Topic 03 -- Abstracts with Biological Entities (English) - 75 Topics / Sub-Topic Model 15 - 15 Topics

cite ad title authors publish year publish time dataset abstract mentions covid pmcid pubmed id doi cord uid topic weight Similarity scispacy Similarity specter
1 Takano_2013 Effect of chloroquine on feline infectious peritonitis virus infection in vitro and in vivo Takano, Tomomi; Katoh, Yasuichiroh; Doki, Tomoyoshi; Hohdatsu, Tsutomu 2013 2013-08-31 PMC N PMC7114111 23648708.0 10.1016/j.antiviral.2013.04.016 5t8yuq4v 0.892349 Falzarano_2015, Ekins_2015 Hsieh_2010, Wu_H_2016
2 Kim_S_2012 Enhanced inhibition of foot-and-mouth disease virus by combinations of porcine interferon-α and antiviral agents Kim, Su-Mi; Park, Jong-Hyeon; Lee, Kwang-Nyeong; Kim, Se-Kyung; Ko, Young-Joon; Lee, Hyang-Sim; Cho, In-Soo 2012 2012-11-30 PMC N PMC7114081 23000495.0 10.1016/j.antiviral.2012.09.009 oruqlb1j 0.873363 Choi_2018, Wu_H_2016
3 Fumian_2018 Potential Therapeutic Agents for Feline Calicivirus Infection Fumian, Tulio M.; Tuipulotu, Daniel Enosi; Netzler, Natalie E.; Lun, Jennifer H.; Russo, Alice G.; Yan, Grace J. H.; White, Peter A. 2018 2018-08-16 COMM-USE N PMC6116245 30115859.0 10.3390/v10080433 brgtwxhe 0.810166 Wu_H_2016, Hsieh_2010
4 Hsieh_2010 Synergistic antiviral effect of Galanthus nivalis agglutinin and nelfinavir against feline coronavirus Hsieh, Li-En; Lin, Chao-Nan; Su, Bi-Ling; Jan, Tong-Rong; Chen, Chi-Min; Wang, Ching-Ho; Lin, Dah-Sheng; Lin, Chung-Tien; Chueh, Ling-Ling 2010 2010-10-31 PMC N PMC7114315 20603153.0 10.1016/j.antiviral.2010.06.010 otoqejtg 0.805392 Wu_H_2016
5 Wu_H_2016 In vitro antiviral effect of germacrone on feline calicivirus Wu, Hongxia; Liu, Yongxiang; Zu, Shaopo; Sun, Xue; Liu, Chunguo; Liu, Dafei; Zhang, Xiaozhan; Tian, Jin; Qu, Liandong 2016 2016-03-21 PMC N PMC7087046 26997613.0 10.1007/s00705-016-2825-8 wgzpd6te 0.788490 Hsieh_2010
6 Livonesi_2007 In vitro and in vivo studies of the Interferon-alpha action on distinct Orthobunyavirus Livonesi, Márcia Cristina; Moro de Sousa, Ricardo Luiz; Badra, Soraya Jabur; Figueiredo, Luiz Tadeu Moraes 2007 2007-08-31 PMC N PMC7114330 17368573.0 10.1016/j.antiviral.2007.01.158 v4p01rze 0.740625 Wu_H_2016, Hsieh_2010
7 Li_L_2019 In vitro antiviral activity of Griffithsin against porcine epidemic diarrhea virus Li, Lan; Yu, Xiaoming; Zhang, Haoming; Cheng, Haiwei; Hou, Liting; Zheng, Qisheng; Hou, Jibo 2019 2019-01-14 PMC N PMC7089098 30637608.0 10.1007/s11262-019-01633-7 9mmktlhf 0.725075 Lee_C_2019, Lusvarghi_2016, Wu_H_2016
8 Momekov_2020 Ivermectin as a potential COVID-19 treatment from the pharmacokinetic point of view Georgi Momekov; Denitsa Momekova 2020 2020-04-17 BioRxiv Y 10.1101/2020.04.11.20061804 3hgmuyn4 0.715969 Ekins_2015, Pastuch-Gawołek_2019, Beigel_2010
9 Vigerust_2008 Chloroquine is effective against influenza A virus in vitro but not in vivo Vigerust, David J.; McCullers, Jonathan A. 2008 2008-01-21 PMC N PMC4941887 19453426.0 10.1111/j.1750-2659.2007.00027.x rf7kpyo4 0.693367 Perwitasari_2016, Takano_2013
10 Ekins_2020 Tilorone: A Broad-Spectrum Antiviral For Emerging Viruses Sean Ekins; Peter B. Madrid 2020 2020-03-11 BioRxiv N 10.1101/2020.03.09.984856 2suz20me 0.693146 Lee_C_2019, Blaising_2014
11 Li_Z_2008 Ribavirin Reduces Mortality in Enterovirus 71–Infected Mice by Decreasing Viral Replication Li, Zhao-Hong; Li, Chien-Ming; Ling, Pin; Shen, Fang-Hsiu; Chen, Shih-Heng; Liu, Ching-Chuan; Yu, Chun-Keung; Chen, Shun-Hua 2008 2008-03-15 PMC N PMC7109938 18279075.0 10.1086/527326 femlz8z2 0.676390 Takano_2013
12 Falzarano_2015 Lack of Protection Against Ebola Virus from Chloroquine in Mice and Hamsters Falzarano, Darryl; Safronetz, David; Prescott, Joseph; Marzi, Andrea; Feldmann, Friederike; Feldmann, Heinz 2015 2015-06-23 PMC N PMC4451918 25988934.0 10.3201/eid2106.150176 7b5yus4w 0.676314 Wang_2016, Ooi_E_2006 Takano_2013, Hsieh_2010, Wu_H_2016
13 Clementi_2020 Combined prophylactic and therapeutic use maximizes hydroxychloroquine anti-SARS-CoV-2 effects in vitro Nicola Clementi; Elena Criscuolo; Roberta Antonia Diotti; Roberto Ferrarese; Matteo Castelli; Roberto Burioni; Massimo Clementi; Nicasio Mancini 2020 2020-03-31 BioRxiv Y 10.1101/2020.03.29.014407 fhy2z49t 0.659656 Caly_2020
14 Choi_2018 Synergistic effect of ribavirin and vaccine for protection during early infection stage of foot-and-mouth disease Choi, Joo-Hyung; Jeong, Kwiwan; Kim, Su-Mi; Ko, Mi-Kyeong; You, Su-Hwa; Lyoo, Young S.; Kim, Byounghan; Ku, Jin-Mo; Park, Jong-Hyeon 2018 2018-11-28 NONCOMM N PMC6265586 30304889.0 10.4142/jvs.2018.19.6.788 hy708ia4 0.653195
15 Gonçalves_2020 Timing of antiviral treatment initiation is critical to reduce SARS-Cov-2 viral load Antonio Gonçalves; Julie Bertrand; Ruian Ke; Emmanuelle Comets; Xavier de Lamballerie; Denis Malvy; Andrés Pizzorno; Olivier Terrier; Manuel Rosa Calatrava; France Mentré; Patrick Smith; Alan S Perelson; Jérémie Guedj 2020 2020-04-07 BioRxiv Y 10.1101/2020.04.04.20047886 n6l2804j 0.626332 Goyal_2020
16 Keyaerts_2004 In vitro inhibition of severe acute respiratory syndrome coronavirus by chloroquine Keyaerts, Els; Vijgen, Leen; Maes, Piet; Neyts, Johan; Ranst, Marc Van 2004 2004-10-08 PMC N PMC7092815 15351731.0 10.1016/j.bbrc.2004.08.085 5lzzobl3 0.625976 Falzarano_2015, Ooi_E_2006, Wang_2016 Yamamoto_2004, Wu_H_2016
17 Vincent_2005 Chloroquine is a potent inhibitor of SARS coronavirus infection and spread Vincent, Martin J; Bergeron, Eric; Benjannet, Suzanne; Erickson, Bobbie R; Rollin, Pierre E; Ksiazek, Thomas G; Seidah, Nabil G; Nichol, Stuart T 2005 2005-08-22 COMM-USE N PMC1232869 16115318.0 10.1186/1743-422x-2-69 dgnddq80 0.625719 Yamamoto_2004, Hsieh_2010
18 Choy_2020 Remdesivir, lopinavir, emetine, and homoharringtonine inhibit SARS-CoV-2 replication in vitro Choy, Ka-Tim; Wong, Alvina Yin-Lam; Kaewpreedee, Prathanporn; Sia, Sin Fun; Chen, Dongdong; Hui, Kenrie Pui Yan; Chu, Daniel Ka Wing; Chan, Michael Chi Wai; Cheung, Peter Pak-Hang; Huang, Xuhui; Peiris, Malik; Yen, Hui-Ling 2020 2020-06-30 PMC Y 10.1016/j.antiviral.2020.104786 7e8zlt3t 0.622258 Falzarano_2015, Wang_2016, Ooi_E_2006, Martínez_2008 Hsieh_2010, Wu_H_2016
19 de_Wit_2018 Prophylactic and therapeutic efficacy of mAb treatment against MERS-CoV in common marmosets de Wit, Emmie; Feldmann, Friederike; Okumura, Atsushi; Horne, Eva; Haddock, Elaine; Saturday, Greg; Scott, Dana; Erlandson, Karl J.; Stahl, Neil; Lipsich, Leah; Kyratsous, Christos A.; Feldmann, Heinz 2018 2018-08-31 PMC N PMC7113689 29885377.0 10.1016/j.antiviral.2018.06.006 ch1omeec 0.589059 Koudstaal_2009 de_Wit_2020
20 Wang_2016 Antiviral activities of niclosamide and nitazoxanide against chikungunya virus entry and transmission Wang, Yu-Ming; Lu, Jeng-Wei; Lin, Chang-Chi; Chin, Yuan-Fan; Wu, Tzong-Yuan; Lin, Liang-In; Lai, Zheng-Zong; Kuo, Szu-Cheng; Ho, Yi-Jung 2016 2016-11-30 PMC N PMC7126800 27742486.0 10.1016/j.antiviral.2016.10.003 0lv2d091 0.588076 Wu_H_2016
21 Zhirnov_2005 High protection of animals lethally infected with influenza virus by aprotinin‐rimantadine combination Zhirnov, Oleg P. 2005 2005-12-07 PMC N PMC7166978 2434613.0 10.1002/jmv.1890210208 37ee05ev 0.576446
22 Saha_2016 Vector-delivered artificial miRNA effectively inhibited replication of Chikungunya virus Saha, Amrita; Bhagyawant, Sameer S.; Parida, Manmohan; Dash, Paban Kumar 2016 2016-10-31 PMC N PMC7113671 27565991.0 10.1016/j.antiviral.2016.08.019 z3hbjb30 0.551538 Wu_H_2016
23 Delvecchio_2016 Chloroquine, an Endocytosis Blocking Agent, Inhibits Zika Virus Infection in Different Cell Models Delvecchio, Rodrigo; Higa, Luiza M.; Pezzuto, Paula; Valadão, Ana Luiza; Garcez, Patrícia P.; Monteiro, Fábio L.; Loiola, Erick C.; Dias, André A.; Silva, Fábio J. M.; Aliota, Matthew T.; Caine, Elizabeth A.; Osorio, Jorge E.; Bellio, Maria; O’Connor, David H.; Rehen, Stevens; de Aguiar, Renato Santana; Savarino, Andrea; Campanati, Loraine; Tanuri, Amilcar 2016 2016-11-29 COMM-USE N PMC5192383 27916837.0 10.3390/v8120322 01s21vh0 0.546989
24 Cinatl_2003 Glycyrrhizin, an active component of liquorice roots, and replication of SARS-associated coronavirus Cinatl, J; Morgenstern, B; Bauer, G; Chandra, P; Rabenau, H; Doerr, HW 2003 2003-06-14 PMC N PMC7112442 12814717.0 10.1016/s0140-6736(03)13615-x c2q3ycfv 0.540029 Lee_C_2019, Wu_H_2016
25 Caly_2020 The FDA-approved drug ivermectin inhibits the replication of SARS-CoV-2 in vitro Caly, Leon; Druce, Julian D.; Catton, Mike G.; Jans, David A.; Wagstaff, Kylie M. 2020 2020-06-30 PMC Y 10.1016/j.antiviral.2020.104787 ivy95jpw 0.533098 Beigel_2010, Shaw_2011, García-Serradilla_2019 Tan_E_2004
26 de_Wit_2020 Prophylactic and therapeutic remdesivir (GS-5734) treatment in the rhesus macaque model of MERS-CoV infection de Wit, Emmie; Feldmann, Friederike; Cronin, Jacqueline; Jordan, Robert; Okumura, Atsushi; Thomas, Tina; Scott, Dana; Cihlar, Tomas; Feldmann, Heinz 2020 2020-03-24 COMM-USE Y PMC7104368 32054787.0 10.1073/pnas.1922083117 x50tvq3a 0.521847 de_Wit_2018, Omrani_2015
27 Xing_2020 Reversal of Infected Host Gene Expression Identifies Repurposed Drug Candidates for COVID-19 Jing Xing; Rama Shankar; Aleksandra Drelich; Shreya Paithankar; Eugene Chekalin; Thomas Dexheimer; Surender Rajasekaran; Chien-Te Kent Tseng; Bin Chen 2020 2020-04-09 BioRxiv Y 10.1101/2020.04.07.030734 dl6rbqxp 0.519134 Yamamoto_2004
28 Wang_2016 Teicoplanin inhibits Ebola pseudovirus infection in cell culture Wang, Yizhuo; Cui, Rui; Li, Guiming; Gao, Qianqian; Yuan, Shilin; Altmeyer, Ralf; Zou, Gang 2016 2016-01-31 PMC N PMC7113690 26585243.0 10.1016/j.antiviral.2015.11.003 t6ogxz7n 0.517392 Hsieh_2010, Wu_H_2016
29 Chen_2004 In vitro susceptibility of 10 clinical isolates of SARS coronavirus to selected antiviral compounds Chen, F; Chan, K.H; Jiang, Y; Kao, R.Y.T; Lu, H.T; Fan, K.W; Cheng, V.C.C; Tsui, W.H.W; Hung, I.F.N; Lee, T.S.W; Guan, Y; Peiris, J.S.M; Yuen, K.Y 2004 2004-09-30 PMC N PMC7128415 15288617.0 10.1016/j.jcv.2004.03.003 ot5pvtbl 0.516371 Sperber_1987, Wang_2016
30 Liu_R_2015 Mouse lung slices: An ex vivo model for the evaluation of antiviral and anti-inflammatory agents against influenza viruses Liu, Rui; An, Liwei; Liu, Ge; Li, Xiaoyu; Tang, Wei; Chen, Xulin 2015 2015-08-31 PMC N PMC7125926 26022197.0 10.1016/j.antiviral.2015.05.008 y6xuxj16 0.504358 Perwitasari_2016, Livonesi_2007
31 Ooi_E_2006 In vitro inhibition of human influenza A virus replication by chloroquine Ooi, Eng Eong; Chew, Janet Seok Wei; Loh, Jin Phang; Chua, Robert CS 2006 2006-05-29 COMM-USE N PMC1481635 16729896.0 10.1186/1743-422x-3-39 gvfz6qio 0.496609
32 Ferraris_2015 Evaluation of Crimean-Congo hemorrhagic fever virus in vitro inhibition by chloroquine and chlorpromazine, two FDA approved molecules Ferraris, O.; Moroso, M.; Pernet, O.; Emonet, S.; Ferrier Rembert, A.; Paranhos-Baccalà, G.; Peyrefitte, C.N. 2015 2015-06-30 PMC N PMC7113845 25796972.0 10.1016/j.antiviral.2015.03.005 h8zqis1p 0.491578 Wu_H_2016, Hsieh_2010
33 Tan_E_2004 Inhibition of SARS Coronavirus Infection In Vitro with Clinically Approved Antiviral Drugs Tan, Emily L.C.; Ooi, Eng Eong; Lin, Chin-Yo; Tan, Hwee Cheng; Ling, Ai Ee; Lim, Bing; Stanton, Lawrence W. 2004 2004-04-23 PMC N PMC3323075 15200845.0 10.3201/eid1004.030458 kcyao9i9 0.471370 Yamamoto_2004
34 Yamamoto_2004 HIV protease inhibitor nelfinavir inhibits replication of SARS-associated coronavirus Yamamoto, Norio; Yang, Rongge; Yoshinaka, Yoshiyuki; Amari, Shinji; Nakano, Tatsuya; Cinatl, Jindrich; Rabenau, Holger; Doerr, Hans Wilhelm; Hunsmann, Gerhard; Otaka, Akira; Tamamura, Hirokazu; Fujii, Nobutaka; Yamamoto, Naoki 2004 2004-06-04 PMC Y PMC7111005 15144898.0 10.1016/j.bbrc.2004.04.083 77cylm1o 0.463797 Tan_E_2004
35 Doménech_2011 Use of recombinant interferon omega in feline retrovirosis: From theory to practice Doménech, Ana; Miró, Guadalupe; Collado, Victorio M.; Ballesteros, Natalia; Sanjosé, Leticia; Escolar, Elena; Martin, Sonsoles; Gomez-Lucia, Esperanza 2011 2011-10-15 PMC N PMC7132444 21719116.0 10.1016/j.vetimm.2011.06.008 zfpcuhpy 0.458092
36 Cao_J_2015 A screen of the NIH Clinical Collection small molecule library identifies potential anti-coronavirus drugs Cao, Jianzhong; Forrest, J. Craig; Zhang, Xuming 2015 2015-02-28 PMC N PMC7113785 25451075.0 10.1016/j.antiviral.2014.11.010 79v0hdi9 0.457075 Yamamoto_2004
37 Boda_2018 Antiviral drug screening by assessing epithelial functions and innate immune responses in human 3D airway epithelium model Boda, Bernadett; Benaoudia, Sacha; Huang, Song; Bonfante, Rosy; Wiszniewski, Ludovic; Tseligka, Eirini D.; Tapparel, Caroline; Constant, Samuel 2018 2018-08-31 PMC N PMC7113743 29890184.0 10.1016/j.antiviral.2018.06.007 oh45ifkx 0.454175
38 Jurgeit_2012 Niclosamide Is a Proton Carrier and Targets Acidic Endosomes with Broad Antiviral Effects Jurgeit, Andreas; McDowell, Robert; Moese, Stefan; Meldrum, Eric; Schwendener, Reto; Greber, Urs F. 2012 2012-10-25 None N PMC3486884 23133371.0 10.1371/journal.ppat.1002976 zlygzsm1 0.453201 Jung_2019, Al‐Bari_2017, Lee_C_2019
39 Sallard_2020 Type 1 interferons as a potential treatment against COVID-19 Sallard, Erwan; Lescure, François-Xavier; Yazdanpanah, Yazdan; Mentre, France; Peiffer-Smadja, Nathan 2020 2020-06-30 PMC Y 10.1016/j.antiviral.2020.104791 a0ribcmv 0.440621 Beigel_2010 Martínez_2008
40 Zhou_2019 Inhibitory Effects of Antiviral Drug Candidates on Canine Parvovirus in F81 cells Zhou, Hongzhuan; Su, Xia; Lin, Lulu; Zhang, Jin; Qi, Qi; Guo, Fangfang; Xu, Fuzhou; Yang, Bing 2019 2019-08-13 COMM-USE N PMC6724046 31412574.0 10.3390/v11080742 24lz9tf1 0.429416 Wu_H_2016, Hsieh_2010
41 McDonagh_2015 Combination siRNA therapy against feline coronavirus can delay the emergence of antiviral resistance in vitro McDonagh, Phillip; Sheehy, Paul A.; Norris, Jacqueline M. 2015 2015-03-23 PMC N PMC7117502 25596968.0 10.1016/j.vetmic.2014.12.009 5raadr4e 0.427074 Hsieh_2010, Wu_H_2016
42 Westover_2018 Galidesivir limits Rift Valley fever virus infection and disease in Syrian golden hamsters Westover, Jonna B.; Mathis, Amanda; Taylor, Ray; Wandersee, Luci; Bailey, Kevin W.; Sefing, Eric J.; Hickerson, Brady T.; Jung, Kie-Hoon; Sheridan, William P.; Gowen, Brian B. 2018 2018-08-31 PMC N 29864447.0 10.1016/j.antiviral.2018.05.013 b9oenhez 0.421900
43 Kim_D_2019 Natural Bis-Benzylisoquinoline Alkaloids-Tetrandrine, Fangchinoline, and Cepharanthine, Inhibit Human Coronavirus OC43 Infection of MRC-5 Human Lung Cells Kim, Dong Eon; Min, Jung Sun; Jang, Min Seong; Lee, Jun Young; Shin, Young Sup; Park, Chul Min; Song, Jong Hwan; Kim, Hyoung Rae; Kim, Seungtaek; Jin, Young-Hee; Kwon, Sunoh 2019 2019-11-04 COMM-USE N PMC6921063 31690059.0 10.3390/biom9110696 5ts3kk10 0.416331 Wu_H_2016
44 Gao_M_2010 Chemical genetics strategy identifies an HCV NS5A inhibitor with a potent clinical effect Gao, Min; Nettles, Richard E.; Belema, Makonen; Snyder, Lawrence B.; Nguyen, Van N.; Fridell, Robert A.; Serrano-Wu, Michael H.; Langley, David R.; Sun, Jin-Hua; O’Boyle II, Donald R.; Lemm, Julie A.; Wang, Chunfu; Knipe, Jay O.; Chien, Caly; Colonno, Richard J.; Grasela, Dennis M.; Meanwell, Nicholas A.; Hamann, Lawrence G. 2010 2010-04-21 None N PMC7094952 20410884.0 10.1038/nature08960 mqicryxr 0.415074
45 Perwitasari_2016 Antiviral Efficacy of Verdinexor In Vivo in Two Animal Models of Influenza A Virus Infection Perwitasari, Olivia; Johnson, Scott; Yan, Xiuzhen; Register, Emery; Crabtree, Jackelyn; Gabbard, Jon; Howerth, Elizabeth; Shacham, Sharon; Carlson, Robert; Tamir, Sharon; Tripp, Ralph A. 2016 2016-11-28 COMM-USE N PMC5125695 27893810.0 10.1371/journal.pone.0167221 i3681ul1 0.413374
46 Goyal_2020 Potency and timing of antiviral therapy as determinants of duration of SARS CoV-2 shedding and intensity of inflammatory response Ashish Goyal; E. Fabian Cardozo-Ojeda; Joshua T Schiffer 2020 2020-04-14 BioRxiv Y 10.1101/2020.04.10.20061325 d7stppv5 0.404521 Shaw_2011 McDonagh_2015
47 Rossignol_2016 Nitazoxanide, a new drug candidate for the treatment of Middle East respiratory syndrome coronavirus Rossignol, Jean-François 2016 2016-06-30 PMC N PMC7102735 27095301.0 10.1016/j.jiph.2016.04.001 1a0fj900 0.403115 Sperber_1987
48 Beaucourt_2014 Ribavirin: a drug active against many viruses with multiple effects on virus replication and propagation. Molecular basis of ribavirin resistance Beaucourt, Stéphanie; Vignuzzi, Marco 2014 2014-10-31 PMC N PMC7102760 24846716.0 10.1016/j.coviro.2014.04.011 ubwpyt3f 0.398620 Lee_C_2019
49 Ge_Y_2020 A data-driven drug repositioning framework discovered a potential therapeutic agent targeting COVID-19 Yiyue Ge; Tingzhong Tian; Suling Huang; Fangping Wan; Jingxin Li; Shuya Li; Hui Yang; Lixiang Hong; Nian Wu; Enming Yuan; Lili Cheng; Yipin Lei; Hantao Shu; Xiaolong Feng; Ziyuan Jiang; Ying Chi; Xiling Guo; Lunbiao Cui; Liang Xiao; Zeng Li; Chunhao Yang; Zehong Miao; Haidong Tang; Ligong Chen; Hainian Zeng; Dan Zhao; Fengcai Zhu; Xiaokun Shen; Jianyang Zeng 2020 2020-03-12 BioRxiv Y 10.1101/2020.03.11.986836 qebbkr6d 0.394359 Tang_2020, Xing_2020
50 Guo_J_2020 Screening of Natural Extracts for Inhibitors against Japanese Encephalitis Virus Infection Guo, Jiao; Jia, Xiaoying; Liu, Yang; Wang, Shaobo; Cao, Junyuan; Zhang, Bo; Xiao, Gengfu; Wang, Wei 2020 2020-02-21 COMM-USE N PMC7038234 31871089.0 10.1128/aac.02373-19 161ck1i9 0.394187
51 Sheahan_2020 An orally bioavailable broad-spectrum antiviral inhibits SARS-CoV-2 and multiple endemic, epidemic and bat coronavirus Timothy P. Sheahan; Amy C. Sims; Shuntai Zhou; Rachel L. Graham; Collin S. Hill; Sarah R. Leist; Alexandra Schäfer; Kenneth H. Dinnon; Stephanie A. Montgomery; Maria L. Agostini; Andrea J. Pruijssers; James D. Chapell; Ariane J. Brown; Gregory R. Bluemling; Michael G. Natchus; Manohar Saindane; Alexander A. Kolykhalov; George Painter; Jennifer Harcourt; Azaibi Tamin; Natalie J. Thornburg; Ronald Swanstrom; Mark R. Denison; Ralph S. Baric 2020 2020-03-20 BioRxiv Y 10.1101/2020.03.19.997890 t5iz3vdz 0.393863
52 Arshad_2020 Prioritisation of potential anti-SARS-CoV-2 drug repurposing opportunities based on ability to achieve adequate target site concentrations derived from their established human pharmacokinetics Usman Arshad; Henry Pertinez; Helen Box; Lee Tatham; Rajith KR Rajoli; Paul Curley; Megan Neary; Joanne Sharp; Neill J Liptrott; Anthony Valentijn; Christopher David; Steve P Rannard; Paul O'Neill; Ghaith Aljayyoussi; Shaun Pennington; Stephen A Ward; David J Back; Saye H Khoo; Patrick G Bray; Giancarlo Biagini; Andrew Owen 2020 2020-04-22 BioRxiv Y 10.1101/2020.04.16.20068379 untuy1e6 0.392740 Ekins_2015
53 Lusvarghi_2016 Griffithsin: An Antiviral Lectin with Outstanding Therapeutic Potential Lusvarghi, Sabrina; Bewley, Carole A. 2016 2016-10-24 COMM-USE N PMC5086628 27783038.0 10.3390/v8100296 ydclax3n 0.384434 Lee_C_2019
54 Jung_2019 Neutralization of Acidic Intracellular Vesicles by Niclosamide Inhibits Multiple Steps of the Dengue Virus Life Cycle In Vitro Jung, Eunhye; Nam, Sangwoo; Oh, Hyeryeon; Jun, Sangmi; Ro, Hyun-Joo; Kim, Baek; Kim, Meehyein; Go, Yun Young 2019 2019-06-18 COMM-USE N PMC6582152 31213630.0 10.1038/s41598-019-45095-1 wmfwl2bh 0.382579 Hsieh_2010, Al‐Bari_2017
55 Hillaire_2011 Assessment of the Antiviral Properties of Recombinant Porcine SP-D against Various Influenza A Viruses In Vitro Hillaire, Marine L. B.; van Eijk, Martin; van Trierum, Stella E.; van Riel, Debby; Saelens, Xavier; Romijn, Roland A.; Hemrika, Wieger; Fouchier, Ron A. M.; Kuiken, Thijs; Osterhaus, Albert D. M. E.; Haagsman, Henk P.; Rimmelzwaan, Guus F. 2011 2011-09-14 COMM-USE N PMC3173486 21935489.0 10.1371/journal.pone.0025005 jz5ms7dy 0.379191 Lee_C_2019
56 Opsenica_2011 A chemotype that inhibits three unrelated pathogenic targets: the botulinum neurotoxin serotype A light chain, P. falciparum malaria, and the Ebola filovirus Opsenica, Igor; Burnett, James C.; Gussio, Rick; Opsenica, Dejan; Todorović, Nina; Lanteri, Charlotte A.; Sciotti, Richard J.; Gettayacamin, Montip; Basilico, Nicoletta; Taramelli, Donatella; Nuss, Jonathan E.; Wanner, Laura; Panchal, Rekha G.; Šolaja, Bogdan A.; Bavari, Sina 2011 2011-03-10 PMC N PMC3056319 21265542.0 10.1021/jm100938u eamctnik 0.372902 O’Brien_2007, Shaw_2011 Lee_C_2019
57 Wong_2014 In Vitro and In Vivo Activity of a Novel Antifungal Small Molecule against Candida Infections Wong, Sarah Sze Wah; Kao, Richard Yi Tsun; Yuen, Kwok Yong; Wang, Yu; Yang, Dan; Samaranayake, Lakshman Perera; Seneviratne, Chaminda Jayampath 2014 2014-01-22 COMM-USE N PMC3899067 24465737.0 10.1371/journal.pone.0085836 jfnj6l41 0.368921 Lee_C_2019
58 Xin_J_2019 Potential use of Pichia pastoris strain SMD1168H expressing DNA topoisomerase I in the screening of potential anti-breast cancer agents Xin, Jian; Mahtar, Wan Nor Azlin Wan; Siah, Poh Chiew; Miswan, Noorizan; Khoo, Boon Yin 2019 2019-04-30 NONCOMM N PMC6522884 31059050.0 10.3892/mmr.2019.10201 h9bzx8un 0.364896
59 Hu_C_2018 Antiviral efficacy of nanoparticulate vacuolar ATPase inhibitors against influenza virus infection Hu, Che-Ming Jack; Chen, You-Ting; Fang, Zih-Syun; Chang, Wei-Shan; Chen, Hui-Wen 2018 2018-12-14 NONCOMM N PMC6298390 30587980.0 10.2147/ijn.s185806 bi2a0btp 0.363183 Al‐Bari_2017, Chen_2013, Lee_C_2019
60 Weston_2020 FDA approved drugs with broad anti-coronaviral activity inhibit SARS-CoV-2 in vitro Stuart Weston; Rob Haupt; James Logue; Krystal Matthews; Matthew B. Frieman 2020 2020-03-27 BioRxiv Y 10.1101/2020.03.25.008482 jbc74lcu 0.359712 Dove_2004, Ekins_2015, Beigel_2010 Jeon_2020
61 Al‐Bari_2017 Targeting endosomal acidification by chloroquine analogs as a promising strategy for the treatment of emerging viral diseases Al‐Bari, Md. Abdul Alim 2017 2017-01-23 COMM-USE N PMC5461643 28596841.0 10.1002/prp2.293 201jppkd 0.359023 Jung_2019, Zhu_X_2015
62 Prabakaran_2009 Combination Therapy Using Chimeric Monoclonal Antibodies Protects Mice from Lethal H5N1 Infection and Prevents Formation of Escape Mutants Prabakaran, Mookkan; Prabhu, Nayana; He, Fang; Hongliang, Qian; Ho, Hui-Ting; Qiang, Jia; TaoMeng,; Goutama, Michael; Kwang, Jimmy 2009 2009-05-22 COMM-USE N PMC2682562 19478856.0 10.1371/journal.pone.0005672 cdm39qt9 0.355926
63 DeWald_2019 In Vivo Activity of Amodiaquine against Ebola Virus Infection DeWald, Lisa Evans; Johnson, Joshua C.; Gerhardt, Dawn M.; Torzewski, Lisa M.; Postnikova, Elena; Honko, Anna N.; Janosko, Krisztina; Huzella, Louis; Dowling, William E.; Eakin, Ann E.; Osborn, Blaire L.; Gahagen, Janet; Tang, Liang; Green, Carol E.; Mirsalis, Jon C.; Holbrook, Michael R.; Jahrling, Peter B.; Dyall, Julie; Hensley, Lisa E. 2019 2019-12-27 COMM-USE N PMC6934550 31882748.0 10.1038/s41598-019-56481-0 nuep8nim 0.348706 Falzarano_2015, Dunning_2014, Wang_2016 Hsieh_2010, Wu_H_2016
64 Rolain_2007 Recycling of chloroquine and its hydroxyl analogue to face bacterial, fungal and viral infections in the 21st century Rolain, Jean-Marc; Colson, Philippe; Raoult, Didier 2007 2007-10-31 PMC N PMC7126847 17629679.0 10.1016/j.ijantimicag.2007.05.015 xc4bxin4 0.341566 Wu_H_2016
65 Ivens_2005 Development of a homogeneous screening assay for automated detection of antiviral agents active against severe acute respiratory syndrome-associated coronavirus Ivens, Tania; Eynde, Christel Van den; Acker, Koen Van; Nijs, Erik; Dams, Géry; Bettens, Eva; Ohagen, Asa; Pauwels, Rudi; Hertogs, Kurt 2005 2005-10-31 PMC N PMC7112772 15961169.0 10.1016/j.jviromet.2005.05.010 q60ege66 0.340173 Zhou_2011
66 Jeon_2020 Identification of antiviral drug candidates against SARS-CoV-2 from FDA-approved drugs Sangeun Jeon; Meehyun Ko; Jihye Lee; Inhee Choi; Soo Young Byun; Soonju Park; David Shum; Seungtaek Kim 2020 2020-03-20 BioRxiv Y 10.1101/2020.03.20.999730 5f95gve3 0.336708 Beigel_2010, Dove_2004, Ekins_2015, García-Serradilla_2019 Zhou_2011, Tan_E_2004
67 Zhao_2016 A novel peptide with potent and broad-spectrum antiviral activities against multiple respiratory viruses Zhao, Hanjun; Zhou, Jie; Zhang, Ke; Chu, Hin; Liu, Dabin; Poon, Vincent Kwok-Man; Chan, Chris Chung-Sing; Leung, Ho-Chuen; Fai, Ng; Lin, Yong-Ping; Zhang, Anna Jin-Xia; Jin, Dong-Yan; Yuen, Kwok-Yung; Zheng, Bo-Jian 2016 2016-02-25 COMM-USE N PMC4766503 26911565.0 10.1038/srep22008 4tx1pdxw 0.335885 Lee_C_2019, Zhu_X_2015, Xiong_2020
68 Warren_2016 Therapeutic Efficacy of the Small Molecule GS-5734 against Ebola Virus in Rhesus Monkeys Warren, Travis K.; Jordan, Robert; Lo, Michael K.; Ray, Adrian S.; Mackman, Richard L.; Soloveva, Veronica; Siegel, Dustin; Perron, Michel; Bannister, Roy; Hui, Hon C.; Larson, Nate; Strickley, Robert; Wells, Jay; Stuthman, Kelly S.; Van Tongeren, Sean A.; Garza, Nicole L.; Donnelly, Ginger; Shurtleff, Amy C.; Retterer, Cary J.; Gharaibeh, Dima; Zamani, Rouzbeh; Kenny, Tara; Eaton, Brett P.; Grimes, Elizabeth; Welch, Lisa S.; Gomba, Laura; Wilhelmsen, Catherine L.; Nichols, Donald K.; Nuss, Jonathan E.; Nagle, Elyse R.; Kugelman, Jeffrey R.; Palacios, Gustavo; Doerffler, Edward; Neville, Sean; Carra, Ernest; Clarke, Michael O.; Zhang, Lijun; Lew, Willard; Ross, Bruce; Wang, Queenie; Chun, Kwon; Wolfe, Lydia; Babusis, Darius; Park, Yeojin; Stray, Kirsten M.; Trancheva, Iva; Feng, Joy Y.; Baraskaus, Ona; Xu, Yili; Wong, Pamela; Braun, Molly R.; Flint, Mike; McMullan, Laura K.; Chen, Shan-Shan; Fearns, Rachel; Swaminathan, Swami; Mayers, Douglas L.; Spiropoulou, Christina F.; Lee, William A.; Nichol, Stuart T.; Cihlar, Tomas; Bavari, Sina 2016 2016-03-02 None N PMC5551389 26934220.0 10.1038/nature17180 df3xig8r 0.334626
69 Kaur_2013 Chikungunya virus: an update on antiviral development and challenges Kaur, Parveen; Chu, Justin Jang Hann 2013 2013-10-31 PMC N PMC7108317 23684571.0 10.1016/j.drudis.2013.05.002 tcy7jrth 0.328524 Wu_H_2016, Lee_C_2019
70 Ekins_2020 Tilorone: a Broad-Spectrum Antiviral Invented in the USA and Commercialized in Russia and beyond Ekins, Sean; Lane, Thomas R.; Madrid, Peter B. 2020 2020-03-25 PMC Y PMC7100484 32215760.0 10.1007/s11095-020-02799-8 t03azbzy 0.328336 Beigel_2010, Jerome_2005 Lee_C_2019, Wu_H_2016, Blaising_2014
71 Li_S_2017 Interferon-omega: Current status in clinical applications Li, Shi-fang; Zhao, Fu-rong; Shao, Jun-jun; Xie, Yin-li; Chang, Hui-yun; Zhang, Yong-guang 2017 2017-11-30 PMC N PMC7106160 28957693.0 10.1016/j.intimp.2017.08.028 b1e0bbrp 0.325348 Jerome_2005 Doménech_2011
72 Lv_B_2018 Drug Repurposing for Japanese Encephalitis Virus Infection by Systems Biology Methods Lv, Bo-Min; Tong, Xin-Yu; Quan, Yuan; Liu, Meng-Yuan; Zhang, Qing-Ye; Song, Yun-Feng; Zhang, Hong-Yu 2018 2018-12-18 COMM-USE N PMC6320907 30567313.0 10.3390/molecules23123346 rrazeehl 0.321138
73 Bhowmick_2016 Para-Phenylenediamine Induces Apoptotic Death of Melanoma Cells and Reduces Melanoma Tumour Growth in Mice Bhowmick, Debajit; Bhar, Kaushik; Mallick, Sanjaya K.; Das, Subhadip; Chatterjee, Nabanita; Sarkar, Tuhin Subhra; Chakrabarti, Rajarshi; Das Saha, Krishna; Siddhanta, Anirban 2016 2016-05-17 COMM-USE N PMC4886052 27293892.0 10.1155/2016/3137010 q4qkxp5u 0.316467 Chen_2019
74 Cheng_2011 In vitro transcriptomic prediction of hepatotoxicity for early drug discovery Cheng, Feng; Theodorescu, Dan; Schulman, Ira G.; Lee, Jae K. 2011 2011-12-01 PMC N PMC3386613 21884709.0 10.1016/j.jtbi.2011.08.009 kjkixcx7 0.312719 Park_2012 Chiba_2012, van_der_Kooy_2013
75 Lee_C_2019 Griffithsin, a Highly Potent Broad-Spectrum Antiviral Lectin from Red Algae: From Discovery to Clinical Application Lee, Choongho 2019 2019-10-06 COMM-USE N PMC6835697 31590428.0 10.3390/md17100567 gxbrgy6g 0.305016 Lusvarghi_2016
76 Mathieu_2018 Fusion Inhibitory Lipopeptides Engineered for Prophylaxis of Nipah Virus in Primates Mathieu, Cyrille; Porotto, Matteo; Figueira, Tiago N; Horvat, Branka; Moscona, Anne 2018 2018-03-16 PMC N PMC6009590 29566184.0 10.1093/infdis/jiy152 26pbzbxz 0.300572 Hsieh_2010, Wu_H_2016