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Abstracts with Biological Entities (English) - 75 Topics / Sub-Topic Model 55

Topic 1 Topic 2 Topic 3 Topic 4 Topic 5 Topic 6 Topic 7 Topic 8 Topic 9 Topic 10 Topic 11 Topic 12 Topic 13 Topic 14 Topic 15
1 virus sars-cov binding dubs ISG15 dimer PRRSV macro nsp10 cleavage M1 = 3cpro chapter cathepsin
2 activity respiratory site ubiquitin DUB m(pro proteinase macro domain mtase furin peptidases crystals 3C chapters cathepsin l
3 replication syndrome active site enzymes ub dimerization nsp4 toxin nsp16 trypsin cathepsins nsp15 EV71 subject nipah
4 viral severe active cellular plpro pl(pro nsp11 bacterial methylation substrate aminopeptidases Å HAV edition mnsp15
5 protease acute structure modification deubiquitinating monomer cleavage clan cap position aminopeptidase space HEV chemistry cscatl
6 amino coronavirus crystal probes interferon dynamics predicted FAN1 RNA cleavage site USP2 asymmetric ‘ sections s-crystallin
7 mutations SARS catalytic review innate MD IBV nuclease nsp14 gln USP14 unit DHAV biological aspects cathepsin h
8 nsp2 3clpro enzyme adp-ribosylation ubiquitin extra reproductive endou methyltransferase positions serine space group x-domain preparation cscatd
9 RNA inhibitors structures proteins immune dimeric MHV superfamily mrna P3 enhance parameters 2A cleave proteins catalytic site
10 in vitro protease complex processes isgylation catalytic machinery 3c-like proteinase domains polymerase peptide tissue resolution dhav 3c protease third edition WT
11 vitro 3cl(pro pocket DNA ubiquitin-like simulations 1a bacteria SAM cov‐hku1 hemoglobin unit-cell + handbook antigen
12 CHIKV mers-cov substrate functions OTU extra domain MHV-A59 iga1 nsp8 nia TEB4 asymmetric unit ORF1 distinguishing trme
13 mutant compounds mechanism discuss responses molecular dynamics deletion proteases rdrp ser neurodegenerative unit-cell parameters RAP80 aims tap
14 amino acids assay interactions macrodomain response analytical ORF systems nsp12 P2 m1 aminopeptidases crystallized transcriptional activity reference gsp
15 enzymatic drug structural recent signaling ACE2 respiratory syndrome virus identity methyltransferases P4 families crystallization 3AB history P102
16 protein design reaction including chains interface p28 newly nsp7 cleaved inhibitors diffracted hev-protease keywords gspa
17 polyprotein acute respiratory syndrome crystal structures protein IFN ultracentrifugation porcine classification n7-guanine P5 family belonged hepatitis peptidase feline
18 residues main crystal structure E3 infection protomer sites macro domains capping vpg-pro cancer ° transcriptional organized ctfs
19 proteins inhibitory bound ligases USP18 dimer interface 3clpro rv0888 helicase ZT proteases β 3c protease structural chemistry trifluoroketone
20 mutants development bond target species loop nsp1α eukaryotes replication/transcription pro degradation Å. FMDV 800 APP
21 acids inhibitor model cellular processes MERS machinery arterivirus eukaryotic rlmm P1 UPS group enterovirus work CHES
22 viruses target report regulation viral infection form nsps proteins rna-cap arg fatty α cys172 describing SCF-I2
23 mutation 3CL group marylation polyub mers-cov pl(pro infectious bronchitis virus iga1 proteases surface p2 position APN γ luciferase peptides induces
24 acid attractive molecular UB tumor N214A bronchitis VEEV VI substrates proteasome belong picornaviral aspects L.
25 expression acute respiratory syndrome coronavirus pockets therapeutic interferon-stimulated dynamic processing flap 2′-O sites membrane escherichia octahydroisochromene comprehensive catfish
26 virus replication sars-cov 3clpro inhibitor important ifn-β catalytic ibv-infected adp-ribose 2′-o-methyltransferase tag cell content chaperone IV cpnanicd
27 viral replication mpro comparison deubiquitinating enzymes ovarian structure encoded PA N7 vpg result escherichia coli ORF3 enzymes protoplasts
28 motif coronaviruses observed TARG1 deubiquitinating activity R298A products nucleases mrnas S1′ members cloned ev71 3cpro features lens
29 papain-like coronaviral papain post-translational votus homodimer demonstrated comprises s-adenosyl-l-methionine iprot-sub natural 90 foot-and-mouth biological lepidoptera
30 domain antiviral fold pathways viral STI/A nonstructural CLN2 mtases sequence natural products diffraction azaglutamine cleave endoribonuclease-u
31 processing potent residues activity-based type m(pro)-c nucleotides β-hairpin 2'-O fusion prostate endoribonuclease β-ribbon NP cathepsin l.
32 function PEDV S2 regulates host catalysis 3c-like includes genetics site n-acyl Å(3 biosensor DPP USP12
33 wild-type activity recognition repair plps stable dipeptide human 2′O TV cysteine cathepsins da(−1 1-position dsrna niv
34 proteolytic activity kinetic hydrogen targets isg15s enzyme flanking common gtase specificities falcipain-2 molecules coxsackie specificity long-range
35 study cov cysteine chains nairovirus conformation arteriviridae nsp9 cap methylation fusion proteins falciparum coli chaperone activity proteinase fusion
36 dicer sars-cov mpro S1 parps 15 active 1a/1b TSHSV RTC hemagglutinin FAAH collected acidic domain proteolytic GST
37 processed peptide oxyanion human USP9X dissociation beaudette tas l protein ELP calpain uridylate acidic publisher catalyzes
38 analysis enzyme mpro ubiquitylation innate immune response covmpro ZF secretory tetrad tetrapeptide caspase-6 encodes alpha lassa %
39 non-structural proteins viral substrate binding PARP votu dimers mutagenesis positive-strand rna viruses domain RV cysteine diffract NEMO specific neu5ac
40 studies east catalytically E1 UL36-DUB active dimer cells prokaryotic conserved nia protease inhibition antiviral drug design picornain lassa virus subunits
41 essential 3c-like protease water dna damage gene SARS domains clan proteases complex P(1 aptamers NP-NTD kinetic analysis DAP protein
42 exhibited essential 2H mono-adp-ribosylation otus main mhv 3clpro CDI protein P2′ m1 family precipitant firefly pmdap acid
43 PRO IC50 warhead role USP15 fold nsp10a α(h exoribonuclease tags phenformin cubic benserazide exonucleases 13-fold
44 chikungunya optimization catalytic dyad substrates isopeptidase domain 290-kda widespread (+)RNA trans-activity subtilase BSA a.a ivs 2’-5
45 dicer protein inhibitory activity results biological deisgylating polyproteins ibv-infected cells hfan1 methylated P(2 plasma 120 rupintrivir dipeptidyl anion
46 virus-encoded peptidomimetic propose addition deisgylase residues zf domain SUKH structure kexin secreted hcov-hku1 picornavirus 850 melanin
47 VV antivirals cys145 parylation USP25 mutation PRRS phosphate region P(4 RING calculated protease silver 2.35-Å
48 catalytic study specificity UBL CCHFV allostery frame toxins sinefungin H5N1 falcipain-3 % yeast cells fly week
49 found therapeutics inhibitors biology deubiquitinating enzyme n-finger 1a/1b polyproteins DNA s-adenosylmethionine-dependent met FP-2 PEG v(max pestivirus exquisite
50 nsp1 resonance decahydroisoquinolin ZUFSP activity x‐ray swine conserved nsp10/nsp16 occupied lysosomal genome-encoded S10 494 blocker