1155/2013/750803 bj7bfis8 0.420020 Yasui_2016, Tallmadge_2008, McCutcheon_1995, Kedik_2009 Yang_2014, Chang_2014, Chathuranga_2019, Ren_Z_2010
354 Pérard-Viret_2017 Chapter Four Cephalotaxus Alkaloids Pérard-Viret, Joëlle; Quteishat, Laith; Alsalim, Rana; Royer, Jacques; Dumas, Françoise 2017 2017-12-31 PMC N PMC7110560 28838429.0 10.1016/bs.alkal.2017.07.001 m3mhj6op 0.419235 Berkhout_2006, Naito_2007, Dolja_2006, WU_L_2015, Callison_1999 Xuan_2016, Teoh_2015, Gondim_2019, Bastida_2006
355 Gong_2019 Inhibitory effects of homoharringtonine on foot and mouth disease virus in vitro Gong, Mei‐jiao; Li, Shi‐fang; Xie, Yin‐li; Zhao, Fu‐rong; Shao, Jun‐jun; Zhang, Yong‐guang; Wang, Wen‐hui; Chang, Hui‐yun 2019 2019-05-29 PMC N PMC7166808 31032977.0 10.1002/jmv.25494 7q9h92le 0.418266 Berkhout_2006, Volmer_2010, Yasui_2016, Naito_2007, Ban_J_2018
356 Yang_2010 Identification of phenanthroindolizines and phenanthroquinolizidines as novel potent anti-coronaviral agents for porcine enteropathogenic coronavirus transmissible gastroenteritis virus and human severe acute respiratory syndrome coronavirus Yang, Cheng-Wei; Lee, Yue-Zhi; Kang, Iou-Jiun; Barnard, Dale L.; Jan, Jia-Tsrong; Lin, Du; Huang, Chun-Wei; Yeh, Teng-Kuang; Chao, Yu-Sheng; Lee, Shiow-Ju 2010 2010-11-30 None N PMC7114283 20727913.0 10.1016/j.antiviral.2010.08.009 zkrlyyu9 0.417900 Naito_2007, Volmer_2010, Berkhout_2006, Yasui_2016, Rice_1992 Valle-Casuso_2020, Chathuranga_2019, Nie_L_2020
357 Chen_2012 Anti-HIV-1 Activity of a New Scorpion Venom Peptide Derivative Kn2-7 Chen, Yaoqing; Cao, Luyang; Zhong, Maohua; Zhang, Yan; Han, Chen; Li, Qiaoli; Yang, Jingyi; Zhou, Dihan; Shi, Wei; He, Benxia; Liu, Fang; Yu, Jie; Sun, Ying; Cao, Yuan; Li, Yaoming; Li, Wenxin; Guo, Deying; Cao, Zhijian; Yan, Huimin 2012 2012-04-19 COMM-USE N PMC3334916 22536342.0 10.1371/journal.pone.0034947 6sx9fbwf 0.416965 Tallmadge_2008, Yasui_2016, Jiang_2006, Naito_2007, Lu_P_2016 Zhu_X_2015, Lee_C_2019, Zhong_2005, Ren_Z_2010
358 Park_2012 Tanshinones as selective and slow-binding inhibitors for SARS-CoV cysteine proteases Park, Ji-Young; Kim, Jang Hoon; Kim, Young Min; Jeong, Hyung Jae; Kim, Dae Wook; Park, Ki Hun; Kwon, Hyung-Jun; Park, Su-Jin; Lee, Woo Song; Ryu, Young Bae 2012 2012-10-01 PMC N PMC7127169 22884354.0 10.1016/j.bmc.2012.07.038 i4rldhz2 0.415617 Ramajayam_2010, Naito_2007, Li_C_2017, Yang_2010, Berkhout_2006 Zhu_L_2011, Yap_Y_2005, Lee_H_2013, Liu_W_2014
359 Lin_P_2008 A stable trypsin inhibitor from Chinese dull black soybeans with potentially exploitable activities Lin, Peng; Ng, Tzi Bun 2008 2008-09-30 PMC N PMC7108285 10.1016/j.procbio.2008.05.005 kwmm0z48 0.415499 Yang_2010, Luo_K_1996, Welling_1987, Zhang_2007 Li_M_2017, Xie_J_2018, Hong_2013
360 Kim_J_2017 Antiviral escin derivatives from the seeds of Aesculus turbinata Blume (Japanese horse chestnut) Kim, Ji Won; Ha, Thi-Kim-Quy; Cho, Hyomoon; Kim, Eunhee; Shim, Sang Hee; Yang, Jun-Li; Oh, Won Keun 2017 2017-07-01 PMC N PMC7127610 28527823.0 10.1016/j.bmcl.2017.05.022 84u3c33m 0.414982 Berkhout_2006, Naito_2007, Bright_2016, Callison_1999, Volmer_2010 Chathuranga_2019, Nie_L_2020, Cui_Q_2018, Wu_H_2016
361 Kryshchyshyn_2018 Thiopyrano[2,3-d]Thiazoles as New Efficient Scaffolds in Medicinal Chemistry Kryshchyshyn, Anna; Roman, Olexandra; Lozynskyi, Andrii; Lesyk, Roman 2018 2018-06-14 COMM-USE N PMC6027677 29903979.0 10.3390/scipharm86020026 qohx5eyg 0.413903 Park_2012, Weber_2009, Sztuba-Solinska_2019, Bassetto_2016, Zoete_2009 Bozorov_2019, Grazioso_2012, Sahoo_2016, Carbone_2013
362 McNulty_2015 iPSC Neuronal Assay Identifies Amaryllidaceae Pharmacophore with Multiple Effects against Herpesvirus Infections McNulty, James; D’Aiuto, Leonardo; Zhi, Yun; McClain, Lora; Zepeda-Velázquez, Carlos; Ler, Spencer; Jenkins, Hilary A.; Yee, Michael B.; Piazza, Paolo; Yolken, Robert H.; Kinchington, Paul R.; Nimgaonkar, Vishwajit L. 2015 2015-12-01 PMC N PMC4716588 26819664.0 10.1021/acsmedchemlett.5b00318 7z2pfqfb 0.413376 Davaro_2013, Tallmadge_2008, Garcia–Moliner_2013, Crowe_2014 Ren_Z_2010, Sidhu_1996, Zhu_X_2015, Novikov_2013
363 Zhao_2010 A high-throughput screening system for G-protein-coupled receptors using β-lactamase enzyme complementation technology Zhao, Chuan-ke; Yin, Qi; Li, Shi-you 2010 2010-11-22 PMC N PMC4002942 21102483.0 10.1038/aps.2010.154 l7igrhsg 0.412886 Rajagopala_2015, Brake_2008, Naito_2007, Tsai_2013, Goradia_1988 Grazioso_2012, Rimstad_1995, Gabrilovac_2005, Kong_2008
364 Cho_J_2013 Geranylated flavonoids displaying SARS-CoV papain-like protease inhibition from the fruits of Paulownia tomentosa Cho, Jung Keun; Curtis-Long, Marcus J.; Lee, Kon Ho; Kim, Dae Wook; Ryu, Hyung Won; Yuk, Heung Joo; Park, Ki Hun 2013 2013-06-01 PMC N PMC7126831 23623680.0 10.1016/j.bmc.2013.03.027 q0978e9r 0.411584 Yang_2010, Naito_2007, Kang_2009, Volmer_2010, Vaughan_2012 Grazioso_2012, Xie_J_2018, Park_2017
365 Haviernik_2018 Arbidol (Umifenovir): A Broad-Spectrum Antiviral Drug That Inhibits Medically Important Arthropod-Borne Flaviviruses Haviernik, Jan; Štefánik, Michal; Fojtíková, Martina; Kali, Sabrina; Tordo, Noël; Rudolf, Ivo; Hubálek, Zdeněk; Eyer, Luděk; Ruzek, Daniel 2018 2018-04-10 COMM-USE N PMC5923478 29642580.0 10.3390/v10040184 4km8usn6 0.410202 Tallmadge_2008, Lu_P_2016, Yasui_2016, Ryu_W_2017, Schwartz_2007 Valle-Casuso_2020, Blaising_2014, Liu_Z_2015, Tian_2017
366 Deaton_2008 Thiol-based angiotensin-converting enzyme 2 inhibitors: P1 modifications for the exploration of the S1 subsite Deaton, David N.; Gao, Enoch N.; Graham, Kevin P.; Gross, Jeffrey W.; Miller, Aaron B.; Strelow, John M. 2008 2008-01-15 PMC N PMC7126659 18078750.0 10.1016/j.bmcl.2007.11.048 gic43uwz 0.408978 Deaton_2008, Zhao_2008, Ramajayam_2010, Tikellis_2012 Deaton_2008, Grazioso_2012, Dude_2008, Zhang_2020
367 Pascual_2017 Discovery of novel non-competitive inhibitors of mammalian neutral M1 aminopeptidase (APN) Pascual, Isel; Valiente, Pedro A.; García, Gabriela; Valdés-Tresanco, Mario E.; Arrebola, Yarini; Díaz, Lisset; Bounaadja, Lotfi; Uribe, Rosa María; Pacheco, Mae Chappé; Florent, Isabelle; Charli, Jean-Louis 2017 2017-11-30 None N PMC7127808 28964831.0 10.1016/j.biochi.2017.09.015 h3pvre4k 0.408749 Ivarsson_2012, Naito_2007, Smith_2003, Yang_2010, Yang_2012 Grazioso_2012, Zhu_X_2015, Basak_2009
368 Jin_Y_2017 The discovery of a novel compound with potent antitumor activity: virtual screening, synthesis, biological evaluation and preliminary mechanism study Jin, Yuanyuan; Li, Linhu; Yang, Zhaoyong; Liu, Mingliang; Guo, Huiyuan; Shen, Weiyi 2017 2017-02-21 COMM-USE N PMC5421875 28445950.0 10.18632/oncotarget.15601 s1p2k9mi 0.407930 Berkhout_2006, Lee_S_2016, Martín-Vicente_2017, Blank_2017, Ban_J_2018 Chen_2019, Tian_2012, Medvedev_2007
369 Lim_H_2016 Inhibitory effect of flavonoids against NS2B-NS3 protease of ZIKA virus and their structure activity relationship Lim, Hee-jung; Nguyen, Thi Thanh Hanh; Kim, Nahyun M.; Park, Jun-Seong; Jang, Tae-Su; Kim, Doman 2016 2016-11-24 PMC N PMC7088272 27885509.0 10.1007/s10529-016-2261-6 fb4eqn3c 0.406580 Choudhury_2011, David_2013, Largo_2016, Abou-Hamdan_2018, Yang_2010 Nguyen_2013, Roy_A_2017, Ishag_2016, Ren_Z_2010
370 Zhao_2019 Research progress in the biological activities of 3,4,5-trimethoxycinnamic acid (TMCA) derivatives Zhao, Zefeng; Song, Huanhuan; Xie, Jing; Liu, Tian; Zhao, Xue; Chen, Xufei; He, Xirui; Wu, Shaoping; Zhang, Yongmin; Zheng, Xiaohui 2019 2019-07-01 PMC N PMC7115657 31009908.0 10.1016/j.ejmech.2019.04.009 01mvhsrk 0.405785 Zakaryan_2017, Weber_2009, Sztuba-Solinska_2019, Liu_A_2012 Bozorov_2019, Sahoo_2016, Cao_Z_2013, Grazioso_2012
371 Lucas-Hourani_2017 Original Chemical Series of Pyrimidine Biosynthesis Inhibitors That Boost the Antiviral Interferon Response Lucas-Hourani, Marianne; Dauzonne, Daniel; Munier-Lehmann, Hélène; Khiar, Samira; Nisole, Sébastien; Dairou, Julien; Helynck, Olivier; Afonso, Philippe V.; Tangy, Frédéric; Vidalain, Pierre-Olivier 2017 2017-09-22 None N PMC5610480 28807907.0 10.1128/aac.00383-17 jiqql1pr 0.404056 Berkhout_2006, Haasnoot_2010, Martín-Vicente_2017, Leung_2012 Grazioso_2012, Liu_Q_2020, Hamada_2013
372 Almeida_2011 Marilones A–C, phthalides from the sponge-derived fungus Stachylidium sp. Almeida, Celso; Kehraus, Stefan; Prudêncio, Miguel; König, Gabriele M 2011 2011-12-05 COMM-USE N PMC3252867 22238541.0 10.3762/bjoc.7.192 abkpssnl 0.403612 Yang_2010, Abou-Hamdan_2018, Largo_2016, David_2013, Choudhury_2011 Tian_2015, Xie_J_2018, Tabares_2011, Almeida_2010
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374 Novikov_2013 A highly facile approach to the synthesis of novel 2-(3-benzyl-2,4-dioxo-1,2,3,4-tetrahydropyrimidin-1-yl)-N-phenylacetamides Novikov, Mikhail S.; Babkov, Denis A.; Paramonova, Maria P.; Chizhov, Alexander O.; Khandazhinskaya, Anastasia L.; Seley-Radtke, Katherine L. 2013 2013-02-06 PMC N PMC7111777 10.1016/j.tetlet.2012.11.090 t40fn3bf 0.401046 Naito_2007, Conzelmann_1996, Park_2012, Dykxhoorn_2006 Paramonova_2017, Tayade_2015, Chopade_2016, Riahi_2009
375 Belova_2018 The molecular structure of 4-methylpyridine-N-oxide: Gas-phase electron diffraction and quantum chemical calculations Belova, Natalya V.; Girichev, Georgiy V.; Kotova, Vitaliya E.; Korolkova, Kseniya A.; Trang, Nguyen Hoang 2018 2018-03-15 PMC N PMC7094666 10.1016/j.molstruc.2017.11.070 6vql2u75 0.400492 Karpińska_2013, Puglisi_1990, Bryndal_2019, _2018 Jezierska-Mazzarello_2011, Thomson_2010, Pomeisl_2019, Sahoo_2016
376 Kao_R_2004 Identification of Novel Small-Molecule Inhibitors of Severe Acute Respiratory Syndrome-Associated Coronavirus by Chemical Genetics Kao, Richard Y.; Tsui, Wayne H.W.; Lee, Terri S.W.; Tanner, Julian A.; Watt, Rory M.; Huang, Jian-Dong; Hu, Lihong; Chen, Guanhua; Chen, Zhiwei; Zhang, Linqi; He, Tian; Chan, Kwok-Hung; Tse, Herman; To, Amanda P.C.; Ng, Louisa W.Y.; Wong, Bonnie C.W.; Tsoi, Hoi-Wah; Yang, Dan; Ho, David D.; Yuen, Kwok-Yung 2004 2004-09-30 PMC N PMC7128553 15380189.0 10.1016/j.chembiol.2004.07.013 jgtbp5r6 0.396451 Naito_2007, Kang_2009, Yang_2010, Li_C_2013, Meyerson_2017 Haga_2010, Kao_R_2004, Zhou_2011
377 Alam_2015 Anti-cytomegalovirus activity of the anthraquinone atanyl blue PRL Alam, Zohaib; Al-Mahdi, Zainab; Zhu, Yali; McKee, Zachary; Parris, Deborah S.; Parikh, Hardik I.; Kellogg, Glen E.; Kuchta, Alison; McVoy, Michael A. 2015 2015-02-28 None N PMC4289655 25499125.0 10.1016/j.antiviral.2014.12.003 ey094j4j 0.395458 Compton_2014, Ban_J_2018, Meyerson_2017, Lee_W_2018, Li_C_2014 Sidhu_1996, Hsieh_2010, Wu_H_2016, Zhou_2012
378 Choi_2009 Antiviral activity of quercetin 7-rhamnoside against porcine epidemic diarrhea virus Choi, Hwa-Jung; Kim, Jin-Hee; Lee, Choong-Hwan; Ahn, Young-Joon; Song, Jae-Hyoung; Baek, Seung-Hwa; Kwon, Dur-Han 2009 2009-01-31 PMC N PMC7114206 18992773.0 10.1016/j.antiviral.2008.10.002 ni7qfjk9 0.395306 Yasui_2016, Tallmadge_2008, Lu_P_2016, Naito_2007, Volmer_2010 Hu_H_2019, Zhou_2012, Yang_2014
379 Yoo_J_2012 Molecular Modeling of Inhibitors of Human DNA Methyltransferase with a Crystal Structure Discovery of a Novel DNMT1 Inhibitor Yoo, Jakyung; Kim, Joo Hee; Robertson, Keith D.; Medina-Franco, José L. 2012 2012-12-31 None N PMC3837394 22607757.0 10.1016/b978-0-12-398312-1.00008-1 wcxcb8el 0.395009 Naito_2007, Blank_2017, Choudhury_2017, Tosoni_2015 Yoo_J_2011, Niu_C_2008, Li_J_2006
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381 Klein_2020 New Cysteine Protease Inhibitors: Electrophilic (Het)arenes and Unexpected Prodrug Identification for the Trypanosoma Protease Rhodesain Klein, Philipp; Johe, Patrick; Wagner, Annika; Jung, Sascha; Kühlborn, Jonas; Barthels, Fabian; Tenzer, Stefan; Distler, Ute; Waigel, Waldemar; Engels, Bernd; Hellmich, Ute A.; Opatz, Till; Schirmeister, Tanja 2020 2020-03-23 None N PMC7145299 32210166.0 10.3390/molecules25061451 j3tg4nn2 0.394027 Smith_2003, Chan_2016, Ivarsson_2012, Schlieker_2007, Cleary_2015
382 Boonyasuppayakorn_2014 Amodiaquine, an antimalarial drug, inhibits dengue virus type 2 replication and infectivity Boonyasuppayakorn, Siwaporn; Reichert, Erin D.; Manzano, Mark; Nagarajan, Kuppuswamy; Padmanabhan, Radhakrishnan 2014 2014-06-30 None N PMC4523242 24680954.0 10.1016/j.antiviral.2014.03.014 tiq1uxpn 0.393609 Tallmadge_2008, Meyerson_2017, Rice_1992, Li_C_2014, Stork_2011 Zhou_2012, Valle-Casuso_2020, De_Burghgraeve_2012, Park_2019
383 Oyama_2016 Antibacterial Effects of Glycyrrhetinic Acid and Its Derivatives on Staphylococcus aureus Oyama, Kentaro; Kawada-Matsuo, Miki; Oogai, Yuichi; Hayashi, Tetsuya; Nakamura, Norifumi; Komatsuzawa, Hitoshi 2016 2016-11-07 COMM-USE N PMC5098735 27820854.0 10.1371/journal.pone.0165831 jkjlbki9 0.393491 Siebert_2018, Callison_1999, Hsueh_2005, Yang_2010 Kim_J_2019, Zhao_2016, Abdelhamid_2018, Wu_J_2014
384 Good_2020 Preclinical evaluation of AT-527, a novel guanosine nucleotide prodrug with potent, pan-genotypic activity against hepatitis C virus Good, Steven S.; Moussa, Adel; Zhou, Xiao-Jian; Pietropaolo, Keith; Sommadossi, Jean-Pierre 2020 2020-01-08 COMM-USE N PMC6949113 31914458.0 10.1371/journal.pone.0227104 lxtuig9w 0.390445 Naito_2007, Kang_2009, Meng_2008, Rice_1992, Chevalier_2007 Zhou_2012, Gao_M_2010, Obeid_2011, Zhu_X_2015
385 Zhong_2005 Highly potent anti-HIV-1 activity isolated from fermented Polygonum tinctorium Aiton Zhong, Yu; Yoshinaka, Yoshiyuki; Takeda, Tadahiro; Shimizu, Noriko; Yoshizaki, Sayaka; Inagaki, Yoshio; Matsuda, Shinobu; Honda, Gisho; Fujii, Nobutaka; Yamamoto, Naoki 2005 2005-06-30 PMC N PMC7114116 15911029.0 10.1016/j.antiviral.2005.02.003 z29b30sd 0.389877 Tallmadge_2008, Compton_2014, Volmer_2010, Meyerson_2017, Ban_J_2018 Ren_Z_2010, Yang_2014, Chathuranga_2019, Taherkhani_2013
386 Oli_S_2014 Identification of Plakortide E from the Caribbean Sponge Plakortis halichondroides as a Trypanocidal Protease Inhibitor using Bioactivity-Guided Fractionation Oli, Swarna; Abdelmohsen, Usama Ramadan; Hentschel, Ute; Schirmeister, Tanja 2014 2014-05-02 COMM-USE N PMC4052307 24798927.0 10.3390/md12052614 2l9rl6du 0.389649 Ramajayam_2010, Saura_1999, Pager_2006, Yang_2010, Li_C_2017 Tabares_2011, Grazioso_2012, Pimentel-Elardo_2011, Dude_2008
387 Kuban-Jankowska_2015 Redox process is crucial for inhibitory properties of aurintricarboxylic acid against activity of YopH: virulence factor of Yersinia pestis Kuban-Jankowska, Alicja; Sahu, Kamlesh K; Niedzialkowski, Pawel; Gorska, Magdalena; Tuszynski, Jack A; Ossowski, Tadeusz; Wozniak, Michal 2015 2015-07-22 COMM-USE N PMC4621896 26286963.0 1irvzt8v 0.389626 Smith_2003, Ivarsson_2012, Blank_2017, Yang_2010 Someya_2008, Buller_2012, Xu_Q_2018, Grazioso_2012
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391 Günther_2004 Application of real-time PCR for testing antiviral compounds against Lassa virus, SARS coronavirus and Ebola virus in vitro Günther, Stephan; Asper, Marcel; Röser, Christina; Luna, Luciano K.S.; Drosten, Christian; Becker-Ziaja, Beate; Borowski, Peter; Chen, Huan-Ming; Hosmane, Ramachandra S. 2004 2004-09-30 PMC N PMC7126008 15451189.0 10.1016/j.antiviral.2004.05.001 wys8t1wi 0.387537 Tallmadge_2008, Lu_P_2016, Ryu_W_2017, Yasui_2016, Crowe_2014 Zhou_2012, van_der_Linden_2014, Obeid_2011, Valle-Casuso_2020
392 Hilimire_2017 HIV-1 Frameshift RNA-Targeted Triazoles Inhibit Propagation of Replication-Competent and Multi-Drug-Resistant HIV in Human Cells Hilimire, Thomas\nA.; Chamberlain, Jeffrey M.; Anokhina, Viktoriya; Bennett, Ryan P.; Swart, Oliver; Myers, Jason R.; Ashton, John M.; Stewart, Ryan A.; Featherston, Aaron L.; Gates, Kathleen; Helms, Eric D.; Smith, Harold C.; Dewhurst, Stephen; Miller, Benjamin L. 2017 2017-04-27 None N PMC5477779 28448121.0 10.1021/acschembio.7b00052 xhvk7wxl 0.387212 Berkhout_2006, Naito_2007, Rice_1992, Stork_2011, Trobaugh_2017 Zhu_X_2015, Krumm_2011
393 Mudithanapelli_2018 Highly Efficient and Practical N-Heterocyclic Carbene Organocatalyzed Chemoselective N(1)/C(3)-Functionalization of Isatins with Green Chemistry Principles Mudithanapelli, Chandrashekar; Vasam, Chandra Sekhar; Vadde, Ravinder; Kim, Mi-hyun 2018 2018-12-18 None N PMC6643579 31458364.0 10.1021/acsomega.8b02361 xf7biu18 0.386543 Abou-Hamdan_2018, David_2013, Largo_2016, Choudhury_2011, MacDonald_2012 Pomeisl_2019, Thomson_2010, Tabuchi_2009, Pahonțu_2015
394 Lu_X_2013 In Vitro Activity of Sodium New Houttuyfonate Alone and in Combination with Oxacillin or Netilmicin against Methicillin-Resistant Staphylococcus aureus Lu, Xi; Yang, Xinyi; Li, Xue; Lu, Yun; Ren, Zhitao; Zhao, Longyin; Hu, Xinxin; Jiang, Jiandong; You, Xuefu 2013 2013-07-02 COMM-USE N PMC3699466 23844154.0 10.1371/journal.pone.0068053 esjfhztp 0.385994 Hsueh_2005, Hsueh_2005, Souto_2016, Goldspink_2015 Zhao_2016, Klein_2008, Villacís_2020, Odden_2018
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396 Smith_2010 Inhibition of Heat-Shock Protein 90 Reduces Ebola Virus Replication Smith, Darci R.; McCarthy, Sarah; Chrovian, Andrew; Olinger, Gene; Stossel, Andrea; Geisbert, Thomas W.; Hensley, Lisa E.; Connor, John H. 2010 2010-08-01 PMC N PMC2907434 20452380.0 10.1016/j.antiviral.2010.04.015 lc4qvvou 0.384929 Ban_J_2018, Meyerson_2017, Li_C_2014, Kumar_2016, Tallmadge_2008 Song_2018, Valle-Casuso_2020
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398 Liu_W_2014 Synthesis, modification and docking studies of 5-sulfonyl isatin derivatives as SARS-CoV 3C-like protease inhibitors Liu, Wei; Zhu, He-Min; Niu, Guo-Jun; Shi, En-Zhi; Chen, Jie; Sun, Bo; Chen, Wei-Qiang; Zhou, Hong-Gang; Yang, Cheng 2014 2014-01-01 None N PMC7111328 24316352.0 10.1016/j.bmc.2013.11.028 r0h2zhj2 0.384194 Ramajayam_2010, Li_C_2017, Ban_J_2018, Meyerson_2017, Kuang_2005 Niu_C_2008, Adhikari_2017, Zhu_L_2011, Kuo_C_2008
399 Hassan_2016 Therapeutic potential of coumarins as antiviral agents Hassan, Mohd. Zaheen; Osman, Hasnah; Ali, Mohamed Ashraf; Ahsan, Mohamed Jawed 2016 2016-11-10 PMC N PMC7115672 27484512.0 10.1016/j.ejmech.2016.07.056 ahceohgl 0.384011 Zakaryan_2017, Weber_2009, Li_C_2019, Connelly_2016 Liu_A_2012, Singh_2013, Zhang_2015, Serban_2020
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401 Park_2017 Evaluation of polyphenols from Broussonetia papyrifera as coronavirus protease inhibitors Park, Ji-Young; Yuk, Heung Joo; Ryu, Hyung Won; Lim, Su Hwan; Kim, Kyung Su; Park, Ki Hun; Ryu, Young Bae; Lee, Woo Song 2017 2017-01-22 COMM-USE N PMC6010046 28112000.0 10.1080/14756366.2016.1265519 oz2ztmzo 0.382478 Choudhury_2011, Largo_2016, David_2013, Abou-Hamdan_2018, Yang_2010 Kim_J_2019, Li_X_2019, Zhang_2008, HUANG_2013
402 Gu_L_2012 Novel Virostatic Agents against Bluetongue Virus Gu, Linlin; Musiienko, Volodymyr; Bai, Zhijun; Qin, Aijian; Schneller, Stewart W.; Li, Qianjun 2012 2012-08-15 COMM-USE N PMC3419696 22905259.0 10.1371/journal.pone.0043341 81emqucd 0.381193 Berkhout_2006, Ban_J_2018, Volmer_2010, Meyerson_2017, Trobaugh_2017 Wu_H_2016, Sidhu_1996, Zhong_2009, Park_2019
403 de_la_Guardia_2018 Antiviral Activity of Novel Quinoline Derivatives against Dengue Virus Serotype 2 de la Guardia, Carolina; Stephens, David E.; Dang, Hang T.; Quijada, Mario; Larionov, Oleg V.; Lleonart, Ricardo 2018 2018-03-16 COMM-USE N PMC5997395 29547522.0 10.3390/molecules23030672 nnedgexs 0.380875 Berkhout_2006, Lu_P_2016, Volmer_2010, Naito_2007, Yasui_2016 Lee_C_2019, Zhou_2012, Valle-Casuso_2020, Liu_Z_2015
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406 Opsenica_2011 A chemotype that inhibits three unrelated pathogenic targets: the botulinum neurotoxin serotype A light chain, P. falciparum malaria, and the Ebola filovirus Opsenica, Igor; Burnett, James C.; Gussio, Rick; Opsenica, Dejan; Todorović, Nina; Lanteri, Charlotte A.; Sciotti, Richard J.; Gettayacamin, Montip; Basilico, Nicoletta; Taramelli, Donatella; Nuss, Jonathan E.; Wanner, Laura; Panchal, Rekha G.; Šolaja, Bogdan A.; Bavari, Sina 2011 2011-03-10 PMC N PMC3056319 21265542.0 10.1021/jm100938u eamctnik 0.380404 Naito_2007, Berkhout_2006, Volmer_2010, O’Brien_2007, Shaw_2011 Grazioso_2012, Lee_C_2019, Kuo_C_2008, Zhao_2016
407 Yoon_2019 Study on the 2‐Phenylchroman‐4‐One Derivatives and their anti‐MERS‐CoV Activities Yoon, Ji Hye; Lee, Jihye; Lee, Jun Young; Shin, Young Sup; Kim, Dong Eon; Min, Jung Sun; Park, Chul Min; Song, Jong Hwan; Kim, Seungtaek; Kwon, Sunoh; Jang, Min Seong; Kim, Hyoung Rae 2019 2019-07-28 PMC N PMC7161870 10.1002/bkcs.11832 qg3hl5ft 0.380051 Gogineni_2015, Hjortland_2016, Mao_H_2019, Alqahtani_2016, Lee_J_2016
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413 Müller_2020 Comparison of broad-spectrum antiviral activities of the synthetic rocaglate CR-31-B (−) and the eIF4A-inhibitor Silvestrol Müller, Christin; Obermann, Wiebke; Schulte, Falk W.; Lange-Grünweller, Kerstin; Oestereich, Lisa; Elgner, Fabian; Glitscher, Mirco; Hildt, Eberhard; Singh, Kamini; Wendel, Hans-Guido; Hartmann, Roland K.; Ziebuhr, John; Grünweller, Arnold 2020 2020-03-31 None N PMC7114339 31931103.0 10.1016/j.antiviral.2020.104706 uztke3jt 0.374479 Stork_2011, Meyerson_2017, Kang_2009, Berkhout_2006, Yasuda-Inoue_2013 Grazioso_2012, Liu_Q_2020, Sidhu_1996, Müller_2018
414 Borges-Argáez_2019 In vitro evaluation of anthraquinones from Aloe vera (Aloe barbadensis Miller) roots and several derivatives against strains of influenza virus Borges-Argáez, Rocío; Chan-Balan, Reyna; Cetina-Montejo, Lisseth; Ayora-Talavera, Guadalupe; Sansores-Peraza, Pablo; Gómez-Carballo, Jesús; Cáceres-Farfán, Mirbella 2019 2019-06-30 PMC N PMC7138392 10.1016/j.indcrop.2019.02.056 lxif1uxw 0.373600 Yang_2010, Volmer_2010, Haqshenas_2007, Shen_2005, Li_C_2013 Nie_L_2020, Chathuranga_2019, Ren_Z_2010, Zhao_2016
415 Ohnishi_2019 Evaluation of a non-prime site substituent and warheads combined with a decahydroisoquinolin scaffold as a SARS 3CL protease inhibitor Ohnishi, Kouji; Hattori, Yasunao; Kobayashi, Kazuya; Akaji, Kenichi 2019 2019-01-15 PMC N PMC7126642 30558861.0 10.1016/j.bmc.2018.12.019 960th627 0.372940 Smith_2003, Ivarsson_2012, Schlieker_2007, Yang_2010, Vaughan_2012 Yoshizawa_2020, Shimamoto_2015, Konno_2013, Thanigaimalai_2013
416 Baddeley_2012 1,3-Diphenyl-4,5-dihydro-1H-pyrazol-5-one Baddeley, Thomas C.; Wardell, Solange M. S. V.; Tiekink, Edward R. T.; Wardell, James L. 2012 2012-03-10 COMM-USE N PMC3343981 22589890.0 10.1107/s1600536812009567 dg90gulb 0.372557 Abou-Hamdan_2018, Choudhury_2011, David_2013, Largo_2016 Gündüz_2012, Pomeisl_2019, Głowacka_2015, Tsoukala_2010
417 Yuan_2019 Screening of an FDA-Approved Drug Library with a Two-Tier System Identifies an Entry Inhibitor of Severe Fever with Thrombocytopenia Syndrome Virus Yuan, Shuofeng; Chan, Jasper Fuk-Woo; Ye, Zi-Wei; Wen, Lei; Tsang, Terance Gi-Wai; Cao, Jianli; Huang, Jingjing; Chan, Chris Chun-Yiu; Chik, Kenn Ka-Heng; Choi, Garnet Kwan-Yue; Cai, Jian-Piao; Yin, Feifei; Chu, Hin; Liang, Mifang; Jin, Dong-Yan; Yuen, Kwok-Yung 2019 2019-04-25 COMM-USE N PMC6520937 31027241.0 10.3390/v11040385 i37tj2u6 0.372402 Naito_2007, Berkhout_2006, Compton_2014, Tallmadge_2008, Volmer_2010 Shimada_2015
418 Fan_D_2016 Triterpenoids from the stems of Tripterygium regelii Fan, Dongsheng; Parhira, Supawadee; Zhu, Guo-Yuan; Jiang, Zhi-Hong; Bai, Li-Ping 2016 2016-09-30 None N PMC7126508 27425447.0 10.1016/j.fitote.2016.07.006 7tkvk0xd 0.372306 David_2013, Largo_2016, Abou-Hamdan_2018, Choudhury_2011 Li_X_2019, HUANG_2013, Almeida_2011, Xie_J_2018
419 Rieux_2020 Thiopurine Derivative-Induced Fpg/Nei DNA Glycosylase Inhibition: Structural, Dynamic and Functional Insights Rieux, Charlotte; Goffinont, Stéphane; Coste, Franck; Tber, Zahira; Cros, Julien; Roy, Vincent; Guérin, Martine; Gaudon, Virginie; Bourg, Stéphane; Biela, Artur; Aucagne, Vincent; Agrofoglio, Luigi; Garnier, Norbert; Castaing, Bertrand 2020 2020-03-17 COMM-USE N PMC7139703 32192183.0 10.3390/ijms21062058 97qegnlo 0.370392 Berkhout_2006, Blank_2017, Taschuk_2020, Naito_2007, Stork_2011 Grazioso_2012, Becker_2016
420 Liu_I_2013 Peptides Corresponding to the Predicted Heptad Repeat 2 Domain of the Feline Coronavirus Spike Protein Are Potent Inhibitors of Viral Infection Liu, I-Jung; Tsai, Wan-Ting; Hsieh, Li-En; Chueh, Ling-Ling 2013 2013-12-03 COMM-USE N PMC3849439 24312629.0 10.1371/journal.pone.0082081 pslcp5ob 0.370082 Tallmadge_2008, Naito_2007, Jiang_2006, Ban_J_2018, Li_C_2013 McDonagh_2011, Valle-Casuso_2020, Jiang_2017, Hsieh_2010
421 Pandey_2018 Broad-spectrum neutralization of avian influenza viruses by sialylated human milk oligosaccharides: in vivo assessment of 3′-sialyllactose against H9N2 in chickens Pandey, Ramesh Prasad; Kim, Dae Hee; Woo, Jinsuk; Song, Jaeyoung; Jang, Sang Ho; Kim, Joon Bae; Cheong, Kwang Myun; Oh, Jin Sik; Sohng, Jae Kyung 2018 2018-02-07 COMM-USE N PMC5803236 29416087.0 10.1038/s41598-018-20955-4 53lnboez 0.369394 Lu_P_2016, Yasui_2016, Tallmadge_2008, van_Riel_2007, Schwartz_2007 Jiang_2017, Li_W_2013, Lin_S_2013, Elshabrawy_2012
422 Chien_2020 Nucleotide Analogues as Inhibitors of SARS-CoV-2 Polymerase Minchen Chien; Thomas K. Anderson; Steffen Jockusch; Chuanjuan Tao; Shiv Kumar; Xiaoxu Li; James J. Russo; Robert Kirchdoerfer; Jingyue Ju 2020 2020-03-20 BioRxiv Y 10.1101/2020.03.18.997585 8prn86g6 0.368317 Stork_2011, Meyerson_2017, Kang_2009, Pong_2011, Yasuda-Inoue_2013 Ju_J_2020, Yamamoto_2004, Veiga_2006, Zhou_2011
423 Wang_2017 Discovery of unsymmetrical aromatic disulfides as novel inhibitors of SARS-CoV main protease: Chemical synthesis, biological evaluation, molecular docking and 3D-QSAR study Wang, Li; Bao, Bo-Bo; Song, Guo-Qing; Chen, Cheng; Zhang, Xu-Meng; Lu, Wei; Wang, Zefang; Cai, Yan; Li, Shuang; Fu, Sheng; Song, Fu-Hang; Yang, Haitao; Wang, Jian-Guo 2017 2017-09-08 PMC N PMC7115414 28624700.0 10.1016/j.ejmech.2017.05.045 mxnx4mmu 0.368298 Naito_2007, Ekins_2014, Park_2012, Zhang_2004, Berkhout_2006 Niu_C_2008, Liu_W_2014, Zhu_L_2011, Thanigaimalai_2013
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425 Picard-Jean_2013 The Immunosuppressive Agent Mizoribine Monophosphate Is an Inhibitor of the Human RNA Capping Enzyme Picard-Jean, Frédéric; Bougie, Isabelle; Shuto, Satoshi; Bisaillon, Martin 2013 2013-01-17 COMM-USE N PMC3547949 23349942.0 10.1371/journal.pone.0054621 dr2uow4m 0.367339 Blank_2017, Ivanova_2015, Stork_2011, Kang_2009, Yasuda-Inoue_2013 Tremblay-Létourneau_2011, Sticher_2020, Wilde_2019
426 Ma_C_2020 Boceprevir, GC-376, and calpain inhibitors II, XII inhibit SARS-CoV-2 viral replication by targeting the viral main protease Chunlong Ma; Brett Hurst; Yanmei Hu; Tommy Szeto; Bart Tarbet; Jun Wang 2020 2020-04-20 BioRxiv Y 10.1101/2020.04.20.051581 047xpt2c 0.366996 Naito_2007, Berkhout_2006, Anderson_2009, Li_C_2017, Kumar_2016
427 Wang_2010 Molecular simulation study of the binding mechanism of [α-PTi(2)W(10)O(40)](7−) for its promising broad-spectrum inhibitory activity to FluV-A neuraminidase Wang, JianPing; Hu, DongHua; Su, ZhongMin 2010 2010-08-14 PMC N PMC7089260 10.1007/s11434-010-3271-8 5wieasp8 0.366886 Callison_1999, Ivarsson_2012, Smith_2003, Chan_2016, UNKNOWN_1987 Pahonțu_2015, Grazioso_2012, Yang_2010, Zhang_2017
428 Sticher_2020 Analysis of the Potential for N(4)-Hydroxycytidine To Inhibit Mitochondrial Replication and Function Sticher, Zachary M.; Lu, Gaofei; Mitchell, Deborah G.; Marlow, Joshua; Moellering, Levi; Bluemling, Gregory R.; Guthrie, David B.; Natchus, Michael G.; Painter, George R.; Kolykhalov, Alexander A. 2020 2020-01-27 None N PMC6985706 31767721.0 10.1128/aac.01719-19 hkfkugzn 0.365940 Volmer_2010, Stork_2011, Brunner_2010, Masante_2015, Kang_2009 Sun_D_2016, Sidhu_1996
429 Puranik_2019 Evaluation of the Antiviral Potential of Halogenated Dihydrorugosaflavonoids and Molecular Modeling with nsP3 Protein of Chikungunya Virus (CHIKV) Puranik, Ninad\nV.; Rani, Ruchi; Singh, Vedita Anand; Tomar, Shailly; Puntambekar, Hemalata M.; Srivastava, Pratibha 2019 2019-11-18 PMC N PMC6893968 31815237.0 10.1021/acsomega.9b02900 5kffoext 0.365940 Naito_2007, Kang_2009, Stork_2011, Meyerson_2017, Volmer_2010 Lee_C_2019, Zhao_2016, Nie_L_2020, Ren_Z_2010
430 Ehmke_2011 Potent and Selective Inhibition of Cysteine Proteases from Plasmodium falciparum and Trypanosoma brucei Ehmke, Veronika; Heindl, Cornelia; Rottmann, Matthias; Freymond, Céline; Schweizer, W. Bernd; Brun, Reto; Stich, August; Schirmeister, Tanja; Diederich, François 2011 2011-02-07 None N PMC7162187 21275051.0 10.1002/cmdc.201000449 g14kt2dv 0.364531 Choudhury_2011, Abou-Hamdan_2018, David_2013, Largo_2016
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433 Kwon_2015 In vitro anti-reovirus activity of kuraridin isolated from Sophora flavescens against viral replication and hemagglutination Kwon, Hyung-Jun; Jeong, Jae-Ho; Lee, Seung Woong; Ryu, Young Bae; Jeong, Hyung Jae; Jung, Kyungsook; Lim, Jae Sung; Cho, Kyoung-Oh; Lee, Woo Song; Rho, Mun-Chual; Park, Su-Jin 2015 2015-08-31 PMC N 26076959.0 10.1016/j.jphs.2015.04.007 6uuitwip 0.361383 Meyerson_2017, Tallmadge_2008, Kang_2009, Ban_J_2018, Volmer_2010
434 Tanaka_2016 Cellular peptidyl-prolyl cis/trans isomerase Pin1 facilitates replication of feline coronavirus Tanaka, Yoshikazu; Amano, Arisa; Morisaki, Masateru; Sato, Yuka; Sasaki, Takashi 2016 2016-02-29 PMC N PMC7113879 26675666.0 10.1016/j.antiviral.2015.11.013 4fnvb9i0 0.361228 Ban_J_2018, Kumar_2016, Yasuda-Inoue_2013, Greene_2012, Liu_X_2013 Zhou_2012, Wilde_2019
435 Shigeta_2006 Anti-RNA virus activity of polyoxometalates Shigeta, Shiro; Mori, Shuichi; Yamase, Toshihiro; Yamamoto, Norio; Yamamoto, Naoki 2006 2006-06-30 PMC N PMC7118841 16737794.0 10.1016/j.biopha.2006.03.009 siyyve9e 0.360712 Lu_P_2016, Tallmadge_2008, Yasui_2016, De_Clercq_2005, Crowe_2014 Valle-Casuso_2020, Zhou_2012, Furuta_2009
436 Glatthaar-Saalmüller_2015 Antiviral activity of an aqueous extract derived from Aloe arborescens Mill. against a broad panel of viruses causing infections of the upper respiratory tract Glatthaar-Saalmüller, B.; Fal, A.M.; Schönknecht, K.; Conrad, F.; Sievers, H.; Saalmüller, A. 2015 2015-09-15 PMC N PMC7127631 26321740.0 10.1016/j.phymed.2015.06.006 tsh7b5r6 0.359996 Tallmadge_2008, Lu_P_2016, Yasui_2016, Rice_1992, Ryu_W_2017 Chathuranga_2019, Ren_Z_2010, Lee_C_2019, Yang_2014
437 Keyaerts_2004 Inhibition of SARS-coronavirus infection in vitro by S-nitroso-N-acetylpenicillamine, a nitric oxide donor compound Keyaerts, Els; Vijgen, Leen; Chen, Luni; Maes, Piet; Hedenstierna, Göran; Van Ranst, Marc 2004 2004-07-31 PMC N PMC7128975 15234326.0 10.1016/j.ijid.2004.04.012 78xva8a0 0.359992 Tallmadge_2008, Yasui_2016, Naito_2007, Xu_L_2014, Shen_2005 Barnard_2006, Yamamoto_2004, Sidhu_1996, Åkerström_2009
438 Jin_L_2004 Inhibition of alcohol dehydrogenase by bismuth Jin, Lan; Szeto, Ka-Yee; Zhang, Li; Du, Weihong; Sun, Hongzhe 2004 2004-08-31 PMC N PMC7126473 15271509.0 10.1016/j.jinorgbio.2004.03.016 07bl9d00 0.359989 Smith_2003, Ivarsson_2012, Tosoni_2015, Chan_2016, Blank_2017 Grazioso_2012, Wang_2018, Kim_J_2019, Sidhu_1996
439 Shi_Y_2018 Identification of two antiviral inhibitors targeting 3C-like serine/3C-like protease of porcine reproductive and respiratory syndrome virus and porcine epidemic diarrhea virus Shi, Yuejun; Lei, Yingying; Ye, Gang; Sun, Limeng; Fang, Liurong; Xiao, Shaobo; Fu, Zhen F.; Yin, Ping; Song, Yunfeng; Peng, Guiqing 2018 2018-01-31 PMC N PMC7117380 29291994.0 10.1016/j.vetmic.2017.11.031 ikjjjn4s 0.358736 Tallmadge_2008, Yasui_2016, Ryu_W_2017, van_Riel_2007, Kamau_2019 Jiang_2017, Ma_Z_2013, Hu_H_2019
440 Wang_2019 Long-Acting HIV-1 Fusion Inhibitory Peptides and their Mechanisms of Action Wang, Chen; Cheng, Shuihong; Zhang, Yuanyuan; Ding, Yibo; Chong, Huihui; Xing, Hui; Jiang, Shibo; Li, Xuebing; Ma, Liying 2019 2019-09-02 COMM-USE N PMC6784077 31480738.0 10.3390/v11090811 cb0xe1sw 0.356890 Naito_2007, Jiang_2006, Yang_2010, Brake_2008, Meng_2008 Zhu_X_2015, Chen_2012, Wang_2014
441 Sakurai_2018 Novel amodiaquine derivatives potently inhibit Ebola virus infection Sakurai, Yasuteru; Sakakibara, Norikazu; Toyama, Masaaki; Baba, Masanori; Davey, Robert A. 2018 2018-12-31 PMC N 30395872.0 10.1016/j.antiviral.2018.10.025 z0utlk4p 0.356859 Naito_2007, Berkhout_2006, Tripp_2014, Falzarano_2015, Shaw_2011
442 Qing_2014 Cyclophilin A Associates with Enterovirus-71 Virus Capsid and Plays an Essential Role in Viral Infection as an Uncoating Regulator Qing, Jie; Wang, Yaxin; Sun, Yuna; Huang, Jiaoyan; Yan, Wenzhong; Wang, Jinglan; Su, Dan; Ni, Cheng; Li, Jian; Rao, Zihe; Liu, Lei; Lou, Zhiyong 2014 2014-10-02 COMM-USE N PMC4183573 25275585.0 10.1371/journal.ppat.1004422 9th2jiq6 0.356768 Meyerson_2017, Trobaugh_2017, Ban_J_2018, Li_C_2014, Kumar_2016 Yan_J_2020, Zhou_2012, Sun_D_2016
443 Dzhekieva_2013 Inhibition of DD-Peptidases by a Specific Trifluoroketone: Crystal Structure of a Complex with the Actinomadura R39 DD-Peptidase() Dzhekieva, Liudmila; Adediran, S. A.; Herman, Raphael; Kerff, Frédéric; Duez, Colette; Charlier, Paulette; Sauvage, Eric; Pratt, R.F. 2013 2013-03-13 PMC N PMC3731424 23484909.0 10.1021/bi400048s yn7x1gdq 0.356142 Schlieker_2007, Smith_2003, Cleary_2015, Ho_S_2009, Ivarsson_2012 Grazioso_2012, Yin_J_2007, Becker_2016, Lee_T_2005
444 Prior_2013 Design, synthesis, and bioevaluation of viral 3C and 3C-like protease inhibitors Prior, Allan M.; Kim, Yunjeong; Weerasekara, Sahani; Moroze, Meghan; Alliston, Kevin R.; Uy, Roxanne Adeline Z.; Groutas, William C.; Chang, Kyeong-Ok; Hua, Duy H. 2013 2013-12-01 None N PMC3863581 24125888.0 10.1016/j.bmcl.2013.09.070 ly8ibnju 0.355463 Tallmadge_2008, Crowe_2014, Meyerson_2017, Ryu_W_2017, Lu_P_2016 Grazioso_2012, Im_I_2009, Cho_A_2012, Dude_2008
445 Bryndal_2019 Crystal structure, vibrational and optic properties of 2-N-methylamino-3-methylpyridine N-oxide – Its X-ray and spectroscopic studies as well as DFT quantum chemical calculations Bryndal, I.; Lorenc, J.; Macalik, L.; Michalski, J.; Sąsiadek, W.; Lis, T.; Hanuza, J. 2019 2019-11-05 PMC N 10.1016/j.molstruc.2019.05.064 1l4cwxnn 0.354569 Puglisi_1990, Belova_2018, Karpińska_2013, Langosch_2011
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448 Acker_2011 Mechanism for Noncompetitive Inhibition by Novel GluN2C/D N-Methyl-d-aspartate Receptor Subunit-Selective Modulators Acker, Timothy M.; Yuan, Hongjie; Hansen, Kasper B.; Vance, Katie M.; Ogden, Kevin K.; Jensen, Henrik S.; Burger, Pieter B.; Mullasseril, Praseeda; Snyder, James P.; Liotta, Dennis C.; Traynelis, Stephen F. 2011 2011-08-01 PMC N PMC3198917 21807990.0 10.1124/mol.111.073239 7tkbh9k3 0.353319 Ivarsson_2012, Smith_2003, UNKNOWN_1987, Chang_2000 Grazioso_2012, Manta_2009, Głowacka_2015, Tsoukala_2010
449 Taherkhani_2013 In Vitro Anti-rotaviral Activity of Achillea kellalensis Taherkhani, Reza; Farshadpour, Fatemeh; Makvandi, Manoochehr 2013 2013-07-17 COMM-USE N PMC3941895 24624203.0 qebswt0o 0.353147 Volmer_2010, Naito_2007, Brake_2008, González-González_2008, Berkhout_2006 Klein_2008, Wu_H_2016, Chen_2019, Liu_Z_2015
450 Shin_2018 Gemcitabine and Nucleos(t)ide Synthesis Inhibitors Are Broad-Spectrum Antiviral Drugs that Activate Innate Immunity Shin, Hye Jin; Kim, Chonsaeng; Cho, Sungchan 2018 2018-04-20 COMM-USE N PMC5923505 29677162.0 10.3390/v10040211 g9a72xf6 0.352711 Berkhout_2006, Rajsbaum_2013, Shi_J_2012, Schoggins_2011 Chen_2019, Zhu_X_2015, Lee_K_2017
451 Li_Q_2012 An efficient three-component, one-pot synthesis of 2-alkylthio-4-amino-5-cyano-6-aryl(alkyl)pyrimidines in water Li, Qiao-Yan; Ge, Ze-Mei; Cheng, Tie-Ming; Li, Run-Tao 2012 2012-06-28 PMC N PMC7088670 22740103.0 10.1007/s11030-012-9376-z 02g592st 0.352565 Largo_2016, David_2013, Choudhury_2011, Abou-Hamdan_2018, Niu_P_2016 Tsoukala_2010, Pomeisl_2019, Paramonova_2017, Głowacka_2015
452 Sun_J_2011 Inhibition of hepatitis C virus replication by Monascus pigment derivatives that interfere with viral RNA polymerase activity and the mevalonate biosynthesis pathway Sun, Ji-Min; Kim, Seong-Jun; Kim, Geon-Woo; Rhee, Jin-Kyu; Kim, Nam Doo; Jung, Heeyong; Jeun, Jungae; Lee, Seung-Hoon; Han, Seung Hyun; Shin, Chul Soo; Oh, Jong-Won 2011 2011-11-09 PMC N PMC7109977 22076990.0 10.1093/jac/dkr432 8hiymqyb 0.351419 Kang_2009, Meyerson_2017, Stork_2011, Pong_2011, Naito_2007 Obeid_2011, Valle-Casuso_2020, Zhou_2012, Mingorance_2018
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456 Hung_2010 Inhibition of enterovirus 71 replication and the viral 3D polymerase by aurintricarboxylic acid Hung, Hui-Chen; Chen, Tzu-Chun; Fang, Ming-Yu; Yen, Kuei-Jung; Shih, Shin-Ru; Hsu, John T.-A.; Tseng, Ching-Ping 2010 2010-01-20 PMC N PMC7110181 20089540.0 10.1093/jac/dkp502 xj64bpgs 0.348529 Meyerson_2017, Kang_2009, Stork_2011, Li_C_2013, Tallmadge_2008 Yao_C_2018, van_der_Linden_2014, Sun_D_2016, Sidhu_1996
457 Nevers_2018 Characterization of the Anti-Hepatitis C Virus Activity of New Nonpeptidic Small-Molecule Cyclophilin Inhibitors with the Potential for Broad Anti-Flaviviridae Activity Nevers, Quentin; Ruiz, Isaac; Ahnou, Nazim; Donati, Flora; Brillet, Rozenn; Softic, Laurent; Chazal, Maxime; Jouvenet, Nolwenn; Fourati, Slim; Baudesson, Camille; Bruscella, Patrice; Gelin, Muriel; Guichou, Jean-François; Pawlotsky, Jean-Michel; Ahmed-Belkacem, Abdelhakim 2018 2018-06-26 None N PMC6021681 29760125.0 10.1128/aac.00126-18 35k4065e 0.347789 Kang_2009, Berkhout_2006, Kumar_2016, Naito_2007, Haasnoot_2010 Zhu_X_2015, Ahmed-Belkacem_2016
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477 Regev-Shoshani_2013 Gaseous nitric oxide reduces influenza infectivity in vitro Regev-Shoshani, Gilly; Vimalanathan, Selvarani; McMullin, Bevin; Road, Jeremy; Av-Gay, Yossef; Miller, Chris 2013 2013-05-31 PMC N PMC7110511 23562771.0 10.1016/j.niox.2013.03.007 4bqr8bvg 0.331371 Yasui_2016, Tallmadge_2008, Volmer_2010, Schwartz_2007, Berkhout_2006 Ishag_2012, Sidhu_1996, Åkerström_2009, Song_2018
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479 Patil_2015 Phosphonooxymethyl Prodrug of Triptolide: Synthesis, Physicochemical Characterization, and Efficacy in Human Colon Adenocarcinoma and Ovarian Cancer Xenografts Patil, Satish; Lis, Lev G.; Schumacher, Robert\nJ.; Norris, Beverly J.; Morgan, Monique L.; Cuellar, Rebecca A. D.; Blazar, Bruce R.; Suryanarayanan, Raj; Gurvich, Vadim J.; Georg, Gunda I. 2015 2015-11-24 PMC N PMC4678411 26596892.0 10.1021/acs.jmedchem.5b01329 zhf8jdcl 0.329966 David_2013, Largo_2016, Abou-Hamdan_2018, Choudhury_2011 Mehellou_2010, Chen_2019, McGuigan_2013, Grazioso_2012
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481 von_Brunn_2015 Genetic deficiency and polymorphisms of cyclophilin A reveal its essential role for Human Coronavirus 229E replication von Brunn, Albrecht; Ciesek, Sandra; von Brunn, Brigitte; Carbajo-Lozoya, Javier 2015 2015-10-31 PMC N PMC7102849 26318518.0 10.1016/j.coviro.2015.08.004 8oyonsoj 0.329847 Rice_1992, Meyerson_2017, Pong_2011, Stork_2011, den_Boon_2010 Tanaka_2013, Zhou_2012, Wilde_2019
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484 Marbawati_2015 Effects of Curcumin and Pentagamavunon-0 Against Dengue-2 Virus Infection in Vero Cells; an in Vitro Study Marbawati, Dewi; Umniyati, Sitti Rahmah 2015 2015-12-31 PMC N 10.1016/j.proenv.2015.01.033 zbxp2pvd 0.328701 Volmer_2010, Oosterhoff_2015, Farias_2013, Brake_2008, Li_L_2013 Zhong_2009, Yao_C_2018, Yang_2014, Klein_2008
485 Hartman_2016 Preclinical evaluation of a mercaptobenzamide and its prodrug for NCp7-targeted inhibition of human immunodeficiency virus Hartman, T.L.; Yang, L.; Helfrick, A.N.; Hassink, M.; Shank, N.I.; George Rosenker, K.; Scerba, M.T.; Saha, M.; Hughes, E.; Wang, A.Q.; Xu, X.; Gupta, P.; Buckheit, R.W.; Appella, D.H. 2016 2016-10-31 PMC N PMC7113734 27568924.0 10.1016/j.antiviral.2016.08.022 45glufnh 0.324666 Naito_2007, Berkhout_2006, Compton_2014, Rice_1992, Liu_Y_2008 Zhu_X_2015, Zhou_2012, Valle-Casuso_2020
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487 Preobrazhenskaya_2006 Polycyclic peptide and glycopeptide antibiotics and their derivatives as inhibitors of HIV entry Preobrazhenskaya, Maria N.; Olsufyeva, Eugenia N. 2006 2006-09-30 PMC N PMC7114112 16720053.0 10.1016/j.antiviral.2006.04.008 jvqvcz5j 0.322258 Naito_2007, Sousa_2016, Zakaryan_2017, Fernández‐Oliva_2019 Lee_C_2019, Zhu_X_2015, Lin_J_2008, Szűcs_2018
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489 Keyaerts_2007 Plant lectins are potent inhibitors of coronaviruses by interfering with two targets in the viral replication cycle Keyaerts, Els; Vijgen, Leen; Pannecouque, Christophe; Van Damme, Els; Peumans, Willy; Egberink, Herman; Balzarini, Jan; Van Ranst, Marc 2007 2007-09-30 PMC N PMC7114093 17428553.0 10.1016/j.antiviral.2007.03.003 6qmckoo8 0.320888 Volmer_2010, Yasui_2016, Tallmadge_2008, Rice_1992, Auewarakul_2005 Lee_C_2019, van_der_Meer_2007, van_der_Meer_2007, Niemeyer_2018
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491 Wu_K_2009 Preparation and characterization of polyoxometalate-modified poly(vinyl alcohol)/polyethyleneimine hybrids as a chemical and biological self-detoxifying material Wu, K.H.; Yu, P.Y.; Yang, C.C.; Wang, G.P.; Chao, C.M. 2009 2009-09-30 PMC N PMC7112374 10.1016/j.polymdegradstab.2009.05.009 e17rjfk4 0.320363 Shavandi_2019, Jiang_2011, Lee_J_2016, Qi_Z_2018, Ruiz-Herrero_2015 Darvishi_2015, Li_N_2017, He_W_2008
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493 Chen_2005 Inhibition of SARS-CoV 3C-like Protease Activity by Theaflavin-3,3′-digallate (TF3) Chen, Chia-Nan; Lin, Coney P. C.; Huang, Kuo-Kuei; Chen, Wei-Cheng; Hsieh, Hsin-Pang; Liang, Po-Huang; Hsu, John T.-A. 2005 2005-04-07 PMC N PMC1142193 15937562.0 10.1093/ecam/neh081 0svscbpu 0.318110 Yang_2010, Friedman_2006, Cai_Y_2004, Xu_X_2016 Grazioso_2012, Lee_C_2009, Lin_C_2004
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498 Botta_2015 Carbon nanotubes supported tyrosinase in the synthesis of lipophilic hydroxytyrosol and dihydrocaffeoyl catechols with antiviral activity against DNA and RNA viruses Botta, Giorgia; Bizzarri, Bruno Mattia; Garozzo, Adriana; Timpanaro, Rossella; Bisignano, Benedetta; Amatore, Donatella; Palamara, Anna Teresa; Nencioni, Lucia; Saladino, Raffaele 2015 2015-09-01 PMC N PMC7125559 26260341.0 10.1016/j.bmc.2015.07.061 8oes5g6k 0.313685 Davaro_2013, Tallmadge_2008, Garcia–Moliner_2013, Crowe_2014 Grazioso_2012, Cheng_2014, Ren_Z_2010, Spisakova_2009
499 Kasthuri_2011 Synthesis of (R)- and (S)-β-hydroxyphosphonate acyclonucleosides: structural analogues of Adefovir (PMEA) Kasthuri, Mahesh; Chaloin, Laurent; Périgaud, Christian; Peyrottes, Suzanne 2011 2011-07-31 PMC N 10.1016/j.tetasy.2011.08.010 zjq464w7 0.313620 Dai_Q_2012, Qi_Z_2018, Chang_2011, Saw_A_2019, Liao_2006 Kumarapperuma_2007, Chopade_2016, Paramonova_2017, Cho_A_2012
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501 Dai_W_2020 Structure-Based Design, Synthesis and Biological Evaluation of Peptidomimetic Aldehydes as a Novel Series of Antiviral Drug Candidates Targeting the SARS-CoV-2 Main Protease Wenhao Dai; Bing Zhang; Xia-Ming Jiang; Haixia Su; Jian Li; Yao Zhao; Xiong Xie; Zhenming Jin; Jingjing Peng; Fengjiang Liu; Chunpu Li; You Li; Fang Bai; Haofeng Wang; Xi Cheng; Xiaobo Cen; Shulei Hu; Xiuna Yang; Jiang Wang; Xiang Liu; Gengfu Xiao; Hualiang Jiang; Zihe Rao; Leike Zhang; Yechun Xu; Haitao Yang; Hong Liu 2020 2020-03-28 BioRxiv Y 10.1101/2020.03.25.996348 b4joa5tx 0.312820 Naito_2007, Berkhout_2006, Haasnoot_2010, Volmer_2010, Yang_2010 Konno_2013, Thanigaimalai_2013, Thanigaimalai_2013, Niu_C_2008
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507 Kim_B_2015 Benserazide, the first allosteric inhibitor of Coxsackievirus B3 3C protease Kim, Bo-Kyoung; Cho, Joong-Heui; Jeong, Pyeonghwa; Lee, Youngjin; Lim, Jia Jia; Park, Kyoung Ryoung; Eom, Soo Hyun; Kim, Yong-Chul 2015 2015-07-08 PMC N PMC7094222 26022398.0 10.1016/j.febslet.2015.05.027 4szi4vyd 0.309081 Pong_2011, Choudhury_2017, Kang_2009, Li_C_2017, Naito_2007 Grazioso_2012, Lee_H_2013, Zhong_2009, Zhu_X_2015
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511 Torres_2013 Role of the viral hemagglutinin in the anti-influenza virus activity of newly synthesized polycyclic amine compounds Torres, Eva; Duque, María D.; Vanderlinden, Evelien; Ma, Chunlong; Pinto, Lawrence H.; Camps, Pelayo; Froeyen, Mathy; Vázquez, Santiago; Naesens, Lieve 2013 2013-09-30 PMC N PMC7114147 23800838.0 10.1016/j.antiviral.2013.06.006 8ndct2xm 0.307221 Yasui_2016, Lu_P_2016, Tallmadge_2008, Wrammert_2011, van_Riel_2007 Grazioso_2012, Tonelli_2017, Hu_J_2017
512 Attioui_1994 Recognition ability and cytotoxicity of some oligosaccharidylsubstituted β-cyclodextrins Attioui, Fatima; Al-Omar, Anouar; Leray, Eric; Parrot-Lopez, Hélène; Finance, Chantal; Bonaly, Roger 1994 1994-12-31 PMC N PMC7131397 7606211.0 10.1016/s0248-4900(94)80018-9 vtctnqki 0.307139 Volmer_2010, Ivarsson_2012, Berkhout_2006, Wu_G_2005, Moon_2012 Cheng_2014, Grazioso_2012, Xie_J_2018, McDowell_1988
513 Zhou_2010 QSAR models for predicting cathepsin B inhibition by small molecules—Continuous and binary QSAR models to classify cathepsin B inhibition activities of small molecules Zhou, Zhigang; Wang, Yanli; Bryant, Stephen H. 2010 2010-06-30 None N PMC2873115 20194042.0 10.1016/j.jmgm.2010.01.009 bs17igjs 0.305801 Saw_A_2019, Chang_2011, Qi_Z_2018, Dai_Q_2012, Feng_2010 Wang_2006, Tian_2012, Theerawatanasirikul_2020, Lee_H_2014
514 Liu_J_2007 Treatment of lycorine on SCID mice model with human APL cells Liu, J.; Li, Y.; Tang, L.J.; Zhang, G.P.; Hu, W.X. 2007 2007-05-31 PMC N PMC7126558 17336028.0 10.1016/j.biopha.2007.01.003 nt11f2x8 0.305613 Schindler_1983, Yamaguchi_1991, Macnaughton_1980, Zhou_2006, UNKNOWN_1983 Klein_2008, Li_L_2012, Liu_J_2010, Yang_2016
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516 Jockusch_2020 Triphosphates of the Two Components in DESCOVY and TRUVADA are Inhibitors of the SARS-CoV-2 Polymerase Steffen Jockusch; Chuanjuan Tao; Xiaoxu Li; Thomas K. Anderson; Minchen Chien; Shiv Kumar; James J. Russo; Robert Kirchdoerfer; Jingyue Ju 2020 2020-04-05 BioRxiv Y 10.1101/2020.04.03.022939 awbcw3gq 0.304731 Naito_2007, Magden_2004, Stork_2011, Ryu_W_2017, Kang_2009 Niemeyer_2018, Barnard_2006, Valle-Casuso_2020, Ergonul_2007
517 Han_D_2006 Identification of critical determinants on ACE2 for SARS-CoV entry and development of a potent entry inhibitor Han, Dong P.; Penn-Nicholson, Adam; Cho, Michael W. 2006 2006-06-20 PMC Y PMC7111894 16510163.0 10.1016/j.virol.2006.01.029 v1mf5lhh 0.304267 Yang_2010, Ban_J_2018, Naito_2007, Li_C_2017, Tallmadge_2008 Haga_2010, Yuan_2004, Veiga_2006, Zhang_2009
518 Wu_C_2006 Stable Benzotriazole Esters as Mechanism-Based Inactivators of the Severe Acute Respiratory Syndrome 3CL Protease Wu, Chung-Yi; King, Ke-Yung; Kuo, Chih-Jung; Fang, Jim-Min; Wu, Ying-Ta; Ho, Ming-Yi; Liao, Chung-Lin; Shie, Jiun-Jie; Liang, Po-Huang; Wong, Chi-Huey 2006 2006-03-31 None N PMC7111201 16638531.0 10.1016/j.chembiol.2005.12.008 bfrozfvg 0.303094 Naito_2007, Volmer_2010, Berkhout_2006, Callison_1999, Hu_T_2009 Grazioso_2012, Piras_2019, Verschueren_2008, Kuo_C_2008
519 Dakkouri_2013 A theoretical investigation of the structure of 2-nitropyridine-N-oxide and the dependency of the NO(2) torsional motion on the applied wavefunction and basis set Dakkouri, Marwan; Typke, Volker 2013 2013-01-23 PMC N PMC7088725 10.1007/s11224-012-0198-5 c59s8kji 0.302863 Polverino_2017, Liao_2006, Qi_Z_2018, Karpińska_2013, Cheng_2010 Belova_2018, Jezierska-Mazzarello_2011, Grazioso_2012, Tsoukala_2010
520 Yao_Q_2010 A new chitin-binding lectin from rhizome of Setcreasea purpurea with antifungal, antiviral and apoptosis-inducing activities Yao, Qing; Wu, Chuan-fang; Luo, Ping; Xiang, Xiao-cong; Liu, Jun-jie; Mou, Lin; Bao, Jin-ku 2010 2010-09-30 PMC N 10.1016/j.procbio.2010.05.026 b26ldlrb 0.302411 Yang_2010, Ban_J_2018, Kang_2009, Landeo-Ríos_2016, Li_C_2017 Xie_J_2018, Gondim_2019, Naik_2017
521 Hu_H_2019 Antiviral activity of Piscidin 1 against pseudorabies virus both in vitro and in vivo Hu, Han; Guo, Nan; Chen, Shuhua; Guo, Xiaozhen; Liu, Xiaoli; Ye, Shiyi; Chai, Qingqing; Wang, Yang; Liu, Binlei; He, Qigai 2019 2019-07-31 COMM-USE N PMC6670175 31366370.0 10.1186/s12985-019-1199-4 de1lmzl1 0.302218 Tallmadge_2008, Yasui_2016, Naito_2007, Compton_2014, Jiang_2006 Zhou_2012, Zhong_2009, Yao_C_2018, Wu_H_2016
522 Hu_D_2007 Studies on the interactions of Ti-containing polyoxometalates (POMs) with SARS-CoV 3CLpro by molecular modeling Hu, Donghua; Shao, Chen; Guan, Wei; Su, Zhongmin; Sun, Jiazhong 2007 2007-01-31 None N PMC7112571 17049610.0 10.1016/j.jinorgbio.2006.08.013 azosg1tt 0.301452 Pong_2011, Naito_2007, Chan_2016, Ivarsson_2012, Stork_2011 Grazioso_2012, Niu_C_2008, Thanigaimalai_2013
523 Jalali-Heravi_2009 Shuffling multivariate adaptive regression splines and adaptive neuro-fuzzy inference system as tools for QSAR study of SARS inhibitors Jalali-Heravi, M.; Asadollahi-Baboli, M.; Mani-Varnosfaderani, A. 2009 2009-12-05 PMC N PMC7126869 19665859.0 10.1016/j.jpba.2009.07.009 bf5rct4q 0.300882 Saw_A_2019, Liao_2006, Dai_Q_2012, Höhle_2007, Qi_Z_2018 Zhou_2010, Wang_2018, Mukherjee_2011
524 Kumar_2016 Identification, synthesis and evaluation of SARS-CoV and MERS-CoV 3C-like protease inhibitors Kumar, Vathan; Tan, Kian-Pin; Wang, Ying-Ming; Lin, Sheng-Wei; Liang, Po-Huang 2016 2016-07-01 PMC N PMC7079562 27240464.0 10.1016/j.bmc.2016.05.013 s9wb9275 0.300437 Ban_J_2018, Cheun-Arom_2015, Vui_D_2014, Li_C_2013, Wang_2014 Rut_W_2020, Adhikari_2017, Liu_W_2014
525 Keyaerts_2004 In vitro inhibition of severe acute respiratory syndrome coronavirus by chloroquine Keyaerts, Els; Vijgen, Leen; Maes, Piet; Neyts, Johan; Ranst, Marc Van 2004 2004-10-08 PMC N PMC7092815 15351731.0 10.1016/j.bbrc.2004.08.085 5lzzobl3 0.300388 Falzarano_2015, Ooi_E_2006, Naito_2007, Wang_2016 Yamamoto_2004, Wu_H_2016, Devaux_2020
526 Chung_2010 HTS-Driven Discovery of New Chemotypes with West Nile Virus Inhibitory Activity Chung, Dong Hoon; Jonsson, Colleen B.; Maddox, Clinton; McKellip, Sara N.; Moore, Blake. P.; Heil, Marintha; White, E. Lucile; Ananthan, Subramaniam; Li, Qianjun; Feng, Shuang; Rasmussen, Lynn 2010 2010-03-12 COMM-USE N PMC4839297 20336008.0 10.3390/molecules15031690 wybmer7o 0.300318 Naito_2007, Brake_2008, Armesto_2007, Liu_Y_2008, Keep_2015 Lee_C_2019, Valle-Casuso_2020