Topic 09 -- Abstracts with Biological Entities (English) - 75 Topics / Sub-Topic Model 55 - 15 Topics

cite ad title authors publish year publish time dataset abstract mentions covid pmcid pubmed id doi cord uid topic weight Similarity scispacy Similarity specter
1 Ferron_2019 Identification of a Nidovirales Orf1a N7-guanine cap Methyltransferase signature-sequence as a genetic marker of large genome Tobaniviridae François Ferron; Humberto Julio Debat; Etienne Decroly; Bruno Canard 2019 2019-05-17 BioRxiv N 10.1101/639369 lnf2mj29 0.870963
2 Paesen_2015 X-ray structure and activities of an essential Mononegavirales L-protein domain Paesen, Guido C.; Collet, Axelle; Sallamand, Corinne; Debart, Françoise; Vasseur, Jean-Jacques; Canard, Bruno; Decroly, Etienne; Grimes, Jonathan M. 2015 2015-11-09 None N PMC4659945 26549102.0 10.1038/ncomms9749 1taxqkk2 0.773608 Kanitz_2019
3 te_Velthuis_2011 The SARS-coronavirus nsp7+nsp8 complex is a unique multimeric RNA polymerase capable of both de novo initiation and primer extension te Velthuis, Aartjan J.W.; van den Worm, Sjoerd H. E.; Snijder, Eric J. 2011 2011-10-29 NONCOMM N PMC3287201 22039154.0 10.1093/nar/gkr893 tx0lqgff 0.769413
4 Kusov_2015 A G-quadruplex-binding macrodomain within the “SARS-unique domain” is essential for the activity of the SARS-coronavirus replication–transcription complex Kusov, Yuri; Tan, Jinzhi; Alvarez, Enrique; Enjuanes, Luis; Hilgenfeld, Rolf 2015 2015-10-31 PMC N PMC4567502 26149721.0 10.1016/j.virol.2015.06.016 7lf2c2ra 0.743280 Paesen_2015
5 Ferron_2019 A N7-guanine RNA cap methyltransferase signature-sequence as a genetic marker of large genome, non-mammalian Tobaniviridae Ferron, François; Debat, Humberto J; Shannon, Ashleigh; Decroly, Etienne; Canard, Bruno 2019 2019-12-19 NONCOMM N PMC7107822 10.1093/nargab/lqz022 lmpxb359 0.730675 Ferron_2019
6 Martin_2018 The methyltransferase domain of the Sudan ebolavirus L protein specifically targets internal adenosines of RNA substrates, in addition to the cap structure Martin, Baptiste; Coutard, Bruno; Guez, Théo; Paesen, Guido C; Canard, Bruno; Debart, Françoise; Vasseur, Jean-Jacques; Grimes, Jonathan M; Decroly, Etienne 2018 2018-09-06 NONCOMM N PMC6125687 30192980.0 10.1093/nar/gky637 243u68j8 0.691388 Ferron_2019
7 Morin_2010 The N-Terminal Domain of the Arenavirus L Protein Is an RNA Endonuclease Essential in mRNA Transcription Morin, Benjamin; Coutard, Bruno; Lelke, Michaela; Ferron, François; Kerber, Romy; Jamal, Saïd; Frangeul, Antoine; Baronti, Cécile; Charrel, Rémi; de Lamballerie, Xavier; Vonrhein, Clemens; Lescar, Julien; Bricogne, Gérard; Günther, Stephan; Canard, Bruno 2010 2010-09-16 COMM-USE N PMC2940758 20862324.0 10.1371/journal.ppat.1001038 arwaj4yp 0.682729
8 Jin_X_2013 Characterization of the guanine-N7 methyltransferase activity of coronavirus nsp14 on nucleotide GTP Jin, Xu; Chen, Yu; Sun, Ying; Zeng, Cong; Wang, Yi; Tao, Jiali; Wu, Andong; Yu, Xiao; Zhang, Zhou; Tian, Jie; Guo, Deyin 2013 2013-09-30 PMC N PMC7114466 23702198.0 10.1016/j.virusres.2013.05.001 p628h7c8 0.669571
9 Lugari_2010 Molecular Mapping of the RNA Cap 2′-O-Methyltransferase Activation Interface between Severe Acute Respiratory Syndrome Coronavirus nsp10 and nsp16 Lugari, Adrien; Betzi, Stephane; Decroly, Etienne; Bonnaud, Emmanuel; Hermant, Aurélie; Guillemot, Jean-Claude; Debarnot, Claire; Borg, Jean-Paul; Bouvet, Mickaël; Canard, Bruno; Morelli, Xavier; Lécine, Patrick 2010 2010-08-10 PMC N PMC2963367 20699222.0 10.1074/jbc.m110.120014 h4cl022f 0.669128
10 Zhang_2010 Identification of aromatic amino acid residues in conserved region VI of the large polymerase of vesicular stomatitis virus is essential for both guanine-N-7 and ribose 2'-O methyltransferases Zhang, Xiaodong; Wei, Yongwei; Ma, Yuanmei; Hu, Songhua; Li, Jianrong 2010 2010-12-20 PMC N PMC7111938 20961592.0 10.1016/j.virol.2010.09.017 592oxd6m 0.663056 Rozanov_1995
11 Chen_2011 Biochemical and Structural Insights into the Mechanisms of SARS Coronavirus RNA Ribose 2′-O-Methylation by nsp16/nsp10 Protein Complex Chen, Yu; Su, Ceyang; Ke, Min; Jin, Xu; Xu, Lirong; Zhang, Zhou; Wu, Andong; Sun, Ying; Yang, Zhouning; Tien, Po; Ahola, Tero; Liang, Yi; Liu, Xinqi; Guo, Deyin 2011 2011-10-13 COMM-USE N PMC3192843 22022266.0 10.1371/journal.ppat.1002294 db7stx56 0.640771
12 Krichel_2019 Processing of the SARS-CoV pp1a/ab nsp7-10 region Boris Krichel; Sven Falke; Rolf Hilgenfeld; Lars Redecke; Charlotte Uetrecht 2019 2019-12-03 BioRxiv N 10.1101/860049 xfoqd6uk 0.623506 Krichel_2020, Yu_L_2017
13 Deng_2013 Structural basis for the regulatory function of a complex zinc-binding domain in a replicative arterivirus helicase resembling a nonsense-mediated mRNA decay helicase Deng, Zengqin; Lehmann, Kathleen C.; Li, Xiaorong; Feng, Chong; Wang, Guoqiang; Zhang, Qi; Qi, Xiaoxuan; Yu, Lin; Zhang, Xingliang; Feng, Wenhai; Wu, Wei; Gong, Peng; Tao, Ye; Posthuma, Clara C.; Snijder, Eric J.; Gorbalenya, Alexander E.; Chen, Zhongzhou 2013 2013-12-24 NONCOMM N PMC3950703 24369429.0 10.1093/nar/gkt1310 471zei5o 0.604949 Kanitz_2019
14 Krichel_2020 Processing of the SARS-CoV pp1a/ab nsp7–10 region Krichel, Boris; Falke, Sven; Hilgenfeld, Rolf; Redecke, Lars; Uetrecht, Charlotte 2020 2020-03-13 None N PMC7078746 32083638.0 10.1042/bcj20200029 6jdvrggp 0.595820 Krichel_2019, Yu_L_2017
15 Tan_Y_2018 Coronavirus infectious bronchitis virus non-structural proteins 8 and 12 form stable complex independent of the non-translated regions of viral RNA and other viral proteins Tan, Yong Wah; Fung, To Sing; Shen, Hongyuan; Huang, Mei; Liu, Ding Xiang 2018 2018-01-01 PMC N PMC7112110 29035788.0 10.1016/j.virol.2017.10.004 flw7eejq 0.591487
16 Bouvet_2010 In Vitro Reconstitution of SARS-Coronavirus mRNA Cap Methylation Bouvet, Mickaël; Debarnot, Claire; Imbert, Isabelle; Selisko, Barbara; Snijder, Eric J.; Canard, Bruno; Decroly, Etienne 2010 2010-04-22 COMM-USE N PMC2858705 20421945.0 10.1371/journal.ppat.1000863 4bripmvh 0.570063
17 Gao_Y_2020 Structure of RNA-dependent RNA polymerase from 2019-nCoV, a major antiviral drug target Yan Gao; Liming Yan; Yucen Huang; Fengjiang Liu; Yao Zhao; Lin Cao; Tao Wang; Qianqian Sun; Zhenhua Ming; Lianqi Zhang; Ji Ge; Litao Zheng; Ying Zhang; Haofeng Wang; Yan Zhu; Chen Zhu; Tianyu Hu; Tian Hua; Bing Zhang; Xiuna Yang; Jun Li; Haitao Yang; Zhijie Liu; Wenqing Xu; Luke W. Guddat; Quan Wang; Zhiyong Lou; Zihe Rao 2020 2020-03-17 BioRxiv Y 10.1101/2020.03.16.993386 glfxrla9 0.562223
18 Noble_2014 Crystal structure of dengue virus methyltransferase without S-adenosyl-L-methionine Noble, Christian G.; Li, Shi-Hua; Dong, Hongping; Chew, Sock Hui; Shi, Pei-Yong 2014 2014-11-30 PMC N PMC7113791 25241250.0 10.1016/j.antiviral.2014.09.003 oxohdfpu 0.532559 Deng_2019, Milani_2009, Someya_2008
19 Kirchdoerfer_2019 Structure of the SARS-CoV nsp12 polymerase bound to nsp7 and nsp8 co-factors Kirchdoerfer, Robert N.; Ward, Andrew B. 2019 2019-05-28 None N PMC6538669 31138817.0 10.1038/s41467-019-10280-3 gybjij1l 0.529790
20 Punekar_2012 Crystal structure of RlmM, the 2′O-ribose methyltransferase for C2498 of Escherichia coli 23S rRNA Punekar, Avinash S.; Shepherd, Tyson R.; Liljeruhm, Josefine; Forster, Anthony C.; Selmer, Maria 2012 2012-08-24 NONCOMM N PMC3488215 22923526.0 10.1093/nar/gks727 plg5qx9m 0.483148 Sato_2019 Someya_2008, Kanitz_2019, Myllykoski_2017, Scrima_2004
21 Bouvet_2014 Coronavirus Nsp10, a Critical Co-factor for Activation of Multiple Replicative Enzymes Bouvet, Mickaël; Lugari, Adrien; Posthuma, Clara C.; Zevenhoven, Jessika C.; Bernard, Stéphanie; Betzi, Stéphane; Imbert, Isabelle; Canard, Bruno; Guillemot, Jean-Claude; Lécine, Patrick; Pfefferle, Susanne; Drosten, Christian; Snijder, Eric J.; Decroly, Etienne; Morelli, Xavier 2014 2014-07-29 PMC N PMC4162180 25074927.0 10.1074/jbc.m114.577353 udwomjop 0.472076
22 Murphy_2010 Sequence–function analysis of the Sendai virus L protein domain VI Murphy, Andrea M.; Moerdyk-Schauwecker, Megan; Mushegian, Arcady; Grdzelishvili, Valery Z. 2010 2010-09-30 PMC N PMC2923248 20609457.0 10.1016/j.virol.2010.06.019 l5y3qkde 0.464386
23 Milani_2009 Flaviviral methyltransferase/RNA interaction: Structural basis for enzyme inhibition Milani, Mario; Mastrangelo, Eloise; Bollati, Michela; Selisko, Barbara; Decroly, Etienne; Bouvet, Mickaël; Canard, Bruno; Bolognesi, Martino 2009 2009-07-31 PMC N PMC7127253 19501254.0 10.1016/j.antiviral.2009.03.001 tf4jl47v 0.450987 Noble_2014, Deng_2019
24 Ke_M_2012 Short peptides derived from the interaction domain of SARS coronavirus nonstructural protein nsp10 can suppress the 2′-O-methyltransferase activity of nsp10/nsp16 complex Ke, Min; Chen, Yu; Wu, Andong; Sun, Ying; Su, Ceyang; Wu, Hao; Jin, Xu; Tao, Jiali; Wang, Yi; Ma, Xiao; Pan, Ji-An; Guo, Deyin 2012 2012-08-31 PMC N PMC7114426 22659295.0 10.1016/j.virusres.2012.05.017 z5109axc 0.447444
25 Aik_W_2017 The N-terminal domains of FLASH and Lsm11 form a 2:1 heterotrimer for histone pre-mRNA 3’-end processing Aik, Wei Shen; Lin, Min-Han; Tan, Dazhi; Tripathy, Ashutosh; Marzluff, William F.; Dominski, Zbigniew; Chou, Chi-Yuan; Tong, Liang 2017 2017-10-11 COMM-USE N PMC5636114 29020104.0 10.1371/journal.pone.0186034 lg93okwg 0.435679 Sato_2019 Scrima_2004
26 Cheng_2005 Expression, purification, and characterization of SARS coronavirus RNA polymerase Cheng, Ao; Zhang, Wei; Xie, Youhua; Jiang, Weihong; Arnold, Eddy; Sarafianos, Stefan G.; Ding, Jianping 2005 2005-05-10 PMC N PMC7111802 15840516.0 10.1016/j.virol.2005.02.017 qt130ix6 0.425948 van_der_Linden_2014
27 Decroly_2011 Crystal Structure and Functional Analysis of the SARS-Coronavirus RNA Cap 2′-O-Methyltransferase nsp10/nsp16 Complex Decroly, Etienne; Debarnot, Claire; Ferron, François; Bouvet, Mickael; Coutard, Bruno; Imbert, Isabelle; Gluais, Laure; Papageorgiou, Nicolas; Sharff, Andrew; Bricogne, Gérard; Ortiz-Lombardia, Miguel; Lescar, Julien; Canard, Bruno 2011 2011-05-26 COMM-USE N PMC3102710 21637813.0 10.1371/journal.ppat.1002059 nof2qx93 0.422050 Chen_2011
28 Debarnot_2011 Crystallization and diffraction analysis of the SARS coronavirus nsp10–nsp16 complex Debarnot, Claire; Imbert, Isabelle; Ferron, François; Gluais, Laure; Varlet, Isabelle; Papageorgiou, Nicolas; Bouvet, Mickaël; Lescar, Julien; Decroly, Etienne; Canard, Bruno 2011 2011-02-25 PMC N PMC3053173 21393853.0 10.1107/s1744309111002867 cnj0e0s9 0.408253 Ricagno_2006, Yu_K_2012, Sutton_2004
29 Tremblay-Létourneau_2011 Virtual High-Throughput Screening Identifies Mycophenolic Acid as a Novel RNA Capping Inhibitor Tremblay-Létourneau, Maude; Despins, Simon; Bougie, Isabelle; Bisaillon, Martin 2011 2011-09-15 COMM-USE N PMC3174198 21935470.0 10.1371/journal.pone.0024806 4gjo72hx 0.390146 Deng_2019
30 Sutton_2004 The nsp9 Replicase Protein of SARS-Coronavirus, Structure and Functional Insights Sutton, Geoff; Fry, Elizabeth; Carter, Lester; Sainsbury, Sarah; Walter, Tom; Nettleship, Joanne; Berrow, Nick; Owens, Ray; Gilbert, Robert; Davidson, Andrew; Siddell, Stuart; Poon, Leo L.M.; Diprose, Jonathan; Alderton, David; Walsh, Martin; Grimes, Jonathan M.; Stuart, David I. 2004 2004-02-29 PMC N PMC7135010 14962394.0 10.1016/j.str.2004.01.016 ihwwfnbn 0.333257
31 Stewart_2015 Structure-based identification of functional residues in the nucleoside-2′-O-methylase domain of Bluetongue virus VP4 capping enzyme Stewart, Meredith E.; Roy, Polly 2015 2015-02-24 None N PMC4359970 25834778.0 10.1016/j.fob.2015.02.001 vzel6r43 0.303016 Someya_2008, Punekar_2012
32 Tang_2020 Helicase of Type 2 Porcine Reproductive and Respiratory Syndrome Virus Strain HV Reveals a Unique Structure Tang, Chenjun; Deng, Zengqin; Li, Xiaorong; Yang, Meiting; Tian, Zizi; Chen, Zhenhang; Wang, Guoguo; Wu, Wei; Feng, Wen-hai; Zhang, Gongyi; Chen, Zhongzhou 2020 2020-02-14 None N PMC7077220 32075207.0 10.3390/v12020215 i2dotk0k 0.301705