Topic 09 -- Abstracts with Biological Entities (English) - 75 Topics / Sub-Topic Model 15 - 15 Topics

cite ad title authors publish year publish time dataset abstract mentions covid pmcid pubmed id doi cord uid topic weight Similarity scispacy Similarity specter
1 Kankanamalage_2015 Structure-Guided Design and Optimization of Dipeptidyl Inhibitors of Norovirus 3CL Protease. Structure-Activity Relationships and Biochemical, X-ray Crystallographic, Cell-Based, and In Vivo Studies Kankanamalage, Anushka C. Galasiti; Kim, Yunjeong; Weerawarna, Pathum M.; Uy, Roxanne Adeline Z.; Damalanka, Vishnu C.; Mandadapu, Sivakoteswara Rao; Alliston, Kevin R.; Mehzabeen, Nurjahan; Battaile, Kevin P.; Lovell, Scott; Chang, Kyeong-Ok; Groutas, William C. 2015 2015-03-19 PMC N PMC4484267 25761614.0 10.1021/jm5019934 ekjbxyfy 0.675242
2 Damalanka_2016 Oxadiazole-Based Cell Permeable Macrocyclic Transition State Inhibitors of Norovirus 3CL Protease Damalanka, Vishnu C.; Kim, Yunjeong; Alliston, Kevin R.; Weerawarna, Pathum M.; Galasiti Kankanamalage, Anushka C.; Lushington, Gerald H.; Mehzabeen, Nurjahan; Battaile, Kevin P.; Lovell, Scott; Chang, Kyeong-Ok; Groutas, William C. 2016 2016-02-08 PMC N PMC5156532 26823007.0 10.1021/acs.jmedchem.5b01464 aycioxsc 0.641436 Galasiti_Kankanamalage_2018
3 Galasiti_Kankanamalage_2017 Structure-Based Exploration and Exploitation of the S(4) Subsite of Norovirus 3CL Protease in the Design of Potent and Permeable Inhibitors Galasiti Kankanamalage, Anushka C.; Kim, Yunjeong; Rathnayake, Athri D.; Damalanka, Vishnu C.; Weerawarna, Pathum M.; Doyle, Sean T.; Alsoudi, Amer F.; Padmasankha Dissanayake, D. M.; Lushington, Gerald H.; Mehzabeen, Nurjahan; Battaile, Kevin P.; Lovell, Scott; Chang, Kyeong-Ok; Groutas, William C. 2017 2017-01-01 PMC N PMC5501333 27914364.0 10.1016/j.ejmech.2016.11.027 plbhi112 0.605158 Dove_2004 Kankanamalage_2015, Galasiti_Kankanamalage_2018
4 Menard_2012 Selective Inhibition of USP7 Menard, Robert; Sulea, Traian 2012 2012-04-20 PMC N PMC7111172 22520747.0 10.1016/j.chembiol.2012.04.001 jm9yxsf6 0.586226 Chen_2019, Goldenberg_2008
5 Weerawarna_2016 Structure-based design and synthesis of triazole-based macrocyclic inhibitors of norovirus protease: Structural, biochemical, spectroscopic, and antiviral studies Weerawarna, Pathum M.; Kim, Yunjeong; Galasiti Kankanamalage, Anushka C.; Damalanka, Vishnu C.; Lushington, Gerald H.; Alliston, Kevin R.; Mehzabeen, Nurjahan; Battaile, Kevin P.; Lovell, Scott; Chang, Kyeong-Ok; Groutas, William C. 2016 2016-08-25 None N PMC4916972 27235842.0 10.1016/j.ejmech.2016.04.013 iz4rd6u4 0.586217 Kankanamalage_2015, Damalanka_2016, Galasiti_Kankanamalage_2017, Galasiti_Kankanamalage_2018
6 Galasiti_Kankanamalage_2018 Structure-guided design of potent and permeable inhibitors of MERS coronavirus 3CL protease that utilize a piperidine moiety as a novel design element Galasiti Kankanamalage, Anushka C.; Kim, Yunjeong; Damalanka, Vishnu C.; Rathnayake, Athri D.; Fehr, Anthony R.; Mehzabeen, Nurjahan; Battaile, Kevin P.; Lovell, Scott; Lushington, Gerald H.; Perlman, Stanley; Chang, Kyeong-Ok; Groutas, William C. 2018 2018-04-25 None N PMC5891363 29544147.0 10.1016/j.ejmech.2018.03.004 bvh1o64r 0.495412 Shaw_2011, Li_C_2019
7 Zhang_2020 Crystal structure of SARS-CoV-2 main protease provides a basis for design of improved α-ketoamide inhibitors Zhang, Linlin; Lin, Daizong; Sun, Xinyuanyuan; Curth, Ute; Drosten, Christian; Sauerhering, Lucie; Becker, Stephan; Rox, Katharina; Hilgenfeld, Rolf 2020 2020-03-20 None Y PMC7164518 32198291.0 10.1126/science.abb3405 jlkpeh4j 0.488576
8 Ghosh_2012 Enhancing Protein Backbone Binding—A Fruitful Concept for Combating Drug‐Resistant HIV Ghosh, Arun K.; Anderson, David D.; Weber, Irene T.; Mitsuya, Hiroaki 2012 2012-01-31 PMC N PMC7159617 22290878.0 10.1002/anie.201102762 z0hxrrhy 0.478062
9 Manepalli_2011 Discovery of Novel Selective Serotonin Reuptake Inhibitors Through Development of a Protein-Based Pharmacophore Manepalli, Sankar; Geffert, Laura M.; Surratt, Christopher K.; Madura, Jeffry D. 2011 2011-09-02 PMC N PMC3183329 21834587.0 10.1021/ci200280m oa3h4o26 0.476312
10 Galasiti_Kankanamalage_2016 Anti-Norovirus Therapeutics: A Patent Review (2010–2015) Galasiti Kankanamalage, Anushka C.; Weerawarna, Pathum M.; Kim, Yunjeong; Chang, Kyeong-Ok; Groutas, William C. 2016 2016-02-25 PMC N PMC4948123 26881878.0 10.1517/13543776.2016.1153065 c7tc5a2t 0.454283 Weerasekara_2016, Wu_H_2016, Lee_C_2019
11 Carrasco_1994 Picornavirus inhibitors Carrasco, Luis 1994 1994-12-31 PMC N 7533301.0 10.1016/0163-7258(94)90040-x 43zrew96 0.419026
12 Deval_2017 Structure(s), function(s), and inhibition of the RNA-dependent RNA polymerase of noroviruses Deval, Jerome; Jin, Zhinan; Chuang, Ying-Chih; Kao, C. Cheng 2017 2017-04-15 PMC N PMC7114559 28041960.0 10.1016/j.virusres.2016.12.018 v28wbrqp 0.415780
13 Wang_2018 Bismuth antimicrobial drugs serve as broad-spectrum metallo-β-lactamase inhibitors Wang, Runming; Lai, Tsz-Pui; Gao, Peng; Zhang, Hongmin; Ho, Pak-Leung; Woo, Patrick Chiu-Yat; Ma, Guixing; Kao, Richard Yi-Tsun; Li, Hongyan; Sun, Hongzhe 2018 2018-01-30 COMM-USE N PMC5789847 29382822.0 10.1038/s41467-018-02828-6 k3dwwxar 0.385204 Fernández‐Oliva_2019 Peyclit_2019
14 Weerasekara_2016 Current Tools for Norovirus Drug Discovery Weerasekara, Sahani; Prior, Allan M.; Hua, Duy H. 2016 2016-05-02 PMC N PMC4931794 27108716.0 10.1080/17460441.2016.1178231 czvdj3v7 0.377664 Galasiti_Kankanamalage_2016, Venkataram_Prasad_2016
15 Chang_2019 Antiviral Drug Discovery: Norovirus Proteases and Development of Inhibitors Chang, Kyeong-Ok; Kim, Yunjeong; Lovell, Scott; Rathnayake, Athri D.; Groutas, William C. 2019 2019-02-25 COMM-USE N PMC6410195 30823509.0 10.3390/v11020197 r11lq8dd 0.376736 Lee_C_2019
16 Shannon_2020 Remdesivir and SARS-CoV-2: structural requirements at both nsp12 RdRp and nsp14 Exonuclease active-sites Shannon, Ashleigh; Tuyet Le, Nhung Thi; Selisko, Barbara; Eydoux, Cecilia; Alvarez, Karine; Guillemot, Jean-Claude; Decroly, Etienne; Peersen, Olve; Ferron, Francois; Canard, Bruno 2020 2020-04-10 PMC Y 10.1016/j.antiviral.2020.104793 rw37biop 0.326049
17 Rajnarayanan_2004 “Teaching old drugs to kill new bugs”: structure-based discovery of anti-SARS drugs Rajnarayanan, Rajendram V.; Dakshanamurthy, Sivanesan; Pattabiraman, Nagarajan 2004 2004-08-20 PMC N PMC7092804 15358186.0 10.1016/j.bbrc.2004.06.155 cqbayzat 0.320857 Park_2012, Ekins_2014 Tang_2020, Adhikari_2017
18 Tamilvanan_2013 High-throughput virtual screening and docking studies of matrix protein vp40 of ebola virus Tamilvanan, Thangaraju; Hopper, Waheeta 2013 2013-03-19 PMC N PMC3607187 23559747.0 10.6026/97320630009286 vk8wsgq9 0.315980
19 Bogoyevitch_2008 Inhibitors of c-Jun N-terminal kinases—JuNK no more? Bogoyevitch, Marie A.; Arthur, Peter G. 2008 2008-01-31 PMC N 17964301.0 10.1016/j.bbapap.2007.09.013 ivt25ghy 0.314103 Chen_2019
20 Su_H_2020 Discovery of baicalin and baicalein as novel, natural product inhibitors of SARS-CoV-2 3CL protease in vitro Haixia Su; Sheng Yao; Wenfeng Zhao; Minjun Li; Jia Liu; Weijuan Shang; Hang Xie; Changqiang Ke; Meina Gao; Kunqian Yu; Hong Liu; Jingshan Shen; Wei Tang; Leike Zhang; Jianping Zuo; Hualiang Jiang; Fang Bai; Yan Wu; Yang Ye; Yechun Xu 2020 2020-04-14 BioRxiv Y 10.1101/2020.04.13.038687 ixun0c8g 0.308537
21 Zhang_2015 A review on recent developments of indole-containing antiviral agents Zhang, Ming-Zhi; Chen, Qiong; Yang, Guang-Fu 2015 2015-01-07 PMC N PMC7115707 25462257.0 10.1016/j.ejmech.2014.10.065 rbdhdf6w 0.304242 Dove_2004 Liu_A_2012, Chattopadhyay_2009, Serban_2020, Bekut_2018
22 Bray_2010 Radiolabeled antiviral drugs and antibodies as virus-specific imaging probes Bray, Mike; Di Mascio, Michele; de Kok-Mercado, Fabian; Mollura, Daniel J.; Jagoda, Elaine 2010 2010-11-30 PMC N PMC7125728 20709111.0 10.1016/j.antiviral.2010.08.005 hqijd268 0.300796 Vardanyan_2016