1 |
Chien_2020 |
Nucleotide Analogues as Inhibitors of SARS-CoV-2 Polymerase |
Minchen Chien; Thomas K. Anderson; Steffen Jockusch; Chuanjuan Tao; Shiv Kumar; Xiaoxu Li; James J. Russo; Robert Kirchdoerfer; Jingyue Ju |
2020 |
2020-03-20 |
BioRxiv |
Y |
|
|
10.1101/2020.03.18.997585 |
8prn86g6 |
0.733336 |
|
|
2 |
Lucas-Hourani_2017 |
Original Chemical Series of Pyrimidine Biosynthesis Inhibitors That Boost the Antiviral Interferon Response |
Lucas-Hourani, Marianne; Dauzonne, Daniel; Munier-Lehmann, Hélène; Khiar, Samira; Nisole, Sébastien; Dairou, Julien; Helynck, Olivier; Afonso, Philippe V.; Tangy, Frédéric; Vidalain, Pierre-Olivier |
2017 |
2017-09-22 |
None |
N |
PMC5610480 |
28807907.0 |
10.1128/aac.00383-17 |
jiqql1pr |
0.693879 |
|
Liu_Q_2020, Hamada_2013 |
3 |
Jockusch_2020 |
Triphosphates of the Two Components in DESCOVY and TRUVADA are Inhibitors of the SARS-CoV-2 Polymerase |
Steffen Jockusch; Chuanjuan Tao; Xiaoxu Li; Thomas K. Anderson; Minchen Chien; Shiv Kumar; James J. Russo; Robert Kirchdoerfer; Jingyue Ju |
2020 |
2020-04-05 |
BioRxiv |
Y |
|
|
10.1101/2020.04.03.022939 |
awbcw3gq |
0.658721 |
|
|
4 |
Liu_Q_2020 |
Enhancing the Antiviral Efficacy of RNA-Dependent RNA Polymerase Inhibition by Combination with Modulators of Pyrimidine Metabolism |
Qi Liu; Amita Gupta; Ayse Okesli-Armlovich; Wenjie Qiao; Curt R. Fischer; Mark Smith; Jan E. Carette; Michael C. Bassik; Chaitan Khosla |
2020 |
2020-03-25 |
BioRxiv |
N |
|
|
10.1101/2020.03.24.992230 |
1zk64gsg |
0.648917 |
|
|
5 |
Good_2020 |
Preclinical evaluation of AT-527, a novel guanosine nucleotide prodrug with potent, pan-genotypic activity against hepatitis C virus |
Good, Steven S.; Moussa, Adel; Zhou, Xiao-Jian; Pietropaolo, Keith; Sommadossi, Jean-Pierre |
2020 |
2020-01-08 |
COMM-USE |
N |
PMC6949113 |
31914458.0 |
10.1371/journal.pone.0227104 |
lxtuig9w |
0.641892 |
|
Obeid_2011 |
6 |
Picard-Jean_2013 |
The Immunosuppressive Agent Mizoribine Monophosphate Is an Inhibitor of the Human RNA Capping Enzyme |
Picard-Jean, Frédéric; Bougie, Isabelle; Shuto, Satoshi; Bisaillon, Martin |
2013 |
2013-01-17 |
COMM-USE |
N |
PMC3547949 |
23349942.0 |
10.1371/journal.pone.0054621 |
dr2uow4m |
0.630238 |
|
Sticher_2020 |
7 |
Vliegen_2009 |
Substituted imidazopyridines as potent inhibitors of HCV replication |
Vliegen, Inge; Paeshuyse, Jan; De Burghgraeve, Tine; Lehman, Laura S.; Paulson, Matthew; Shih, I-Hung; Mabery, Eric; Boddeker, Nina; De Clercq, Erik; Reiser, Hans; Oare, David; Lee, William A.; Zhong, Weidong; Bondy, Steven; Pürstinger, Gerhard; Neyts, Johan |
2009 |
2009-05-31 |
PMC |
N |
PMC7114863 |
19303654.0 |
10.1016/j.jhep.2008.12.028 |
j09mf1ad |
0.612772 |
|
Obeid_2011, Tonelli_2017 |
8 |
Sun_J_2011 |
Inhibition of hepatitis C virus replication by Monascus pigment derivatives that interfere with viral RNA polymerase activity and the mevalonate biosynthesis pathway |
Sun, Ji-Min; Kim, Seong-Jun; Kim, Geon-Woo; Rhee, Jin-Kyu; Kim, Nam Doo; Jung, Heeyong; Jeun, Jungae; Lee, Seung-Hoon; Han, Seung Hyun; Shin, Chul Soo; Oh, Jong-Won |
2011 |
2011-11-09 |
PMC |
N |
PMC7109977 |
22076990.0 |
10.1093/jac/dkr432 |
8hiymqyb |
0.610479 |
|
Obeid_2011 |
9 |
Obeid_2011 |
Inhibition of hepatitis C virus replication by semi-synthetic derivatives of glycopeptide antibiotics |
Obeid, Susan; Printsevskaya, Svetlana S.; Olsufyeva, Eugenia N.; Dallmeier, Kai; Durantel, David; Zoulim, Fabien; Preobrazhenskaya, Maria N.; Neyts, Johan; Paeshuyse, Jan |
2011 |
2011-03-24 |
PMC |
N |
PMC7109641 |
21436155.0 |
10.1093/jac/dkr104 |
slnde4dc |
0.607058 |
|
|
10 |
Yoshida_2019 |
Selective and competitive inhibition of kynurenine aminotransferase 2 by glycyrrhizic acid and its analogues |
Yoshida, Yukihiro; Fujigaki, Hidetsugu; Kato, Koichi; Yamazaki, Kyoka; Fujigaki, Suwako; Kunisawa, Kazuo; Yamamoto, Yasuko; Mouri, Akihiro; Oda, Akifumi; Nabeshima, Toshitaka; Saito, Kuniaki |
2019 |
2019-07-15 |
COMM-USE |
N |
PMC6629613 |
31308447.0 |
10.1038/s41598-019-46666-y |
ytto4ktu |
0.588866 |
|
Kim_J_2019, Pascual_2017 |
11 |
Shin_2018 |
Gemcitabine and Nucleos(t)ide Synthesis Inhibitors Are Broad-Spectrum Antiviral Drugs that Activate Innate Immunity |
Shin, Hye Jin; Kim, Chonsaeng; Cho, Sungchan |
2018 |
2018-04-20 |
COMM-USE |
N |
PMC5923505 |
29677162.0 |
10.3390/v10040211 |
g9a72xf6 |
0.516811 |
|
Lee_K_2017 |
12 |
Lee_K_2017 |
Gemcitabine, a broad-spectrum antiviral drug, suppresses enterovirus infections through innate immunity induced by the inhibition of pyrimidine biosynthesis and nucleotide depletion |
Lee, Kyungjin; Kim, Dong-Eun; Jang, Kyoung-Soon; Kim, Seong-Jun; Cho, Sungchan; Kim, Chonsaeng |
2017 |
2017-12-15 |
COMM-USE |
N |
PMC5777774 |
29383162.0 |
10.18632/oncotarget.23258 |
jv76j6wx |
0.499680 |
|
Liu_Q_2020, Shin_2018 |
13 |
Wang_2018 |
Structure-activity relationships of cryptopleurine analogs with E-ring modifications as anti-hepatitis C virus agents |
Wang, Ying; Chen, Shao-Ru; Yang, Xiaoming; Lee, Kuo-Hsiung; Cheng, Yung-Chi |
2018 |
2018-02-01 |
PMC |
N |
|
29317151.0 |
10.1016/j.bmc.2017.12.027 |
9vssue3m |
0.455096 |
|
|
14 |
Tanner_2005 |
The Adamantane-Derived Bananins Are Potent Inhibitors of the Helicase Activities and Replication of SARS Coronavirus |
Tanner, Julian A.; Zheng, Bo-Jian; Zhou, Jie; Watt, Rory M.; Jiang, Jie-Qing; Wong, Kin-Ling; Lin, Yong-Ping; Lu, Lin-Yu; He, Ming-Liang; Kung, Hsiang-Fu; Kesel, Andreas J.; Huang, Jian-Dong |
2005 |
2005-03-31 |
None |
N |
PMC7110988 |
15797214.0 |
10.1016/j.chembiol.2005.01.006 |
3oiivkn2 |
0.431522 |
|
Opsenica_2011 |
15 |
Rieux_2020 |
Thiopurine Derivative-Induced Fpg/Nei DNA Glycosylase Inhibition: Structural, Dynamic and Functional Insights |
Rieux, Charlotte; Goffinont, Stéphane; Coste, Franck; Tber, Zahira; Cros, Julien; Roy, Vincent; Guérin, Martine; Gaudon, Virginie; Bourg, Stéphane; Biela, Artur; Aucagne, Vincent; Agrofoglio, Luigi; Garnier, Norbert; Castaing, Bertrand |
2020 |
2020-03-17 |
COMM-USE |
N |
PMC7139703 |
32192183.0 |
10.3390/ijms21062058 |
97qegnlo |
0.428368 |
|
|
16 |
Kim_M_2011 |
2,6-Bis-arylmethyloxy-5-hydroxychromones with antiviral activity against both hepatitis C virus (HCV) and SARS-associated coronavirus (SCV) |
Kim, Mi Kyoung; Yu, Mi-Sun; Park, Hye Ri; Kim, Kyung Bo; Lee, Chaewoon; Cho, Suh Young; Kang, Jihoon; Yoon, Hyunjun; Kim, Dong-Eun; Choo, Hyunah; Jeong, Yong-Joo; Chong, Youhoon |
2011 |
2011-11-30 |
PMC |
N |
PMC7115508 |
21925774.0 |
10.1016/j.ejmech.2011.09.005 |
garchpin |
0.412206 |
|
Mehellou_2010, Ikejiri_2007, Tsoukala_2010 |
17 |
Lin_J_2008 |
Inhibitory effects of some derivatives of glycyrrhizic acid against Epstein-Barr virus infection: Structure–activity relationships |
Lin, Jung-Chung; Cherng, Jaw-Ming; Hung, Man-Shan; Baltina, Lidia A.; Baltina, Lia; Kondratenko, Rimma |
2008 |
2008-07-31 |
PMC |
N |
PMC7114209 |
18423902.0 |
10.1016/j.antiviral.2008.01.160 |
jzmwy4yi |
0.411244 |
|
|
18 |
Baltina_2015 |
Glycyrrhizic acid derivatives as influenza A/H1N1 virus inhibitors |
Baltina, Lidia A.; Zarubaev, Vladimir V.; Baltina, Lia A.; Orshanskaya, Iana A.; Fairushina, Alina I.; Kiselev, Oleg I.; Yunusov, Marat S. |
2015 |
2015-04-15 |
PMC |
N |
PMC7127794 |
25801933.0 |
10.1016/j.bmcl.2015.02.074 |
d6do1xad |
0.406394 |
Lin_D_2012 |
Lin_J_2008, Pérez-Faginas_2011 |
19 |
Lee_C_2009 |
Aryl diketoacids (ADK) selectively inhibit duplex DNA-unwinding activity of SARS coronavirus NTPase/helicase |
Lee, Chaewoon; Lee, Jin Moo; Lee, Na-Ra; Jin, Bong-Suk; Jang, Kyoung Jin; Kim, Dong-Eun; Jeong, Yong-Joo; Chong, Youhoon |
2009 |
2009-03-15 |
PMC |
N |
PMC7127030 |
19233643.0 |
10.1016/j.bmcl.2009.02.010 |
r0r6sqxp |
0.392608 |
|
|
20 |
Hartman_2016 |
Preclinical evaluation of a mercaptobenzamide and its prodrug for NCp7-targeted inhibition of human immunodeficiency virus |
Hartman, T.L.; Yang, L.; Helfrick, A.N.; Hassink, M.; Shank, N.I.; George Rosenker, K.; Scerba, M.T.; Saha, M.; Hughes, E.; Wang, A.Q.; Xu, X.; Gupta, P.; Buckheit, R.W.; Appella, D.H. |
2016 |
2016-10-31 |
PMC |
N |
PMC7113734 |
27568924.0 |
10.1016/j.antiviral.2016.08.022 |
45glufnh |
0.321926 |
|
|