Topic 11 -- Abstracts with Biological Entities (English) - 75 Topics / Sub-Topic Model 54 - 15 Topics

cite ad title authors publish year publish time dataset abstract mentions covid pmcid pubmed id doi cord uid topic weight Similarity scispacy Similarity specter
1 Chien_2020 Nucleotide Analogues as Inhibitors of SARS-CoV-2 Polymerase Minchen Chien; Thomas K. Anderson; Steffen Jockusch; Chuanjuan Tao; Shiv Kumar; Xiaoxu Li; James J. Russo; Robert Kirchdoerfer; Jingyue Ju 2020 2020-03-20 BioRxiv Y 10.1101/2020.03.18.997585 8prn86g6 0.733336
2 Lucas-Hourani_2017 Original Chemical Series of Pyrimidine Biosynthesis Inhibitors That Boost the Antiviral Interferon Response Lucas-Hourani, Marianne; Dauzonne, Daniel; Munier-Lehmann, Hélène; Khiar, Samira; Nisole, Sébastien; Dairou, Julien; Helynck, Olivier; Afonso, Philippe V.; Tangy, Frédéric; Vidalain, Pierre-Olivier 2017 2017-09-22 None N PMC5610480 28807907.0 10.1128/aac.00383-17 jiqql1pr 0.693879 Liu_Q_2020, Hamada_2013
3 Jockusch_2020 Triphosphates of the Two Components in DESCOVY and TRUVADA are Inhibitors of the SARS-CoV-2 Polymerase Steffen Jockusch; Chuanjuan Tao; Xiaoxu Li; Thomas K. Anderson; Minchen Chien; Shiv Kumar; James J. Russo; Robert Kirchdoerfer; Jingyue Ju 2020 2020-04-05 BioRxiv Y 10.1101/2020.04.03.022939 awbcw3gq 0.658721
4 Liu_Q_2020 Enhancing the Antiviral Efficacy of RNA-Dependent RNA Polymerase Inhibition by Combination with Modulators of Pyrimidine Metabolism Qi Liu; Amita Gupta; Ayse Okesli-Armlovich; Wenjie Qiao; Curt R. Fischer; Mark Smith; Jan E. Carette; Michael C. Bassik; Chaitan Khosla 2020 2020-03-25 BioRxiv N 10.1101/2020.03.24.992230 1zk64gsg 0.648917
5 Good_2020 Preclinical evaluation of AT-527, a novel guanosine nucleotide prodrug with potent, pan-genotypic activity against hepatitis C virus Good, Steven S.; Moussa, Adel; Zhou, Xiao-Jian; Pietropaolo, Keith; Sommadossi, Jean-Pierre 2020 2020-01-08 COMM-USE N PMC6949113 31914458.0 10.1371/journal.pone.0227104 lxtuig9w 0.641892 Obeid_2011
6 Picard-Jean_2013 The Immunosuppressive Agent Mizoribine Monophosphate Is an Inhibitor of the Human RNA Capping Enzyme Picard-Jean, Frédéric; Bougie, Isabelle; Shuto, Satoshi; Bisaillon, Martin 2013 2013-01-17 COMM-USE N PMC3547949 23349942.0 10.1371/journal.pone.0054621 dr2uow4m 0.630238 Sticher_2020
7 Vliegen_2009 Substituted imidazopyridines as potent inhibitors of HCV replication Vliegen, Inge; Paeshuyse, Jan; De Burghgraeve, Tine; Lehman, Laura S.; Paulson, Matthew; Shih, I-Hung; Mabery, Eric; Boddeker, Nina; De Clercq, Erik; Reiser, Hans; Oare, David; Lee, William A.; Zhong, Weidong; Bondy, Steven; Pürstinger, Gerhard; Neyts, Johan 2009 2009-05-31 PMC N PMC7114863 19303654.0 10.1016/j.jhep.2008.12.028 j09mf1ad 0.612772 Obeid_2011, Tonelli_2017
8 Sun_J_2011 Inhibition of hepatitis C virus replication by Monascus pigment derivatives that interfere with viral RNA polymerase activity and the mevalonate biosynthesis pathway Sun, Ji-Min; Kim, Seong-Jun; Kim, Geon-Woo; Rhee, Jin-Kyu; Kim, Nam Doo; Jung, Heeyong; Jeun, Jungae; Lee, Seung-Hoon; Han, Seung Hyun; Shin, Chul Soo; Oh, Jong-Won 2011 2011-11-09 PMC N PMC7109977 22076990.0 10.1093/jac/dkr432 8hiymqyb 0.610479 Obeid_2011
9 Obeid_2011 Inhibition of hepatitis C virus replication by semi-synthetic derivatives of glycopeptide antibiotics Obeid, Susan; Printsevskaya, Svetlana S.; Olsufyeva, Eugenia N.; Dallmeier, Kai; Durantel, David; Zoulim, Fabien; Preobrazhenskaya, Maria N.; Neyts, Johan; Paeshuyse, Jan 2011 2011-03-24 PMC N PMC7109641 21436155.0 10.1093/jac/dkr104 slnde4dc 0.607058
10 Yoshida_2019 Selective and competitive inhibition of kynurenine aminotransferase 2 by glycyrrhizic acid and its analogues Yoshida, Yukihiro; Fujigaki, Hidetsugu; Kato, Koichi; Yamazaki, Kyoka; Fujigaki, Suwako; Kunisawa, Kazuo; Yamamoto, Yasuko; Mouri, Akihiro; Oda, Akifumi; Nabeshima, Toshitaka; Saito, Kuniaki 2019 2019-07-15 COMM-USE N PMC6629613 31308447.0 10.1038/s41598-019-46666-y ytto4ktu 0.588866 Kim_J_2019, Pascual_2017
11 Shin_2018 Gemcitabine and Nucleos(t)ide Synthesis Inhibitors Are Broad-Spectrum Antiviral Drugs that Activate Innate Immunity Shin, Hye Jin; Kim, Chonsaeng; Cho, Sungchan 2018 2018-04-20 COMM-USE N PMC5923505 29677162.0 10.3390/v10040211 g9a72xf6 0.516811 Lee_K_2017
12 Lee_K_2017 Gemcitabine, a broad-spectrum antiviral drug, suppresses enterovirus infections through innate immunity induced by the inhibition of pyrimidine biosynthesis and nucleotide depletion Lee, Kyungjin; Kim, Dong-Eun; Jang, Kyoung-Soon; Kim, Seong-Jun; Cho, Sungchan; Kim, Chonsaeng 2017 2017-12-15 COMM-USE N PMC5777774 29383162.0 10.18632/oncotarget.23258 jv76j6wx 0.499680 Liu_Q_2020, Shin_2018
13 Wang_2018 Structure-activity relationships of cryptopleurine analogs with E-ring modifications as anti-hepatitis C virus agents Wang, Ying; Chen, Shao-Ru; Yang, Xiaoming; Lee, Kuo-Hsiung; Cheng, Yung-Chi 2018 2018-02-01 PMC N 29317151.0 10.1016/j.bmc.2017.12.027 9vssue3m 0.455096
14 Tanner_2005 The Adamantane-Derived Bananins Are Potent Inhibitors of the Helicase Activities and Replication of SARS Coronavirus Tanner, Julian A.; Zheng, Bo-Jian; Zhou, Jie; Watt, Rory M.; Jiang, Jie-Qing; Wong, Kin-Ling; Lin, Yong-Ping; Lu, Lin-Yu; He, Ming-Liang; Kung, Hsiang-Fu; Kesel, Andreas J.; Huang, Jian-Dong 2005 2005-03-31 None N PMC7110988 15797214.0 10.1016/j.chembiol.2005.01.006 3oiivkn2 0.431522 Opsenica_2011
15 Rieux_2020 Thiopurine Derivative-Induced Fpg/Nei DNA Glycosylase Inhibition: Structural, Dynamic and Functional Insights Rieux, Charlotte; Goffinont, Stéphane; Coste, Franck; Tber, Zahira; Cros, Julien; Roy, Vincent; Guérin, Martine; Gaudon, Virginie; Bourg, Stéphane; Biela, Artur; Aucagne, Vincent; Agrofoglio, Luigi; Garnier, Norbert; Castaing, Bertrand 2020 2020-03-17 COMM-USE N PMC7139703 32192183.0 10.3390/ijms21062058 97qegnlo 0.428368
16 Kim_M_2011 2,6-Bis-arylmethyloxy-5-hydroxychromones with antiviral activity against both hepatitis C virus (HCV) and SARS-associated coronavirus (SCV) Kim, Mi Kyoung; Yu, Mi-Sun; Park, Hye Ri; Kim, Kyung Bo; Lee, Chaewoon; Cho, Suh Young; Kang, Jihoon; Yoon, Hyunjun; Kim, Dong-Eun; Choo, Hyunah; Jeong, Yong-Joo; Chong, Youhoon 2011 2011-11-30 PMC N PMC7115508 21925774.0 10.1016/j.ejmech.2011.09.005 garchpin 0.412206 Mehellou_2010, Ikejiri_2007, Tsoukala_2010
17 Lin_J_2008 Inhibitory effects of some derivatives of glycyrrhizic acid against Epstein-Barr virus infection: Structure–activity relationships Lin, Jung-Chung; Cherng, Jaw-Ming; Hung, Man-Shan; Baltina, Lidia A.; Baltina, Lia; Kondratenko, Rimma 2008 2008-07-31 PMC N PMC7114209 18423902.0 10.1016/j.antiviral.2008.01.160 jzmwy4yi 0.411244
18 Baltina_2015 Glycyrrhizic acid derivatives as influenza A/H1N1 virus inhibitors Baltina, Lidia A.; Zarubaev, Vladimir V.; Baltina, Lia A.; Orshanskaya, Iana A.; Fairushina, Alina I.; Kiselev, Oleg I.; Yunusov, Marat S. 2015 2015-04-15 PMC N PMC7127794 25801933.0 10.1016/j.bmcl.2015.02.074 d6do1xad 0.406394 Lin_D_2012 Lin_J_2008, Pérez-Faginas_2011
19 Lee_C_2009 Aryl diketoacids (ADK) selectively inhibit duplex DNA-unwinding activity of SARS coronavirus NTPase/helicase Lee, Chaewoon; Lee, Jin Moo; Lee, Na-Ra; Jin, Bong-Suk; Jang, Kyoung Jin; Kim, Dong-Eun; Jeong, Yong-Joo; Chong, Youhoon 2009 2009-03-15 PMC N PMC7127030 19233643.0 10.1016/j.bmcl.2009.02.010 r0r6sqxp 0.392608
20 Hartman_2016 Preclinical evaluation of a mercaptobenzamide and its prodrug for NCp7-targeted inhibition of human immunodeficiency virus Hartman, T.L.; Yang, L.; Helfrick, A.N.; Hassink, M.; Shank, N.I.; George Rosenker, K.; Scerba, M.T.; Saha, M.; Hughes, E.; Wang, A.Q.; Xu, X.; Gupta, P.; Buckheit, R.W.; Appella, D.H. 2016 2016-10-31 PMC N PMC7113734 27568924.0 10.1016/j.antiviral.2016.08.022 45glufnh 0.321926