1 |
infection |
immune |
IRF3 |
receptors |
IFN-I |
type |
PRRSV |
rnase |
PKR |
bat |
RSV |
STAT1 |
ISG15 |
chicken |
IFIT1 |
2 |
virus |
viral |
nf-κb |
recognition |
dendritic |
ifns |
porcine |
rnase l |
DNA |
TLR3 |
TRIM25 |
DENV |
HIV-1 |
IBV |
IFITM3 |
3 |
cells |
host |
mers-cov |
nucleic |
pdcs |
IFN |
ifn-β |
OAS |
STING |
bats |
lncrnas |
HCMV |
FMDV |
chickens |
IFIT |
4 |
expression |
innate |
sars-cov |
RNA |
pdc |
III |
PEDV |
5A |
cgas |
poly |
ISG20 |
STAT2 |
OTU |
feline |
cap |
5 |
antiviral |
antiviral |
nuclear |
sensors |
mice |
ifn-λ |
pdcov |
- |
dsrna |
γ-pga |
ligase |
transducer |
ubiquitin-like |
cats |
methylation |
6 |
response |
viruses |
coronavirus |
prrs |
NK |
HCV |
nsp1 |
2 |
stress |
agonists |
NS1 |
dengue |
IPNV |
duck |
PRV |
7 |
replication |
review |
translocation |
acids |
plasmacytoid |
type i |
ifn-α |
rotavirus |
sensing |
TLR4 |
IAV |
dengue virus |
fc |
SAV3 |
IFIT3 |
8 |
viral |
recent |
syndrome |
RIG-I |
adaptive |
type i ifns |
reproductive |
synthetase |
cgas-sting |
rnai |
E3 |
ifnγ |
3cpro |
avian |
ifitms |
9 |
IFN |
system |
SARS |
RLR |
cell |
type iii ifn |
diarrhea |
ns2 |
RNA |
epithelial |
c-terminal |
STAT |
EGR1 |
ATMUV |
PIV5 |
10 |
effect |
mechanisms |
factor |
rlrs |
dendritic cells |
type i ifn |
nsp11 |
2–5A |
cyclic |
tlrs |
DUSP1 |
ifn-γ |
HERC5 |
post |
JE |
11 |
interferon |
signaling |
TBK1 |
MDA5 |
MCMV |
ifnλ4 |
swine |
enzyme |
synthase |
ICLC |
ubiquitin |
JAK/STAT |
mxa |
mx |
2′-o-methylation |
12 |
gene |
immunity |
nuclear translocation |
pattern |
plasmacytoid dendritic cells |
type iii ifns |
respiratory syndrome virus |
oligoadenylate |
p4a |
airways |
HTNV |
NS5 |
TRIM21 |
birds |
- |
13 |
induced |
response |
activation |
cytosolic |
cells |
hcv infection |
TGEV |
HBV |
cgamp |
TLR9 |
RABV |
USP18 |
activity |
trachea |
1BB |
14 |
levels |
infections |
coronaviruses |
pattern recognition receptors |
responses |
IFNL |
pigs |
* |
double-stranded |
bovine |
RIG-I |
jak/stat pathway |
BFA |
24 |
interferon-inducible |
15 |
influenza |
strategies |
respiratory |
rig-i-like |
systemic |
lambda |
piglets |
L. |
ER |
bat cells |
ubiquitination |
STAT3 |
apol9 |
dukpna4 |
2′-O |
16 |
induction |
responses |
IFN |
helicases |
macrophages |
ifn-λ3 |
S100A9 |
dsrna |
PACT |
exacerbations |
domains |
DENV-2 |
ifn-ω |
36 |
methylated |
17 |
infected |
understanding |
plpro |
pathogen-associated |
dcs |
gut |
promoter activity |
MHV |
eif2α |
myotis |
TRIM62 |
opcs |
l(pro |
FIP |
tetratricopeptide |
18 |
results |
including |
regulatory |
initiate |
lymphocytes |
hepatitis |
IPEC-J2 |
oas/rnase |
double-stranded rna |
RPE |
NEAT1 |
ISRE |
camel |
bronchitis |
translation |
19 |
vitro |
pathways |
ikkε |
rig-i-like receptors |
antigen |
hepatitis c virus |
CBP |
AKAP7 |
dna sensors |
epithelial cells |
k63-linked |
n-myc |
sc |
12 |
pifitm1 |
20 |
data |
virus |
severe |
molecular |
CD200 |
II |
PRRS |
OAS1 |
endoplasmic |
poly iclc |
rna-binding |
janus |
conjugation |
PCR |
IFIT1B |
21 |
increased |
diseases |
proteins |
patterns |
acute |
treatment |
epidemic |
RNA |
IFI16 |
RV |
domain |
nmi |
CHIKV |
to-cells |
ifits |
22 |
show |
proteins |
protein |
pamps |
DC |
genes |
promoter |
oligoadenylates |
ASFV |
alecto |
TRIM56 |
HCQ |
antibody |
ducks |
IFITM |
23 |
demonstrated |
interferons |
transcription |
intracellular |
ifnα |
infants |
pams |
ribonuclease |
MAV-1 |
agonist |
lncrna |
ALVAC |
ADCP |
nitric |
ISG56/IFIT1 |
24 |
study |
discuss |
protease |
recognize |
myeloid |
sars-cov-2 |
industry |
oas proteins |
interferon genes |
mmbr |
sev |
activator of transcription |
antiviral activity |
oxide |
mrnas |
25 |
in vitro |
pathogens |
nucleus |
cascades |
clearance |
ifn pathway |
protein |
srnase |
DDX3 |
COPD |
HACE1 |
activator |
ifn-induced |
resiquimod |
+ |
26 |
genes |
functions |
phosphorylation |
toll-like |
RBD |
iii ifns |
economic |
hepatitis |
kinase |
mammals |
GLTSCR2 |
ifn-α |
hiv-1 infection |
hcov-oc43 |
p53 |
27 |
ISG |
viral infection |
east |
NLRP3 |
type |
allele |
prion |
degradation |
dsdna |
rpe cells |
long |
signal transducer |
boifn-ω3 |
ALV-J |
users |
28 |
isgs |
cellular |
production |
toll-like receptors |
early |
YFV-17D |
ipec-j2 cells |
2′,5′-oligoadenylate |
reticulum |
reservoir |
respiratory syncytial virus |
SOCS-3 |
SVV |
infectious bronchitis virus |
online version |
29 |
mrna |
roles |
PLP2 |
PRR |
in vivo |
stat1-deficient |
nucleocapsid |
2′-5′ |
rna viruses |
cpg-c41 |
syncytial |
pathway |
α-defensins |
8 |
SUPPLEMENTARY |
30 |
type |
pathogenesis |
TRAF3 |
acid |
HBD |
ifn-λs |
inhibited |
AZA |
stimulator |
IRAK-4 |
zbtrim25 |
PBMC |
ubiquitin |
days |
IFIT2 |
31 |
vivo |
defense |
kinase |
inflammasome |
ifn-α/β |
IFNL4 |
n protein |
single-stranded |
cytosolic dna |
peritoneal |
aptamers |
STAT4 |
subtypes |
jak/stat |
tetratricopeptide repeats |
32 |
compared |
immune response |
middle |
pathogen-associated molecular patterns |
production |
chronic |
pdcov infection |
double-stranded |
synthesis |
temperature |
HFRS |
UL23 |
trim5α |
dpi |
nm |
33 |
mice |
infection |
DUB |
nucleic acids |
viral clearance |
animal |
deltacoronavirus |
OAS3 |
viral dsrna |
HRV-16 |
TRIM41 |
phosphorylation |
ADP |
avbds |
5′ |
34 |
role |
signalling |
ifn-β |
clrs |
nk cell |
tract |
bicp0 |
oas-rnase |
biogenesis |
EBV |
e3 ligase activity |
FHV-1 |
conjugated |
2216 |
‘ |
35 |
activity |
effector |
inhibits |
TLR |
CD200R |
progression |
marc-145 cells |
ns4b |
cyclic gmp |
viral dsrnas |
positive |
metypcp |
antiretroviral |
ISR2 |
4 |
36 |
human |
evolved |
3 |
lectin |
sepsis |
inflammation |
nsp1β |
rnase l. |
TRBP |
aminoglycoside |
MAVS |
IRF-1 |
species |
DTMUV |
N1 |
37 |
CNS |
pathogen |
interferon regulatory factor 3 |
endosomal |
nk cells |
type iii interferons |
syndrome |
endou |
indomethacin |
-λ |
motif |
ifn‐λ4 |
enzymes |
degs |
e(rns |
38 |
robust |
development |
middle east respiratory syndrome coronavirus |
c-type |
ifn-αβ |
ifnλs |
porcine deltacoronavirus |
decay |
phosphorylates |
TLR-3 |
trafs |
asian |
hundreds |
MDM |
PPP-RNA |
39 |
model |
role |
induction |
tlrs |
t cells |
ifn-λ4 |
transmissible |
enzymes |
cgas-sting pathway |
CLEC2 |
mir‐30 |
ifn-stimulated response element |
protein |
hpi |
caspase-1 |
40 |
higher |
current |
found |
inflammatory |
monocytes |
ifnλ |
swine industry |
PDE |
GMP |
lines |
lab-attenuated |
CD147 |
P2Y(13 |
defs |
unmodified |
41 |
wild-type |
structural |
papain-like |
LGP2 |
type i ifn |
glucocorticoids |
nsp16 |
mouse hepatitis virus |
translation |
toll-like |
RNF166 |
alt |
conjugates |
igy |
viral rna |
42 |
ZIKV |
highlight |
SFSV |
signaling cascades |
RRV |
interferons |
prrsv-infected |
exon |
cytosolic |
humans |
zebrafish |
human cytomegalovirus |
E1 |
DF-1 |
article |
43 |
activation |
escape |
interferon |
cytokines |
CD4 |
lambdas |
prig-i |
oas/rnase l pathway |
protein |
toll/il-1 |
NSP1 |
sat05f |
antigenically |
ovo |
structures |
44 |
lacking |
research |
sars-cov infection |
c-type lectin receptors |
expansion |
snps |
isolate |
exon(- |
armenia/07 |
IRAK-M |
sendai |
inflammatory |
α-defensin |
NDV |
2′-o-methyltransferase |
45 |
decreased |
years |
nss |
danger |
LDV |
sclerosis |
pdcov n protein |
prostate |
primates |
CLEC5A |
protein |
driven |
ifn-α1 |
inos |
shrna |
46 |
knockdown |
developed |
C6 |
receptor |
infections |
multiple sclerosis |
oct-1 |
synthetases |
er stress |
irak-4-deficient |
TRAF3 |
RIG-1 |
foot-and-mouth disease virus |
downregulated |
parps |
47 |
viruses |
replication |
4b |
pathogens |
pdcss |
due |
infection |
5AMD |
NTZ |
serine |
trim25-mediated |
NB |
ifna1 |
upregulated |
paid |
48 |
neurons |
autophagy |
orf4b |
signaling |
vlps |
functions |
production |
dsrna-dependent |
lassa |
becs |
long noncoding rnas |
MX |
madv-1 |
TLR |
ELECTRONIC |
49 |
microglia |
interferon |
bctraf3 |
nod-like |
lymphocyte |
human |
ifn-β1 |
mutant |
sec16a |
5′ppprna |
NRAV |
transcription |
foot-and-mouth |
ODN |
reveal |
50 |
astrocytes |
immune system |
ifn regulatory factor 3 |
adaptors |
CD8 |
biological activities |
showed |
ankyrin |
sgs |
CF |
CRFB1 |
cytokine |
peptides |
ligands |
binding |