Topic 09 -- Abstracts with Biological Entities (English) - 75 Topics / Sub-Topic Model 03 - 15 Topics

cite ad title authors publish year publish time dataset abstract mentions covid pmcid pubmed id doi cord uid topic weight Similarity scispacy Similarity specter
1 Fara_2007 Integration of virtual and physical screening Fara, Dan C.; Oprea, Tudor I.; Prossnitz, Eric R.; Bologa, Cristian G.; Edwards, Bruce S.; Sklar, Larry A. 2007 2007-02-28 PMC N PMC7105924 10.1016/j.ddtec.2006.11.003 ulci5n8t 0.835660 UNKNOWN_2020 Muegge_2007
2 Muegge_2007 Advances in virtual screening Muegge, Ingo; Oloff, Scott 2007 2007-02-28 PMC N PMC7105922 10.1016/j.ddtec.2006.12.002 6592zctb 0.793273 UNKNOWN_2020 Fara_2007
3 Oxenoid_2013 The present and future of solution NMR in investigating the structure and dynamics of channels and transporters Oxenoid, Kirill; Chou, James J 2013 2013-08-31 None N PMC3740178 23628285.0 10.1016/j.sbi.2013.03.010 f4c7r8dx 0.751727 UNKNOWN_2004
4 Zoete_2009 Docking, virtual high throughput screening and in silico fragment-based drug design Zoete, Vincent; Grosdidier, Aurélien; Michielin, Olivier 2009 2009-01-21 PMC N PMC3823351 19183238.0 10.1111/j.1582-4934.2008.00665.x xmbzmeo4 0.729437 Weber_2009, May_E_2016
5 Subramaniam_2016 Resolution advances in cryo-EM enable application to drug discovery Subramaniam, Sriram; Earl, Lesley A.; Falconieri, Veronica; Milne, Jacqueline L. S.; Egelman, Edward H. 2016 2016-12-01 PMC N PMC5154827 27552081.0 10.1016/j.sbi.2016.07.009 n6ett8uo 0.712383
6 Chilingaryan_2012 Fragment-Based Screening by Protein Crystallography: Successes and Pitfalls Chilingaryan, Zorik; Yin, Zhou; Oakley, Aaron J. 2012 2012-10-08 COMM-USE N PMC3497300 23202926.0 10.3390/ijms131012857 6qfy7597 0.705437 Weinrich_2009, Kosuri_2014, Uprichard_2005 Grey_2010
7 Bassetto_2016 Structural biology in antiviral drug discovery Bassetto, Marcella; Massarotti, Alberto; Coluccia, Antonio; Brancale, Andrea 2016 2016-10-31 PMC N 27611878.0 10.1016/j.coph.2016.08.014 3eoio8uk 0.697971
8 Kramer_2012 Detection of ubiquitin–proteasome enzymatic activities in cells: Application of activity-based probes to inhibitor development Kramer, Holger B.; Nicholson, Benjamin; Kessler, Benedikt M.; Altun, Mikael 2012 2012-11-30 PMC N PMC7125640 22613766.0 10.1016/j.bbamcr.2012.05.014 tq82srhn 0.671567
9 Fukai_2016 Application of MultiBac System to Large Complexes Fukai, Shuya 2016 2016-03-03 PMC N PMC7121899 10.1007/978-4-431-56030-2_3 sy3ri0k9 0.668946 UNKNOWN_2004 Bieniossek_2012
10 Pandey_2016 Current strategies for protein production and purification enabling membrane protein structural biology Pandey, Aditya; Shin, Kyungsoo; Patterson, Robin E.; Liu, Xiang-Qin; Rainey, Jan K. 2016 2016-12-01 PMC N PMC5752365 27010607.0 10.1139/bcb-2015-0143 9k2z7xri 0.665197
11 Crépin_2015 Polyproteins in structural biology Crépin, Thibaut; Swale, Christopher; Monod, Alexandre; Garzoni, Frederic; Chaillet, Maxime; Berger, Imre 2015 2015-06-30 PMC N PMC7125721 25996897.0 10.1016/j.sbi.2015.04.007 r18br8a4 0.652992
12 Takeda_2012 1.12 Labeling Techniques Takeda, M.; Kainosho, M. 2012 2012-12-31 PMC N PMC7151895 10.1016/b978-0-12-374920-8.00116-8 cvib20ca 0.649702 Fotopoulou_2018, May_E_2016 Kainosho_2017
13 Horiuchi_2005 Biochemical Microarrays for Studying Chemical Biology Interaction: DiscoveryDot(TM) Technology Horiuchi, Kurumi Y.; Wang, Yuan; Ma, Haiching 2005 2005-12-21 PMC N PMC7162007 16492155.0 10.1111/j.1747-0285.2005.00326.x 65e8ol64 0.622642 Hu_S_2010, Sharon_2010
14 Schmidt_2009 Dynamic template-assisted strategies in fragment-based drug discovery Schmidt, Marco F.; Rademann, Jörg 2009 2009-09-30 PMC N PMC7114311 19679363.0 10.1016/j.tibtech.2009.06.001 lo8nxtwl 0.612091 Webb_2014 Makara_2005
15 Grey_2010 Challenges and Opportunities for New Protein Crystallization Strategies in Structure-Based Drug Design Grey, Jessica; Thompson, David 2010 2010-09-08 PMC N PMC2992350 21116481.0 10.1517/17460441.2010.515583 vg2voalu 0.602921 Zoete_2009, Weber_2009, Webb_2014
16 Farhadi_2018 Computer-aided design of amino acid-based therapeutics: a review Farhadi, Tayebeh; Hashemian, Seyed MohammadReza 2018 2018-05-14 NONCOMM N PMC5958949 29795978.0 10.2147/dddt.s159767 q69f57el 0.600962 UNKNOWN_2004, Sztuba-Solinska_2019, Johnson_2018, Weber_2009
17 To_J_2016 Chapter Eight Targeting the Channel Activity of Viroporins To, Janet; Surya, Wahyu; Torres, Jaume 2016 2016-12-31 PMC N PMC7102763 27038378.0 10.1016/bs.apcsb.2015.12.003 1kt51viz 0.594547
18 Ekkebus_2014 Catching a DUB in the act: novel ubiquitin-based active site directed probes Ekkebus, Reggy; Flierman, Dennis; Geurink, Paul P; Ovaa, Huib 2014 2014-12-31 PMC N 25461387.0 10.1016/j.cbpa.2014.10.005 7z7mu6gn 0.589345
19 Tooze_1991 Secretory granule formation: The morphologist’s view Tooze, John 1991 1991-01-01 PMC N PMC7090665 1726882.0 10.1007/bf02989885 uzzoji4z 0.589345
20 Kainosho_2017 Isotope-Aided Methods for Biological NMR Spectroscopy: Past, Present, and Future Kainosho, Masatsune; Miyanoiri, Yohei; Takeda, Mitsuhiro 2017 2017-07-24 PMC N PMC7122432 10.1007/978-981-10-5966-7_2 9hkg34u6 0.572253 UNKNOWN_2004
21 Prada-Gracia_2016 Application of computational methods for anticancer drug discovery, design, and optimization Prada-Gracia, Diego; Huerta-Yépez, Sara; Moreno-Vargas, Liliana M. 2016 2016-12-31 PMC N PMC7110968 29421286.0 10.1016/j.bmhimx.2016.10.006 rp1vvwav 0.567721 Weber_2009, Johnson_2018, Prada-Gracia_2016 Prada-Gracia_2016
22 Sanchez-Weatherby_2016 Crystal Dehydration in Membrane Protein Crystallography Sanchez-Weatherby, Juan; Moraes, Isabel 2016 2016-04-28 COMM-USE N PMC6126552 27553236.0 10.1007/978-3-319-35072-1_6 ssp499fe 0.561067 UNKNOWN_2004
23 Curthoys_2015 Chapter Three Dances with Membranes: Breakthroughs from Super-resolution Imaging Curthoys, Nikki M.; Parent, Matthew; Mlodzianoski, Michael; Nelson, Andrew J.; Lilieholm, Jennifer; Butler, Michael B.; Valles, Matthew; Hess, Samuel T. 2015 2015-12-31 PMC N 26015281.0 10.1016/bs.ctm.2015.03.008 vid6m563 0.557890 UNKNOWN_2004, Johnson_2018
24 Zhai_2019 SmartBac, a new baculovirus system for large protein complex production Zhai, Yujia; Zhang, Danyang; Yu, Leiye; Sun, Fang; Sun, Fei 2019 2019-03-31 PMC N 10.1016/j.yjsbx.2019.100003 o30zylrq 0.547676
25 Neefjes_2004 Fluorescent probes for proteolysis: Tools for drug discovery Neefjes, Jacques; Dantuma, Nico P. 2004 2004-01-01 PMC N PMC7097193 14708021.0 10.1038/nrd1282 k6oycubu 0.544478
26 Zhou_2009 Overcoming the Solubility Limit with Solubility-Enhancement Tags: Successful Applications in Biomolecular NMR Studies Zhou, Pei; Wagner, Gerhard 2009 2009-09-03 PMC N PMC2879018 19731047.0 10.1007/s10858-009-9371-6 4lfj9cwo 0.536950 Johnson_2018, UNKNOWN_2004, Weinrich_2009 Munusamy_2020
27 Berger_2015 Baculovirus expression: old dog, new tricks Berger, Imre; Poterszman, Arnaud 2015 2015-10-21 None N PMC4825837 26488462.0 10.1080/21655979.2015.1104433 9x3av6za 0.529482 Conzelmann_1996, UNKNOWN_2004
28 Benjin_2019 Developments, applications, and prospects of cryo‐electron microscopy Benjin, Xu; Ling, Liu 2019 2019-12-26 PMC N PMC7096719 31854478.0 10.1002/pro.3805 kvuti410 0.529482 UNKNOWN_2004, Johnson_2018
29 Liu_T_2016 Applying high-performance computing in drug discovery and molecular simulation Liu, Tingting; Lu, Dong; Zhang, Hao; Zheng, Mingyue; Yang, Huaiyu; Xu, Yechun; Luo, Cheng; Zhu, Weiliang; Yu, Kunqian; Jiang, Hualiang 2016 2016-01-11 COMM-USE N PMC7107815 10.1093/nsr/nww003 wnbyy1gk 0.525265 UNKNOWN_2020, Duan_2015
30 Vijayachandran_2011 Robots, pipelines, polyproteins: Enabling multiprotein expression in prokaryotic and eukaryotic cells Vijayachandran, Lakshmi Sumitra; Viola, Cristina; Garzoni, Frederic; Trowitzsch, Simon; Bieniossek, Christoph; Chaillet, Maxime; Schaffitzel, Christiane; Busso, Didier; Romier, Christophe; Poterszman, Arnaud; Richmond, Timothy J.; Berger, Imre 2011 2011-08-31 PMC N PMC7128143 21419851.0 10.1016/j.jsb.2011.03.007 5aomx7a2 0.519288 Conzelmann_1996
31 Prada-Gracia_2016 Application of computational methods for anticancer drug discovery, design, and optimization Prada-Gracia, Diego; Huerta-Yépez, Sara; Moreno-Vargas, Liliana M. 2016 2016-12-31 PMC N PMC7154613 10.1016/j.bmhime.2017.11.040 jlol01b8 0.517679 Weber_2009, Johnson_2018, Prada-Gracia_2016 Prada-Gracia_2016
32 Pang_2006 In Silico Drug Discovery: Solving the “Target‐rich and Lead‐poor” Imbalance Using the Genome‐to‐drug‐lead Paradigm Pang, Y P 2006 2006-12-14 PMC N PMC7162381 17185996.0 10.1038/sj.clpt.6100030 e09fyykq 0.513397
33 Engel_1994 The aquaporin family of membrane water channels Engel, Andreas; Walz, Thomas; Agre, Peter 1994 1994-12-31 PMC N 10.1016/s0959-440x(94)90217-8 bhjpvwbg 0.512673
34 Webb_2014 Comparative Modeling of Drug Target Proteins☆ Webb, B.; Eswar, N.; Fan, H.; Khuri, N.; Pieper, U.; Dong, G.Q.; Sali, A. 2014 2014-12-31 PMC N PMC7157477 10.1016/b978-0-12-409547-2.11133-3 d66rz6dc 0.503753 Eswar_2007, Johnson_2018 Eswar_2007
35 Pelosse_2017 MultiBac: from protein complex structures to synthetic viral nanosystems Pelosse, Martin; Crocker, Hannah; Gorda, Barbara; Lemaire, Paul; Rauch, Jens; Berger, Imre 2017 2017-10-30 COMM-USE N PMC5661938 29084535.0 10.1186/s12915-017-0447-6 kvvxmvqo 0.501874 Conzelmann_1996, Jang_2018
36 Rao_Z_2007 History of protein crystallography in China Rao, Zihe 2007 2007-02-27 PMC N PMC2435569 17327211.0 10.1098/rstb.2007.2032 k46ukxcr 0.501620 UNKNOWN_2013, UNKNOWN_2020
37 Sari_2015 The MultiBac Baculovirus/Insect Cell Expression Vector System for Producing Complex Protein Biologics Sari, Duygu; Gupta, Kapil; Raj, Deepak Balaji Thimiri Govinda; Aubert, Alice; Drncová, Petra; Garzoni, Frederic; Fitzgerald, Daniel; Berger, Imre 2015 2015-12-12 PMC N PMC7122245 27165327.0 10.1007/978-3-319-27216-0_13 jkfsqqy4 0.494784 Conzelmann_1996
38 Ma_H_2006 Chemical microarray: a new tool for drug screening and discovery Ma, Haiching; Horiuchi, Kurumi Y. 2006 2006-07-31 None N PMC2577215 16793536.0 10.1016/j.drudis.2006.05.002 0smev8vt 0.475148 Sharon_2010, Weber_2009, Connelly_2016, UNKNOWN_2004
39 Betz_2006 Biomolecular NMR: a chaperone to drug discovery Betz, Marco; Saxena, Krishna; Schwalbe, Harald 2006 2006-06-30 PMC N 16679046.0 10.1016/j.cbpa.2006.04.006 mzndovza 0.474787 UNKNOWN_2004, Weber_2009, Weinrich_2009, Johnson_2018
40 Li_N_2020 Cryo-EM Studies of Virus-Antibody Immune Complexes Li, Na; Li, Zhiqiang; Fu, Yan; Cao, Sheng 2020 2020-01-08 COMM-USE N PMC7035235 31916022.0 10.1007/s12250-019-00190-5 aap4xua5 0.470059 Conzelmann_1996
41 Bieniossek_2012 MultiBac: expanding the research toolbox for multiprotein complexes Bieniossek, Christoph; Imasaki, Tsuyoshi; Takagi, Yuichiro; Berger, Imre 2012 2012-02-29 PMC N PMC7127121 22154230.0 10.1016/j.tibs.2011.10.005 gfx4cq03 0.467525 UNKNOWN_2004 Fukai_2016
42 van_der_Vlag_2017 5.20 Analytical Methods in Protein-Templated Dynamic Combinatorial Chemistry van der Vlag, R.; Hirsch, A.K.H. 2017 2017-12-31 PMC N PMC7150222 10.1016/b978-0-12-409547-2.12559-4 b0rcg3rt 0.464420
43 Mlostoń_2010 Synthesis of β-amino-α-trifluoromethyl alcohols and their applications in organic synthesis Mlostoń, Grzegorz; Obijalska, Emilia; Heimgartner, Heinz 2010 2010-08-31 PMC N PMC7125969 10.1016/j.jfluchem.2010.05.014 b3ukefxq 0.458045
44 Kemp_2016 Chapter Three Recent Advances in the Discovery of Deubiquitinating Enzyme Inhibitors Kemp, Mark 2016 2016-12-31 PMC N PMC7112275 26852935.0 10.1016/bs.pmch.2015.10.002 mrltpnyw 0.453631 Sztuba-Solinska_2019, Johnson_2018
45 Hogue_2015 Fluorescent Protein Approaches in Alpha Herpesvirus Research Hogue, Ian B.; Bosse, Jens B.; Engel, Esteban A.; Scherer, Julian; Hu, Jiun-Ruey; del Rio, Tony; Enquist, Lynn W. 2015 2015-11-19 COMM-USE N PMC4664988 26610544.0 10.3390/v7112915 uv6zb2qj 0.444476 Conzelmann_1996, Johnson_2018
46 Makara_2005 Improving success rates for lead generation using affinity binding technologies Makara, Gergely M; Athanasopoulos, John 2005 2005-12-31 PMC N PMC7126921 16257522.0 10.1016/j.copbio.2005.10.007 g60iybhk 0.435220 Connelly_2016, Sztuba-Solinska_2019, Conzelmann_1996
47 Barford_2013 Baculovirus expression: tackling the complexity challenge Barford, David; Takagi, Yuichiro; Schultz, Patrick; Berger, Imre 2013 2013-06-30 PMC N PMC7125881 23628287.0 10.1016/j.sbi.2013.03.009 n02j3cio 0.428166 UNKNOWN_2004 Bieniossek_2012
48 Chou_2011 Some remarks on protein attribute prediction and pseudo amino acid composition Chou, Kuo-Chen 2011 2011-03-21 PMC N PMC7125570 21168420.0 10.1016/j.jtbi.2010.12.024 2scgsmsc 0.423379
49 Zhang_2019 Advances that facilitate the study of large RNA structure and dynamics by nuclear magnetic resonance spectroscopy Zhang, Huaqun; Keane, Sarah C. 2019 2019-04-25 PMC N PMC7169810 31025514.0 10.1002/wrna.1541 8x37nx4s 0.415723
50 Morgan_2018 Insights into the development of chemical probes for RNA Morgan, Brittany S; Forte, Jordan E; Hargrove, Amanda E 2018 2018-09-19 NONCOMM N PMC6144806 30102391.0 10.1093/nar/gky718 wupre5uj 0.412343 Sztuba-Solinska_2019, Ching_2015, Johnson_2018 Connelly_2016, Behlke_2006
51 Eswar_2007 4.10 Comparative Modeling of Drug Target Proteins Eswar, N.; Sali, A. 2007 2007-12-31 PMC N PMC7151936 10.1016/b0-08-045044-x/00251-0 oqxh7egj 0.397254 Webb_2014, Johnson_2018 Webb_2014
52 Bárcena_2009 Electron tomography in life science Bárcena, Montserrat; Koster, Abraham J. 2009 2009-10-31 PMC N PMC7110493 19664718.0 10.1016/j.semcdb.2009.07.008 x5ghdawo 0.396411 UNKNOWN_2004, Janjić_2012, May_E_2016, Johnson_2018, Conzelmann_1996
53 Giegé_2010 Biocrystallography: past, present, future Giegé, Richard; Sauter, Claude 2010 2010-06-01 PMC N PMC2929629 21119764.0 10.2976/1.3369281 xl9qhcm8 0.391898 UNKNOWN_2004, Johnson_2018, Janjić_2012
54 Sztuba-Solinska_2019 Unveiling the druggable RNA targets and small molecule therapeutics Sztuba-Solinska, Joanna; Chavez-Calvillo, Gabriela; Cline, Sabrina Elizabeth 2019 2019-05-15 PMC N PMC7126819 30981606.0 10.1016/j.bmc.2019.03.057 4ijrdkxe 0.382556 UNKNOWN_2004, Johnson_2018, Connelly_2016 Connelly_2016
55 Gai_S_2007 Yeast surface display for protein engineering and characterization Gai, S Annie; Wittrup, K Dane 2007 2007-08-31 None N PMC4038029 17870469.0 10.1016/j.sbi.2007.08.012 vcx1acr9 0.379388
56 Roy_M_2018 Lycorine: A prospective natural lead for anticancer drug discovery Roy, Mridul; Liang, Long; Xiao, Xiaojuan; Feng, Peifu; Ye, Mao; Liu, Jing 2018 2018-11-30 PMC N PMC7127747 30114645.0 10.1016/j.biopha.2018.07.147 1p2r5xjc 0.367696 Uprichard_2005, Weber_2009
57 Jacques_2010 Small-angle scattering for structural biology—Expanding the frontier while avoiding the pitfalls Jacques, David A; Trewhella, Jill 2010 2010-01-29 PMC N PMC2867006 20120026.0 10.1002/pro.351 eg63bjl5 0.353465 Giegé_2010
58 Prasad_2011 Principles of Virus Structural Organization Prasad, B.V. Venkataram; Schmid, Michael F 2011 2011-11-08 None N PMC3767311 22297509.0 10.1007/978-1-4614-0980-9_3 m159iz5j 0.345602 UNKNOWN_2004, Johnson_2018, Conzelmann_1996
59 Hraber_2020 Resources to Discover and Use Short Linear Motifs in Viral Proteins Hraber, Peter; O’Maille, Paul E.; Silberfarb, Andrew; Davis-Anderson, Katie; Generous, Nicholas; McMahon, Benjamin H.; Fair, Jeanne M. 2020 2020-01-31 PMC N PMC7114124 31427097.0 10.1016/j.tibtech.2019.07.004 5vjqrnwh 0.338080
60 Schwartz_2008 Cost effective strategies for completing the Interactome Schwartz, Ariel S.; Yu, Jingkai; Gardenour, Kyle R.; Finley, Russell L.; Ideker, Trey 2008 2008-12-14 None N PMC2613168 19079254.0 10.1038/nmeth.1283 iar66keo 0.334407 Webb_2014
61 Hall_2007 Protein microarray technology Hall, David A.; Ptacek, Jason; Snyder, Michael 2007 2007-01-31 None N PMC1828913 17126887.0 10.1016/j.mad.2006.11.021 1ty623bq 0.327559 Hu_S_2010, Sztuba-Solinska_2019, Sharon_2010 Hu_S_2010, Berrade_2010
62 Anthonsen_1994 The blind watchmaker and rational protein engineering Anthonsen, Henrik W.; Baptista, António; Drabløs, Finn; Martel, Paulo; Petersen, Steffen B. 1994 1994-08-31 PMC N 7765263.0 10.1016/0168-1656(94)90152-x 8lnpujip 0.318841 UNKNOWN_2004
63 Wang_2016 Biological cryo‐electron microscopy in China Wang, Hong‐Wei; Lei, Jianlin; Shi, Yigong 2016 2016-09-02 NONCOMM N PMC5192968 27534377.0 10.1002/pro.3018 crmlsbpo 0.306527 UNKNOWN_2020 Subramaniam_2016
64 Varki_2016 Biological roles of glycans Varki, Ajit 2016 2016-08-24 PMC N PMC5884436 27558841.0 10.1093/glycob/cww086 iqi9d0jc 0.303521 UNKNOWN_2004
65 Hillisch_2004 Utility of homology models in the drug discovery process Hillisch, Alexander; Pineda, Luis Felipe; Hilgenfeld, Rolf 2004 2004-08-31 PMC N PMC7129151 15279849.0 10.1016/s1359-6446(04)03196-4 02bik024 0.301424 Webb_2014 Bassetto_2016
66 Ding_2012 Chapter Six Molecular Mechanics of RNA Translocases Ding, Steve C.; Pyle, Anna Marie 2012 2012-12-31 None N PMC4407658 22713318.0 10.1016/b978-0-12-396546-2.00006-1 igkhn4m4 0.301424 UNKNOWN_2004